Title of Invention	PROCESS FOR THE PREPARATION OF ZOLPIDEM
Abstract	A novel process is disclosed for the preparation of imidazo [1,2- α] pyridine-3-acetic acid compounds and derivatives thereof, and more particularly Zolpidem. The process to prepare Zolpidem involves a “One pot” process for the conversion of 2-(4-methylphenyl)-6-methylimidazo [1,2- α] pyridine –3-acetic acid. The novelty of the present invention resides in part on (1) process being “One pot” avoids multi-step extractive work-up procedures and hence is a convenient process to follow even on plant scale affording overall high yields (2) preparation of Zolpidem from 2-(4-methylphenyl)-6-methylimidazo [1,2-α] pyridine-3-acetic acid by a mixed anhydride method using pivaloyl chloride.

Title of Invention

PROCESS FOR THE PREPARATION OF ZOLPIDEM

Abstract

A novel process is disclosed for the preparation of imidazo [1,2- α] pyridine-3-acetic acid compounds and derivatives thereof, and more particularly Zolpidem. The process to prepare Zolpidem involves a “One pot” process for the conversion of 2-(4-methylphenyl)-6-methylimidazo [1,2- α] pyridine –3-acetic acid. The novelty of the present invention resides in part on (1) process being “One pot” avoids multi-step extractive work-up procedures and hence is a convenient process to follow even on plant scale affording overall high yields (2) preparation of Zolpidem from 2-(4-methylphenyl)-6-methylimidazo [1,2-α] pyridine-3-acetic acid by a mixed anhydride method using pivaloyl chloride.

Full Text	N/A

Documents:

1081-mum-2003-abstract(27-10-2008).doc

1081-mum-2003-abstract(27-10-2008).pdf

1081-mum-2003-cancelled pages(27-10-2008).pdf

1081-MUM-2003-CLAIMS(27-10-2008).pdf

1081-mum-2003-claims(granted)-(27-10-2008).doc

1081-mum-2003-claims(granted)-(27-10-2008).pdf

1081-MUM-2003-CORRESPONDENCE(27-10-2008).pdf

1081-MUM-2003-CORRESPONDENCE(IPO)-(17-7-2008).pdf

1081-mum-2003-correspondence(ipo)-(27-01-2009).pdf

1081-MUM-2003-DESCRIPTION(COMPLETE)-(27-10-2008).pdf

1081-mum-2003-form 1(12-04-2004).pdf

1081-mum-2003-form 1(17-10-2003).pdf

1081-mum-2003-form 18(05-07-2007).pdf

1081-mum-2003-form 2(27-10-2008).pdf

1081-mum-2003-form 2(granted)-(27-10-2008).doc

1081-mum-2003-form 2(granted)-(27-10-2008).pdf

1081-mum-2003-form 3(12-04-2004).pdf

1081-mum-2003-form 5(12-04-2004).pdf

« Previous Patent

Next Patent »

Patent Number

228038

Indian Patent Application Number

1081/MUM/2003

PG Journal Number

10/2009

Publication Date

06-Mar-2009

Grant Date

27-Jan-2009

Date of Filing

17-Oct-2003

Name of Patentee

CADILA PHARMACEUTICALS LTD.

Applicant Address

CADILA CORPORATE CAMPUS, SARKHEJ-DHOLKA ROAD, BHAT, AHMEDABAD - 382210.

Inventors:

#	Inventor's Name	Inventor's Address
1	SANDEEP PANDURANG BHUJBAL	CADILA PHARMACEUTICALS LTD., "CADILA CORPORATE CAMPUS", SARKHEJ-DHOLKA ROAD, BHAT, AHMEDABAD - 382210.
2	J. VENKAT RAMAN	CADILA PHARMACEUTICALS LTD., "CADILA CORPORATE CAMPUS", SARKHEJ-DHOLKA ROAD, BHAT, AHMEDABAD - 382210.
3	BAKULESH MAFATLAL KHAMAR	201, "ASHADHA", VASUNDHARA COLONY, GULBAI TEKRA, ELLISBRIGE, AHMEDABAD - 380006.
4	INDRAVADAN AMBALAL MODI	CADILA PHARMACEUTICALS LTD., CADILA CORPORATE CAMPUS, SARKHEJ-DHOLKA ROAD, BHAT, AHMEDABAD - 382210.
5	SATISH MOHAN PISHAVE	CADILA PHARMACEUTICALS LTD., "CADILA CORPORATE CAMPUS", SARKHEJ-DHOLKA ROAD, BHAT, AHMEDABAD - 382210.

PCT International Classification Number

C07D471/04 A61K31/47

PCT International Application Number

N/A

PCT International Filing date

PCT Conventions:

#	PCT Application Number	Date of Convention	Priority Country
1			NA