| Title of Invention | DNA CODING FOR GLYCOPROTEIN VI AND EXPRESSED GLYCOPROTEIN VI. |
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| Abstract | TITLE: RECOMBINANT PLATELET COLLAGEN RECEPTOR GLYCOPROTEIN VI AND ITS PHARMACEUTICAL USE. The invention relates to Glycoprotein VI (GPVI), its isolation, purification, and methods for recombinant production. Especially, the invention relates to the use of GPVI, preferably recombinant GPVI, in the treatment of disorders and pathological events correlated directly or indirectly to blood coagulation disorders such as thrombotic and cardiovascular diseases. The extra cellular recombinant protein can also be used for establishing screening assays to find potential inhibitors of the membrane bound GPVI in order to inhibit binding of thrombocytes and platelets, respectively, to collagen. Changes in GPIV can be used to monitor platelet age and exposure to thrombotic and cardiovascular diseases. (FIG. nil) |
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in-pct-2001-1281-kol-granted-abstract.pdf
in-pct-2001-1281-kol-granted-assignment.pdf
in-pct-2001-1281-kol-granted-claims.pdf
in-pct-2001-1281-kol-granted-correspondence.pdf
in-pct-2001-1281-kol-granted-description (complete).pdf
in-pct-2001-1281-kol-granted-drawings.pdf
in-pct-2001-1281-kol-granted-examination report.pdf
in-pct-2001-1281-kol-granted-form 1.pdf
in-pct-2001-1281-kol-granted-form 18.pdf
in-pct-2001-1281-kol-granted-form 2.pdf
in-pct-2001-1281-kol-granted-form 3.pdf
in-pct-2001-1281-kol-granted-form 5.pdf
in-pct-2001-1281-kol-granted-form 6.pdf
in-pct-2001-1281-kol-granted-gpa.pdf
in-pct-2001-1281-kol-granted-letter patent.pdf
in-pct-2001-1281-kol-granted-reply to examination report.pdf
in-pct-2001-1281-kol-granted-sequence listing.pdf
in-pct-2001-1281-kol-granted-specification.pdf
in-pct-2001-1281-kol-granted-translated copy of priority document.pdf
| Patent Number | 219539 | ||||||||
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| Indian Patent Application Number | IN/PCT/2001/1281/KOL | ||||||||
| PG Journal Number | 19/2008 | ||||||||
| Publication Date | 09-May-2008 | ||||||||
| Grant Date | 07-May-2008 | ||||||||
| Date of Filing | 05-Dec-2001 | ||||||||
| Name of Patentee | AVENTIS PHARMA DEUTSCHLAND GMBH | ||||||||
| Applicant Address | 65926 FRANKFURT AM MAIN, DEUTSCHLAND, GERMANY. | ||||||||
Inventors:
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| PCT International Classification Number | C12N 15/12 | ||||||||
| PCT International Application Number | PCT/EP00/03683 | ||||||||
| PCT International Filing date | 2000-04-25 | ||||||||
PCT Conventions:
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