Title of Invention | PROCESS FOR THE MANUFACTURE OF AN ALKALI METAL SALT OF L-ASCORBIC ACID 2-MONOPHOSPHATE |
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Abstract | The invention relates to a process for the manufacture of an alkali metal or alkaline earth metal salt of L-ascorbic acid 2-monophosphate of formula I. The said process comprising reacting with a concentrated aqueous solution of anm alkali metal or alkaline earth metal salt of L-ascorbic acid of formula III, in the presence of an alkaline earth metal hydroxide as a base, a L-ascorbic acid 2-polyphosphate of formula II. The said compound of formula II preferably being produced in situ by adding to the compound of formula III a phosphorylating agent. The pH of the reaction medium is in the range of 8 to 11 and after essentially all the added or in situ produced polyphosphate has been consumed in the reaction the L-ascorbic acid 2-monophospate salt of formula I is recovered in a known manner from the mixture. |
Full Text |
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467-mas-1998 claims granted.pdf
467-mas-1998 correspondence others.pdf
467-mas-1998 description (complete) granted.pdf
467-mas-1998 power of attorney.pdf
Patent Number | 186465 | |||||||||
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Indian Patent Application Number | 467/MAS/1998 | |||||||||
PG Journal Number | 30/2009 | |||||||||
Publication Date | 24-Jul-2009 | |||||||||
Grant Date | 05-Apr-2002 | |||||||||
Date of Filing | 06-Mar-1998 | |||||||||
Name of Patentee | M/S. F HOFFMANN-LA ROCHE AG | |||||||||
Applicant Address | 124 GRENZACHERSTRASSE, CH-4070 BASLE | |||||||||
Inventors:
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PCT International Classification Number | C07D 307/02 | |||||||||
PCT International Application Number | N/A | |||||||||
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PCT Conventions:
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