Title of Invention

HALO DERIVATIVES OF 9-DEOXO-9A-AZA-9A-HOMERYTHROMYCIN A AND A PROCESS FOR PREPARING THE SAME

Abstract

The present invention relates to halo derivatives of 9a-N-(N'-arylcarbamoyl)- and 9a- N-(N'-arylthiocarbamoyl)-9-deoxo-9a-aza-9a-homoerythromycin A of the general formula (I) wherein R has the meaning of a substituted aryl group of the formula (II) wherein substituents a, b, c, d and e are the same or different and at least one of them has the ... meaning of halo, a (C<SUB>1</SUB>-C<SUB>6</SUB>)haloalkyl or a (C<SUB>1</SUB>-C<SUB>6</SUB>)haloalkoxy group, whereas the rema1mng ones have the meaning of hydrogen, halo, a (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl or a (C<SUB>1</SUB>-C<SUB>6</SUB>)alkoxy group, and X has the meaning of oxygen or sulfur, and pharmaceutically acceptable addition salts thereof with inorganic or organic acids, to a process for their preparation, to a process for the preparation of pharmaceutical compositions comprising them and to the use of these pharmaceutical compositions for the treatment or prevention of bacterial infections. 29

Full Text

Documents:

1662-che.rtf

2001-1662.rtf

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in-pct-2001-1662-che abstract.pdf

in-pct-2001-1662-che claims.pdf

in-pct-2001-1662-che correspondence others.pdf

in-pct-2001-1662-che correspondence po.pdf

in-pct-2001-1662-che description (complete).pdf

in-pct-2001-1662-che form-18.pdf

in-pct-2001-1662-che form-3.pdf

in-pct-2001-1662-che form-5.pdf

in-pct-2001-1662-che pct.pdf

in-pct-2001-1662-che petition.pdf

in-pct-2001-1662-che power of attoney.pdf