| Title of Invention | A MULTI-LAYERED RAPID AND CONTROLLED RELEASE SOLID PHARMACEUTICAL FORMULATION |
|---|---|
| Abstract | Sulfoalkyl ether cyclodextrin (SAE-CD) based controlled release pharmaceutical formulations are provided by the present invention. The present solid pharmaceutical formulations consist of a core comprising a physical mixture of one or more SAE-CD derivatives, an optional release rate modifier, a therapeutic agent, a major portion of which is not complexed to the SAE-CD, and an optional release rate modifying coating surrounding the core. The present formulation are advantageously easier to prepare than other SAE-CD, and an optional release formulation in the art yet provide similar or improved effectiveness. The SAE-CD derivative is used to modify the bioavailability and/or rate of bioabsorption of therapeutic agents. Multi-layered, osmotic pump, coated, and uncoated tablet, minitablet, pellet, micropellet, particle, powder, and granule dosage forms are disclosed herein. |
| Full Text | N/A |
|---|
241-mumnp-2005-claims(granted)-(17-04-2006).doc
241-mumnp-2005-claims(granted)-(17-04-2006).pdf
241-mumnp-2005-correspondence(17-04-2006).pdf
241-mumnp-2005-correspondence(ipo)-(20-10-2005).pdf
241-mumnp-2005-drawing(17-04-2006).pdf
241-mumnp-2005-form 1(31-03-2005).pdf
241-mumnp-2005-form 13(13-09-2005).pdf
241-mumnp-2005-form 2(granted)-(17-04-2006).doc
241-mumnp-2005-form 2(granted)-(17-04-2006).pdf
241-mumnp-2005-form 3(17-04-2006).pdf
241-mumnp-2005-form 3(31-03-2005).pdf
241-mumnp-2005-form 5(17-04-2006).pdf
241-mumnp-2005-petition under rule 137(17-04-2006).pdf
241-mumnp-2005-petition under rule 138(17-04-2006).pdf
241-mumnp-2005-power of authority(31-03-2005).pdf
| Patent Number | 211311 | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Indian Patent Application Number | 241/MUMNP/2005 | ||||||||||||||||||
| PG Journal Number | 45/2007 | ||||||||||||||||||
| Publication Date | 09-Nov-2007 | ||||||||||||||||||
| Grant Date | 24-Oct-2007 | ||||||||||||||||||
| Date of Filing | 31-Mar-2005 | ||||||||||||||||||
| Name of Patentee | CYDEX, INC. | ||||||||||||||||||
| Applicant Address | SUITE 470, 12980 METCALF AVENUE, OVERLAND PARK, KS 66213, USA | ||||||||||||||||||
Inventors:
|
|||||||||||||||||||
| PCT International Classification Number | A61K31/735 C07H13/12 | ||||||||||||||||||
| PCT International Application Number | PCT/US00/00640 | ||||||||||||||||||
| PCT International Filing date | 2000-01-11 | ||||||||||||||||||
PCT Conventions:
|
|||||||||||||||||||