Title of Invention

PRODUCTION OF AMIDE DERIVATIVES AND INTERMEDIATES THEREOF

Abstract The present invention relates to (5R,S)-6-substituted amino-1 ,3-doxepan-5-ol derivative of the formula [V] wherein R<sup>1</sup> and R<sup>2</sup> are the same or different and each is a hydrogen atom, an alkyl or an aryl, or R<sup>1</sup> and R<sup>1</sup> cornbinedly fonn a cycloalkyl .ring together with the adjacent carbon atom, and R<sup>3</sup> is an aralkylamine residue or amino acid derivative residue having an (R) or (5) configuration, an enantiomer thereof or a salt thereof --- and a method of prodcuing the same. In addi tion, the novel intermediates of the present invention are extremely useful as intermediates for producing not only the aforementibned compound [XVI] but also compounds useful as X-ray contrast media.
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Documents:

1675-mas-1996 abstract.pdf

1675-mas-1996 claims granted.pdf

1675-mas-1996 correspondence others.pdf

1675-mas-1996 correspondence po.pdf

1675-mas-1996 description (complete) granted.pdf

1675-mas-1996 form-18.pdf

1675-mas-1996 form-2.pdf

1675-mas-1996 form-3.pdf

1675-mas-1996 form-4.pdf

1675-mas-1996 form-5.pdf

1675-mas-1996 petition.pdf

1675-mas-1996 power of attorney.pdf

1675-mas-1996abstract.jpg


Patent Number 224670
Indian Patent Application Number 1675/MAS/1996
PG Journal Number 49/2008
Publication Date 05-Dec-2008
Grant Date 21-Oct-2008
Date of Filing 23-Sep-1996
Name of Patentee AGOURON PHARMACEUTICALS INC
Applicant Address 10350 NORTH TORREY PINES ROAD, SUITE 100, LA JOLLA, CALIFORNIA 92037,
Inventors:
# Inventor's Name Inventor's Address
1 YASUKI YAMADA C/O. CENTRAL PHARMACEUTICAL RESEARCH INSTITUTE OF JAPAN TOBACCO INC., 1-1- MURASAKI-CHO, TAKATSUKI-SHI, OSAKA 569,
2 JAMES SHANLEY 4232 MT HUKEE AVENUE, SAN DIEGO, CA 92117,
3 MICHAEL DEASON 13826 FRAME ROAD, POWAY, CA 92064,
4 TAKASHI INABA C/O. CENTRAL PHARMACEUTICAL RESEARCH INSTITUTE OF JAPAN TOBACCO INC., 1-1- MURASAKI-CHO, TAKATSUKI-SHI, OSAKA 569,
PCT International Classification Number CO7C323/25
PCT International Application Number N/A
PCT International Filing date
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 248183/1995 1995-09-26 Japan