Title of Invention | HUMAN ANTIBODIES THAT BIND HUMAN IL-12 AND METHODS FOR PRODUCING |
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Abstract | Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity $i(in vitro) and $i(in vivo). An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the inveniton are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention. |
Full Text | N/A |
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in-pct-2001-01146-mum-claims(granted)-(12-11-2007).doc
in-pct-2001-01146-mum-claims(granted)-(12-11-2007).pdf
in-pct-2001-01146-mum-correspondence(26-09-2005).tif.pdf
IN-PCT-2001-01146-MUM-CORRESPONDENCE(26-5-2010).pdf
in-pct-2001-01146-mum-correspondence(ipo)-(23-01-2006).pdf
in-pct-2001-01146-mum-drawing(12-11-2007).pdf
in-pct-2001-01146-mum-form 1(28-09-2005).pdf
in-pct-2001-01146-mum-form 13(01-01-2008).pdf
in-pct-2001-01146-mum-form 13(23-02-2006).pdf
in-pct-2001-01146-mum-form 13(26-5-2010).pdf
in-pct-2001-01146-mum-form 19(17-05-2004).pdf
in-pct-2001-01146-mum-form 2(granted)-(12-11-2007).doc
in-pct-2001-01146-mum-form 2(granted)-(12-11-2007).pdf
in-pct-2001-01146-mum-form 24(01-03-2006).pdf
in-pct-2001-01146-mum-form 3(28-09-2005).pdf
in-pct-2001-01146-mum-form 4(23-02-2006).pdf
in-pct-2001-01146-mum-form 5(28-04-2005).pdf
in-pct-2001-01146-mum-form-pct-ipea-409(21-09-2001).pdf
in-pct-2001-01146-mum-form-pct-isa-210(12-11-2007).pdf
IN-PCT-2001-01146-MUM-OTHER DOCUMENT(26-5-2010).pdf
in-pct-2001-01146-mum-petition under rule 137(28-09-2005).pdf
in-pct-2001-01146-mum-power of attorney(26-05-2006).pdf
in-pct-2001-01146-mum-power of authority(26-05-2006).pdf
Patent Number | 213389 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Indian Patent Application Number | IN/PCT/2001/01146/MUM | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PG Journal Number | 04/2008 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Publication Date | 25-Jan-2008 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Grant Date | 01-Jan-2008 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Date of Filing | 21-Sep-2001 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Name of Patentee | KNOLL GMBH | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Applicant Address | KNOLLSTRASSE 50, D-67061 LUDWIGSHAFEN, | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Inventors:
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PCT International Classification Number | C07K 16/24 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PCT International Application Number | PCT/US00/07946 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PCT International Filing date | 2000-03-24 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PCT Conventions:
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