Title of Invention

LIQUID GONADOTROPIN CONTAINING FORMULATIONS

Abstract The invention concerns a liquid gonadotropin-containing formulation characterised in that the formulation comprises a gonadotropin and stabilising amounts of a polycarboxylic acid or a salt thereof and of a thioether compound. The particular proteins (e.g. LH, TSH, FSH. or HCG) are in admixture with the particular stabilizers in an aqueous solution. The preparations contain a sufficient amount of the polycarboxylic acid or a salt thereof, preferably sodium citrate, and a sufficient amount of the thioether compound, preferably methionine, to stabilize the protein. The preparations preferably also include a nonreducing disaccharide like sucrose, and a non-ionic surfactant.
Full Text

Documents:

13-MAS-1998 ABSTRACT.pdf

13-MAS-1998 CLAIMS.pdf

13-MAS-1998 CORRESPONDENCE OTHERS.pdf

13-MAS-1998 CORRESPONDENCE PO.pdf

13-MAS-1998 DESCRIPTION (COMPLETE).pdf

13-MAS-1998 FORM-1.pdf

13-MAS-1998 FORM-19.pdf

13-MAS-1998 FORM-4.pdf

13-MAS-1998 FORM-5.pdf

13-MAS-1998 FORM-6.pdf

13-MAS-1998 PETITION.pdf

13-MAS-1998 POWER OF ATTORNEY.pdf


Patent Number 224609
Indian Patent Application Number 13/MAS/1998
PG Journal Number 49/2008
Publication Date 05-Dec-2008
Grant Date 21-Oct-2008
Date of Filing 02-Jan-1998
Name of Patentee AKZO NOBEL N.V
Applicant Address VELPERWEG 76, NL-6824 BM ARNHEM,
Inventors:
# Inventor's Name Inventor's Address
1 PETRUS, JOHANNES MARIA, VAN DEN, OFTERLAAR PLANTSOEN 1, 5384 ET HEESCH,
2 ARNOLD, TITUS PHILIP SKRABANJA WEEZENHOF 6209, 6536 AN NIJMEGEN,
PCT International Classification Number A61K38/24
PCT International Application Number N/A
PCT International Filing date
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 9720099.6 1997-01-15 EUROPEAN UNION