Title of Invention

PROCESS FOR THE MANUFACTURE OF AN ALKALI METAL SALT OF L-ASCORBIC ACID 2-MONOPHOSPHATE

Abstract The invention relates to a process for the manufacture of an alkali metal or alkaline earth metal salt of L-ascorbic acid 2-monophosphate of formula I. The said process comprising reacting with a concentrated aqueous solution of anm alkali metal or alkaline earth metal salt of L-ascorbic acid of formula III, in the presence of an alkaline earth metal hydroxide as a base, a L-ascorbic acid 2-polyphosphate of formula II. The said compound of formula II preferably being produced in situ by adding to the compound of formula III a phosphorylating agent. The pH of the reaction medium is in the range of 8 to 11 and after essentially all the added or in situ produced polyphosphate has been consumed in the reaction the L-ascorbic acid 2-monophospate salt of formula I is recovered in a known manner from the mixture.
Full Text

Documents:

467-mas-1998 abstract.pdf

467-mas-1998 claims granted.pdf

467-mas-1998 correspondence others.pdf

467-mas-1998 description (complete) granted.pdf

467-mas-1998 form-1.pdf

467-mas-1998 form-4.pdf

467-mas-1998 form-6.pdf

467-mas-1998 petitions.pdf

467-mas-1998 power of attorney.pdf


Patent Number 186465
Indian Patent Application Number 467/MAS/1998
PG Journal Number 30/2009
Publication Date 24-Jul-2009
Grant Date 05-Apr-2002
Date of Filing 06-Mar-1998
Name of Patentee M/S. F HOFFMANN-LA ROCHE AG
Applicant Address 124 GRENZACHERSTRASSE, CH-4070 BASLE
Inventors:
# Inventor's Name Inventor's Address
1 ALAIN DLUBALA 5 IMPASSE DE LA COMBE, F-30133 LES ANGLES,
2 PAUL NOSBERGER 1 PASSWANGSTRASSE, CH-4127 BIRSFELDEN,
PCT International Classification Number C07D 307/02
PCT International Application Number N/A
PCT International Filing date
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 NA