Title of Invention

A PROCESS FOR PREPARING OPTICALLY PURE (S,S)-2-(3-CHLOROPHENYL)-3,5,5-TRIMETHYL-2-MORPHOLINOL

Abstract The present invention relates to a process for preparing optically enriched (S,S)-hydroxybupropion, or a phannaceutically acceptable salt thereof, comprising: (a) contacting hydroxybupropion with optically pure camphoric acid, tartaric acid, malic acid or mandelic acid; or an optically pure derivative thereof: (b) isolating an optically enriched salt of (S,S)-hydroxybupropion; and (c) contacting the salt of (S,S)-hydroxybupropion with a base.
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Documents:

in-pct-2002-1487- form 1.pdf

in-pct-2002-1487- form 18.pdf

in-pct-2002-1487- form 3.pdf

in-pct-2002-1487- form 5.pdf

in-pct-2002-1487-che abstract.pdf

in-pct-2002-1487-che claims granted.pdf

in-pct-2002-1487-che correspondence others.pdf

in-pct-2002-1487-che correspondence po.pdf

in-pct-2002-1487-che descripetion (complete) granted.pdf

in-pct-2002-1487-che petition.pdf

in-pct-2002-1487-che power of attorney.pdf


Patent Number 226987
Indian Patent Application Number IN/PCT/2002/1487/CHE
PG Journal Number 07/2009
Publication Date 13-Feb-2009
Grant Date 31-Dec-2008
Date of Filing 19-Sep-2002
Name of Patentee SEPRACOR INC
Applicant Address 111 LOCKE DRIVE, MARLBOROUGH, MA 01752,
Inventors:
# Inventor's Name Inventor's Address
1 FANG, QUN, K 35 ATWOOD STREET, WELLESLEY, MA 02181,
2 SENANAYAKE, CHRISANTHA, H 11 OLD FARM CIRCLE, SHREWSBURY, MA 01545,
3 GROVER, PAUL 4 WARWICK ROAD, FRANKLIN, MA 02038,
PCT International Classification Number A61K31/5375
PCT International Application Number PCT/US00/23080
PCT International Filing date 2000-08-23
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 09/510,241 2000-02-22 U.S.A.
2 09/640,725 2000-08-18 U.S.A.