Title of Invention

PHENYL XANTHINE ESTERS AND AMIDES.

Abstract The present invention discloses complex exters and amides of phenyl xanthine derivatives of formula (I) or a solvate thereof wherein: X is -O- or -NH-; Q is (-CH2-)p7 (-CH=CH-)p7 (-C=C-)p where p is an integer of from 0 to 4; R1 is hydrogen or methyl; R2 and R3 independently represent O or S n is an integer of 1 to 50; and R is hydrogen or methyl. The present invention also provides processes for their preparation, pharmaceutical formulations comprising them, and their use in medicine, particularly in the prophylaxis and treatment of septic shock, inflammatory conditions, as well as immune disorders.
Full Text

Documents:

226-CAL-1998-FORM-27.pdf

226-cal-1998-granted-abstract.pdf

226-cal-1998-granted-claims.pdf

226-cal-1998-granted-correspondence.pdf

226-cal-1998-granted-description (complete).pdf

226-cal-1998-granted-form 1.pdf

226-cal-1998-granted-form 18.pdf

226-cal-1998-granted-form 3.pdf

226-cal-1998-granted-form 5.pdf

226-cal-1998-granted-gpa.pdf

226-cal-1998-granted-reply to examination report.pdf

226-cal-1998-granted-specification.pdf


Patent Number 218556
Indian Patent Application Number 226/CAL/1998
PG Journal Number 14/2008
Publication Date 04-Apr-2008
Grant Date 02-Apr-2008
Date of Filing 12-Feb-1998
Name of Patentee GLAXO GROUP LIMITED
Applicant Address GLAXO WELLCOME HOUSE, BERKELEY AVENUE, GREENFORD, MIDDX., UB6 0NN
Inventors:
# Inventor's Name Inventor's Address
1 SUSAN MARY DALUGE GLAXO WELLCOME INC., FIVE MOORE DRIVE, RESEARCH TRIANGLE PARK, NC 27709
2 GERALD WOLBERG 1109, TROON COURT, CARY, NC 27511
3 DOUGLAS ALAN LIVINGSTON ARRIS PHARMACEUTICAL, 1200 MAIN STREET, MONTANA, CA 94037
PCT International Classification Number A 61 K 31/522
PCT International Application Number N/A
PCT International Filing date
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 9703044.9 1997-02-14 U.K.