Title of Invention

DIRCTLY COMPRESSIBLE PHARMACEUTICAL ADJUVANT HAVING IMPROVED FUNCTIONALITY

Abstract This invention relates to directly comprissible adjuvant. More particularly, this invention relates to a particulate composition, which can be admixed with an active pharmaceutical material and,optionally, fillers, disintegrating agents and/or lubricants, and the resulting mixture can be directly compressed into a tablet without the necessity of gtanulation or slugging of the mixture. A process to prepare a co-processed directly compressible colloidal silicon dioxide based adjuvant is disclosed. The process discloses the novel use of colloidal silica. The process can be used to prepared the directly compressible adjuvat or drug or the process can be used prepare the tablets by wet granulation method. This invention relates to a pharmaceutical composition for use as a directly compressible adjuvate containing colloidal silicon dioxide and a process for making the same. A process is also disclosed for preparing acetaminophen agglomerates of the invention. Hence, the production is cost effective. The combination explored contains raw materials of pharmacopoeial grade. This directly compressible adjuvant is also useful as free-flowing filler for blending with dry powder ingrediants in dry-dosage capsules. The resulting tablet has a crushing strength of at least about 4 kilograms, preferable at least 6 kilograms, a friability loss of less than 1% by weight, and is capable of effectively disintegrating when places in water.
Full Text N/A

Documents:

668-mum-2002-cancelled pages(25-7-2003).pdf

668-mum-2002-claims(granted)-(25-7-2002).doc

668-mum-2002-claims(granted)-(25-7-2002).pdf

668-mum-2002-correspondence(18-3-2004).pdf

668-mum-2002-correspondence(ipo)-(10-7-2008).pdf

668-MUM-2002-CORRESPONDENCE(IPO)-(21-7-2008).pdf

668-mum-2002-form 1(25-7-2002).pdf

668-mum-2002-form 19(25-8-2003).pdf

668-mum-2002-form 2(granted)-(25-7-2002).doc

668-mum-2002-form 2(granted)-(25-7-2002).pdf

668-mum-2002-form 26(25-8-2003).pdf

668-mum-2002-form 3(25-7-2002).pdf


Patent Number 225930
Indian Patent Application Number 668/MUM/2002
PG Journal Number 07/2009
Publication Date 13-Feb-2009
Grant Date 03-Dec-2008
Date of Filing 25-Jul-2002
Name of Patentee PRANAV DHIRAJBHAI JOGANI
Applicant Address "Udit Apartments",Opp: Vitthalnagar, Shahibaug,Ahmedabad, 380 004
Inventors:
# Inventor's Name Inventor's Address
1 PRANAV DHIRAJBHAI JOGANI "Udit Apartments",Opp: Vitthalnagar, Shahibaug,Ahmedabad, 380 004
PCT International Classification Number A22C 13/00
PCT International Application Number N/A
PCT International Filing date
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 NA