| Title of Invention | TRICYCLIC THROMBIN RECEPTOR ANTAGONISTS OF FORMULA I |
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| Abstract | Heterocyclic-substituted tricyclics of the formula or a pharmaceutically acceptable salt thereof,; wherein. the dotted line represents an optional single bond; represents an optional double bond; n is 0-2; Rio Q is R-substituted cycloalkyl, optionally additionally substituted by R13 and R is –NHCOOR16b, -NHCOR16b,-NHCONR4R5or-NHSO2R16 Het is a mono- or bicyclic optionally substituted and heteroaromatic group; 8 is a bond, alkylene, or optionally substituted alkenylene or alkynylene, wherein the remaining substituents are as defined in the specification, are disclosed, as well as pharmaceutical compositions containing them and a method of treating diseases associated with thrombosis, atherosclerosis, restenosis, hypertension, angina pectoris, arrhythmia, heart failure, and cancer by administering said compounds. Combination therapy with other cardiovascular agents is also claimed. |
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2291-chenp-2004 correspondence others.pdf
2291-chenp-2004 correspondence others.pdf
2291-chenp-2004 correspondence po.pdf
2291-chenp-2004 description (complete).pdf
| Patent Number | 218783 | ||||||||||||||||||||||||
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| Indian Patent Application Number | 2291/CHENP/2004 | ||||||||||||||||||||||||
| PG Journal Number | 21/2008 | ||||||||||||||||||||||||
| Publication Date | 23-May-2008 | ||||||||||||||||||||||||
| Grant Date | 16-Apr-2008 | ||||||||||||||||||||||||
| Date of Filing | 11-Oct-2004 | ||||||||||||||||||||||||
| Name of Patentee | SCHERING CORPORATION | ||||||||||||||||||||||||
| Applicant Address | 2000 Galloping Hill Road, Kenilworth, New Jersey 07033 - 0530, | ||||||||||||||||||||||||
Inventors:
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| PCT International Classification Number | C07D 05/06 | ||||||||||||||||||||||||
| PCT International Application Number | PCT/US2003/011510 | ||||||||||||||||||||||||
| PCT International Filing date | 2003-04-14 | ||||||||||||||||||||||||
PCT Conventions:
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