| Abstract |
A process for the preparation of pharmacologically active novel acyl labdane derivatives of the formula I shown in the accompanying drawings wherein R stands for vinyl, R stands for hydrogen or a group of the formula R R R Si wherein R R and R are each independently alkyl, R stands for a group of the formula shown in Fig.l of the accompanying drawings wherein A stands for OR r wherein R„ stands for alkyl or A stands for the group shown in the Fig.2 of the accompanying drawings, wherein when X and Y are the same they stand for hydrogen or alkyl,. when X stands for hydrogen or lower alkyl, Y stands for alkyl/ substituted alkyl, cycloalkyl, aralkyl, aryl, amino or hydroxy, X and Y together with the nitrogen atom to which they are attached form a heterocyclic ring containing optionally an additional hetero atom and is optionally substituted by alkyl or aryl, Rfi stands for a group shown in Fig.3 of the accompanying drawings wherein m and n stand for integers 0-10, and R and R which may be the same stand for hydrogen or lower alkyl when R stands for hydrogen, R stands for hydroxy, thiol, alkyl or aryl, R stands for hydrogen, R stands for hydrogen, hydroxy or alkyl, X1 stands for hydrogen when Y stands for hydrogen, alkyl, substituted alkyl, alkanoyl, aryl, cycloalkyl, aralkyl, aryl, heterocycle, amino, substituted amino, hydroxy/ acyl, dialkylaminoalkyl/ carbamoyl/ carboxylalkyl or carbalkoxy alkyl/ when X, and Y-, are the same they stand for alkyl, substituted alkyl, aryl or aralkyl, when X-j^ stands for alkyl, Y stands for substituted alkyl, cycloalkyl/ aralkyl, dialkylamino or alkyl when X and Y together with the nitrogen |