Title of Invention | PROCESS FOR PRODUCTION OF NUCLEOSIDE COMPOUND |
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Abstract | In reacting pentose-1-phosphoric acid with a nucleic acid base or a nucleic acid base analogue in an aqueous reaction medium in the presence of a metal cation to produce a nucleoside compound, the timing or method of addition of at least one of these components to the aqueous reaction medium is varied; thereby, a nucleoside compound can be produced at a high yield efficiently without inviting the high viscosity or solidification of the reaction mixture, even when the above components are used in such amounts that the reaction mixture becomes highly viscous or is solidified when the components are used without the above variation of the addition timing or method. Thus, there can be provided a process for producing a nucleoside compound, which comprises a step of reacting pentose-1-phosphoric acid with a nucleic acid base or a nucleic acid base analogue in the presence of nucleoside phosphorylase activity, which gives a nucleoside compound at an improved conversion, and which has wide applicability. |
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543-kolnp-2003-granted-abstract.pdf
543-kolnp-2003-granted-claims.pdf
543-kolnp-2003-granted-correspondence.pdf
543-kolnp-2003-granted-description (complete).pdf
543-kolnp-2003-granted-examination report.pdf
543-kolnp-2003-granted-form 1.pdf
543-kolnp-2003-granted-form 18.pdf
543-kolnp-2003-granted-form 2.pdf
543-kolnp-2003-granted-form 3.pdf
543-kolnp-2003-granted-form 5.pdf
543-kolnp-2003-granted-gpa.pdf
543-kolnp-2003-granted-letter patent.pdf
543-kolnp-2003-granted-priority document.pdf
543-kolnp-2003-granted-reply to examination report.pdf
543-kolnp-2003-granted-specification.pdf
543-kolnp-2003-granted-translated copy of priority document.pdf
Patent Number | 219523 | |||||||||||||||||||||||||||||||||
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Indian Patent Application Number | 543/KOLNP/2003 | |||||||||||||||||||||||||||||||||
PG Journal Number | 19/2008 | |||||||||||||||||||||||||||||||||
Publication Date | 09-May-2008 | |||||||||||||||||||||||||||||||||
Grant Date | 07-May-2008 | |||||||||||||||||||||||||||||||||
Date of Filing | 29-Apr-2003 | |||||||||||||||||||||||||||||||||
Name of Patentee | MITSUI CHEMICALS, INC. | |||||||||||||||||||||||||||||||||
Applicant Address | 2-5 KASUMIGASEKI 3-CHOME, CHIYODA-KU, TOKYO 100-6070 | |||||||||||||||||||||||||||||||||
Inventors:
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PCT International Classification Number | C 12 P 19/38 | |||||||||||||||||||||||||||||||||
PCT International Application Number | PCT/JP01/09701 | |||||||||||||||||||||||||||||||||
PCT International Filing date | 2001-11-06 | |||||||||||||||||||||||||||||||||
PCT Conventions:
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