Title of Invention

A PROCESS FOR THE PREPARATION OF A CRYSTALLINE, POLYMORPHIC FORM OF A HEMISULPHATE SALT COMPOUND

Abstract

The present invention is concerned with a crystalline, polymorphic form of a compound of formula (I) characterised by a powder X-ray diffraction pattern obtained using copper K-alpha₁ radiation (Ƴ = 0.15046nm) which shows main peaks at 9.28, 10.38, 11.37, 12.40, 16.84, 17.46, 17.53, 17.78, 17.98, 19.48, 20.70, 21.29, 21.45, 22.21, 22.64, 23.08, 25.20 and 25.79. The invention also relates to processes for the preparation of said form, to pharmaceutical compositions containing same and to its use in medicine, particularly the treatment of conditions for which an agonist of 5-HT₁ receptors is indicated, for example, migraineThe present invention is concerned with a crystalline, polymorphic form of a compound of formula (I) characterised by a powder X-ray diffraction pattern obtained using copper K-alpha₁ radiation (Ƴ = 0.15046nm) which shows main peaks at 9.28, 10.38, 11.37, 12.40, 16.84, 17.46, 17.53, 17.78, 17.98, 19.48, 20.70, 21.29, 21.45, 22.21, 22.64, 23.08, 25.20 and 25.79. The invention also relates to processes for the preparation of said form, to pharmaceutical compositions containing same and to its use in medicine, particularly the treatment of conditions for which an agonist of 5-HT₁ receptors is indicated, for example, migraine

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Documents:

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in-pct-2001-01636-mum-cancelled pages(14-01-2005).pdf

in-pct-2001-01636-mum-cancelled pages(14-1-2005).pdf

in-pct-2001-01636-mum-claims(amended)-(14-1-2005).pdf

in-pct-2001-01636-mum-claims(amended)-(20-4-2005).pdf

in-pct-2001-01636-mum-claims(complete)-(21-12-2001).pdf

in-pct-2001-01636-mum-claims(granted)-(14-01-2005).doc

in-pct-2001-01636-mum-claims(granted)-(14-01-2005).pdf

in-pct-2001-01636-mum-claims(granted)-(9-1-2008).pdf

in-pct-2001-01636-mum-correspondence(03-08-2007).pdf

in-pct-2001-01636-mum-correspondence(2-1-2009).pdf

in-pct-2001-01636-mum-correspondence(ipo)-(18-2-2008).pdf

in-pct-2001-01636-mum-correspondence(ipo)-(20-04-2004).pdf

in-pct-2001-01636-mum-description(complete)-(21-12-2001).pdf

in-pct-2001-01636-mum-description(granted)-(9-1-2008).pdf

in-pct-2001-01636-mum-drawing(14-01-2005).pdf

in-pct-2001-01636-mum-drawing(14-1-2005).pdf

in-pct-2001-01636-mum-drawing(21-12-2001).pdf

in-pct-2001-01636-mum-drawing(9-1-2008).pdf

in-pct-2001-01636-mum-drawing(granted)-(9-1-2008).pdf

in-pct-2001-01636-mum-form 1(14-1-2005).pdf

in-pct-2001-01636-mum-form 1(21-12-2001).pdf

in-pct-2001-01636-mum-form 13(07-08-2007).pdf

in-pct-2001-01636-mum-form 13(7-8-2007).pdf

in-pct-2001-01636-mum-form 19(29-3-2004).pdf

in-pct-2001-01636-mum-form 1a(07-08-2007).pdf

in-pct-2001-01636-mum-form 1a(14-01-2005).pdf

in-pct-2001-01636-mum-form 2(complete)-(21-12-2001).pdf

in-pct-2001-01636-mum-form 2(granted)-(14-01-2005).doc

in-pct-2001-01636-mum-form 2(granted)-(14-01-2005).pdf

in-pct-2001-01636-mum-form 2(granted)-(9-1-2008).pdf

in-pct-2001-01636-mum-form 2(title page)-(complete)-(21-12-2001).pdf

in-pct-2001-01636-mum-form 2(title page)-(granted)-(9-1-2008).pdf

in-pct-2001-01636-mum-form 3(14-01-2005).pdf

in-pct-2001-01636-mum-form 3(21-12-2001).pdf

in-pct-2001-01636-mum-form 5(21-12-2001).pdf

in-pct-2001-01636-mum-form-pct-ipea-409(21-12-2001).pdf

in-pct-2001-01636-mum-general power of authority(21-12-2001).pdf

in-pct-2001-01636-mum-petition under rule 137(14-1-2005).pdf

in-pct-2001-01636-mum-petition under rule 138(14-01-2005).pdf

in-pct-2001-01636-mum-power of authority(14-01-2005).pdf

in-pct-2001-01636-mum-wo international publication report(21-12-2001).pdf