| Title of Invention | A PROCESS FOR THE PREPARATION OF CITALOPRAM |
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| Abstract | There is described a process for the preparation of citalopram and of its pharmaceutically acceptable salts, which comprises treating a 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbaldoxime, O-substituted preferably with a diphenylmethyl or triphenylmethyl group, with formic-acetic anhydride. Furthermore, the total synthesis of citalopram, as free base or in form of its pharmaceutically acceptable salt, starting from 5-formylphthalide is described. (FIG. 1) |
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| Patent Number | 221097 | |||||||||
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| Indian Patent Application Number | 00132/KOLNP/2004 | |||||||||
| PG Journal Number | 25/2008 | |||||||||
| Publication Date | 20-Jun-2008 | |||||||||
| Grant Date | 18-Jun-2008 | |||||||||
| Date of Filing | 04-Feb-2004 | |||||||||
| Name of Patentee | INFOSINT S.A. | |||||||||
| Applicant Address | VIA CANTONALE 658A, CH-7745 POSCHIAVO | |||||||||
Inventors:
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| PCT International Classification Number | C07D 307/80 | |||||||||
| PCT International Application Number | PCT/EP02/08550 | |||||||||
| PCT International Filing date | 2002-07-29 | |||||||||
PCT Conventions:
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