Title of Invention | DIRCTLY COMPRESSIBLE PHARMACEUTICAL ADJUVANT HAVING IMPROVED FUNCTIONALITY |
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Abstract | This invention relates to directly comprissible adjuvant. More particularly, this invention relates to a particulate composition, which can be admixed with an active pharmaceutical material and,optionally, fillers, disintegrating agents and/or lubricants, and the resulting mixture can be directly compressed into a tablet without the necessity of gtanulation or slugging of the mixture. A process to prepare a co-processed directly compressible colloidal silicon dioxide based adjuvant is disclosed. The process discloses the novel use of colloidal silica. The process can be used to prepared the directly compressible adjuvat or drug or the process can be used prepare the tablets by wet granulation method. This invention relates to a pharmaceutical composition for use as a directly compressible adjuvate containing colloidal silicon dioxide and a process for making the same. A process is also disclosed for preparing acetaminophen agglomerates of the invention. Hence, the production is cost effective. The combination explored contains raw materials of pharmacopoeial grade. This directly compressible adjuvant is also useful as free-flowing filler for blending with dry powder ingrediants in dry-dosage capsules. The resulting tablet has a crushing strength of at least about 4 kilograms, preferable at least 6 kilograms, a friability loss of less than 1% by weight, and is capable of effectively disintegrating when places in water. |
Full Text | N/A |
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668-mum-2002-cancelled pages(25-7-2003).pdf
668-mum-2002-claims(granted)-(25-7-2002).doc
668-mum-2002-claims(granted)-(25-7-2002).pdf
668-mum-2002-correspondence(18-3-2004).pdf
668-mum-2002-correspondence(ipo)-(10-7-2008).pdf
668-MUM-2002-CORRESPONDENCE(IPO)-(21-7-2008).pdf
668-mum-2002-form 1(25-7-2002).pdf
668-mum-2002-form 19(25-8-2003).pdf
668-mum-2002-form 2(granted)-(25-7-2002).doc
668-mum-2002-form 2(granted)-(25-7-2002).pdf
668-mum-2002-form 26(25-8-2003).pdf
668-mum-2002-form 3(25-7-2002).pdf
Patent Number | 225930 | ||||||||
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Indian Patent Application Number | 668/MUM/2002 | ||||||||
PG Journal Number | 07/2009 | ||||||||
Publication Date | 13-Feb-2009 | ||||||||
Grant Date | 03-Dec-2008 | ||||||||
Date of Filing | 25-Jul-2002 | ||||||||
Name of Patentee | PRANAV DHIRAJBHAI JOGANI | ||||||||
Applicant Address | "Udit Apartments",Opp: Vitthalnagar, Shahibaug,Ahmedabad, 380 004 | ||||||||
Inventors:
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PCT International Classification Number | A22C 13/00 | ||||||||
PCT International Application Number | N/A | ||||||||
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PCT Conventions:
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