Title of Invention | HUMAN PAPILLOMAVIRUS POLYPEPTIDES AND IMMUNOGENIC COMPOSITIONS |
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Abstract | The present invention provides immunogenic and pharmaceutical compositions for the treatment and prevention of human papillomavirus (HPV)-associaled cancers and in particular, cervical cancer. In particular, this invention relates to fusion proteins, and the nucleic acids encoding these fusion proteins used to generate immune responses against HPV Specifically, this invention provides Tor fusions of HPV E6 and E7 in which the E6 and/or E7 contains one or more mutations .These mulations abrogate the transformation activity of these oncogenic proteins and, thus, confer safety to the E6/E7 fusions In addition, these fusions maintain or increase the immunogenic efficacy of E6 and E7 Any gene or protein delivery method can be used to deliver or package the immunogenic compositions of the present invention. |
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00505-kolnp-2005-assignment.pdf
00505-kolnp-2005-correspondence-1.1.pdf
00505-kolnp-2005-correspondence-1.2.pdf
00505-kolnp-2005-correspondence-1.3.pdf
00505-kolnp-2005-correspondence-1.4.pdf
00505-kolnp-2005-correspondence-1.5.pdf
00505-kolnp-2005-correspondence.pdf
00505-kolnp-2005-description(complete).pdf
00505-kolnp-2005-form-3-1.1.pdf
00505-kolnp-2005-form-3-1.2.pdf
00505-kolnp-2005-form-3-1.3.pdf
00505-kolnp-2005-international publication.pdf
00505-kolnp-2005-international search authority report.pdf
00505-kolnp-2005-others document.pdf
00505-kolnp-2005-pct others.pdf
00505-kolnp-2005-priority document.pdf
505-KOLNP-2005-(29-11-2005)-CORRESPONDENCE.pdf
505-KOLNP-2005-(29-11-2005)-PA.pdf
505-KOLNP-2005-CORRESPONDENCE 1.5.pdf
505-kolnp-2005-granted-abstract.pdf
505-kolnp-2005-granted-assignment.pdf
505-kolnp-2005-granted-claims.pdf
505-kolnp-2005-granted-correspondence.pdf
505-kolnp-2005-granted-description (complete).pdf
505-kolnp-2005-granted-drawings.pdf
505-kolnp-2005-granted-examination report.pdf
505-kolnp-2005-granted-form 1.pdf
505-kolnp-2005-granted-form 13.pdf
505-kolnp-2005-granted-form 18.pdf
505-kolnp-2005-granted-form 3.pdf
505-kolnp-2005-granted-form 5.pdf
505-kolnp-2005-granted-gpa.pdf
505-kolnp-2005-granted-letter patent.pdf
505-kolnp-2005-granted-reply to examination report.pdf
505-kolnp-2005-granted-sequence listing.pdf
505-kolnp-2005-granted-specification.pdf
505-KOLNP-2005-OTHERS PATENT DOCUMENTS.pdf
Patent Number | 220842 | |||||||||||||||
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Indian Patent Application Number | 505/KOLNP/2005 | |||||||||||||||
PG Journal Number | 23/2008 | |||||||||||||||
Publication Date | 06-Jun-2008 | |||||||||||||||
Grant Date | 06-Jun-2008 | |||||||||||||||
Date of Filing | 24-Mar-2005 | |||||||||||||||
Name of Patentee | WYETH HOLDINGS CORPORATION | |||||||||||||||
Applicant Address | FIVE GIRALDA FARMS, MADISON, NJ 07940 | |||||||||||||||
Inventors:
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PCT International Classification Number | A61K 38/00 | |||||||||||||||
PCT International Application Number | PCT/US2003/031726 | |||||||||||||||
PCT International Filing date | 2003-10-02 | |||||||||||||||
PCT Conventions:
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