Title of Invention

PROCESS FOR THE PREPARATION OF NEW DERIVATIVES OF HYDANTOINS, THIOHYDANTOINS, PYRIMIDINEDIONES AND THIOXOPYRIMIDINONES

Abstract

The invention concerns compounds for treating pathological conditions or diseases wherein one (or several) somatostatin receptors is (are) involved, corresponding to general formula (I) wherein: R1 represents in particular a carbocyclic or heterocyclic aryl radical optionally substituted or a non-aromatic heterocyclic radical optionally substituted; R2 represents H, alkyl or aryl optionally substituted; R3 represents H or -(CH2)p-Z3, Z3 representing in particular alkyl, cycloalkyl, bis-arylalkyl or di-aryalkyl, -Y1-(CH2)p-phenyl-(X1)n, carbocyclic or heterocyclic aryl optionally substituted, a non-aromatic heterocyclic radical optionally substituted, X1, every time it is present, being independently selected in particular among the radicals H, Cl, F, Br, I, CF3, NO2, OH, NH2, CN, N3, -OCF3, alkyl, alkoxy, -S-alkyl, -(CH2)p-NH2, -(CH2)p-NH-alkyl, -(CH2)p-N-dialkyl; Y1 represents O, S, NH or is not present; R4 represents -(CH2)p-Z4, Z4 representing in particular amino, alkylamino, N,N-dialkylamino; R5 represents in particular H or alkyl; X represents O or S; p each time it is present is independently 0 or an integer ranging between 1 and 6; q each time it is present is independently an integer between 1 and 5; n represents 0 or 1; provided that when n represents 0, m represents 1, 2 or 3, and when n represents 1, m represents 0 or 1.

Full Text	N/A

Documents:

abstract1.jpg

in-pct-2002-00081-mum-cancelled pages(17-10-2005).pdf

in-pct-2002-00081-mum-cancelled pages(3-10-2005).pdf

in-pct-2002-00081-mum-claims(amended)-(24-10-2005).pdf

in-pct-2002-00081-mum-claims(complete)-(22-1-2002).pdf

in-pct-2002-00081-mum-claims(granted)-(17-10-2005).doc

in-pct-2002-00081-mum-claims(granted)-(17-10-2005).pdf

in-pct-2002-00081-mum-claims(granted)-(24-8-2007).pdf

in-pct-2002-00081-mum-correspondence(25-10-2005).pdf

in-pct-2002-00081-mum-correspondence(ipo)-(17-9-2007).pdf

in-pct-2002-00081-mum-correspondence(ipo)-(24-8-2007).pdf

in-pct-2002-00081-mum-description(complete)-(22-1-2002).pdf

in-pct-2002-00081-mum-description(granted)-(24-8-2007).pdf

in-pct-2002-00081-mum-form 19(23-6-2004).pdf

in-pct-2002-00081-mum-form 1a(17-10-2005).pdf

in-pct-2002-00081-mum-form 1a(22-1-2002).pdf

in-pct-2002-00081-mum-form 1a(3-10-2005).pdf

in-pct-2002-00081-mum-form 2(granted)-(17-10-2005).doc

in-pct-2002-00081-mum-form 2(granted)-(17-10-2005).pdf

in-pct-2002-00081-mum-form 2(granted)-(24-8-2007).pdf

in-pct-2002-00081-mum-form 2(title page)-(granted)-(24-8-2007).pdf

in-pct-2002-00081-mum-form 3(22-1-2002).pdf

in-pct-2002-00081-mum-form 3(24-10-2005).pdf

in-pct-2002-00081-mum-form 5(22-1-2002).pdf

in-pct-2002-00081-mum-petition of under rule 137(24-10-2005).pdf

in-pct-2002-00081-mum-power of authority(15-3-2002).pdf

IN-PCT-2002-00081-MUM-POWER OF AUTHORITY(19-03-2002).pdf

in-pct-2002-00081-mum-power of authority(26-10-2005).pdf

in-pct-2002-00081-mum-power of authority(3-10-2005).pdf

in-pct-2002-00081-mum-specification(amended)-(17-10-2005).pdf

in-pct-2002-00081-mum-specification(amended)-(3-10-2005).pdf

in-pct-2002-00081-mum-wo international publication report(22-1-2002).pdf