Title of Invention | PHARMACEUTICAL COMPOSITIONS COMPRISING VALSARTAN AND NEP INHIBITORS |
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Abstract | The invention relates a pharmaceutical composition comprising a combination of (i) the AT 1- antagonist valsartan or a pharmaceutically acceptable salt thereof and (ii) a NEP inhibitor or a pharmaceutically acceptable salt thereof and optionally a pharmaceutically acceptable carrier and to a method for the treatment or prevention of a condition or disease selected frem the group consisting of hypertension, heart failure such as (acute and chronic) congestive heart failure, left ventricular dysfunction .and hypertrophic cardiomyopathy, diabetic cardiac myopathy, supraventricular and ventricular arrhythmias, atrial fibrillation, atrial flutter, detrimental vascular remodeling, myocardial infarction and its sequelae, atherosclerosis, angina (whether unstable or stable), renal insufficiency (diabetic and non- diabetic), heart failure, angina pectoris, diabetes, secondary aldosteronism, primary and secondary pulmonary hypertension, renal failure conditions, such as diabetic nephropathy, glomerulonephritis, scleroderma, glomerular sclerosis, proteinuria of primary renal disease, and also renal vascular hypertension, diabetic retinopathy, the management of other: vascular disorders, such as migraine, peripheral vascular disease, Raynaud's disease, luminal hyperplasia, cognitive dysfunction (such as Alzheimer's), glaucoma and stroke, comprising administering a therapeutically effective amount of the pharmaceutical composition to a mammal in need thereof. |
Full Text | page not clear |
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1538-chenp-2004 abstract-duplicate.pdf
1538-chenp-2004 assignment.pdf
1538-chenp-2004 claims granted.pdf
1538-chenp-2004 claims-duplicate.pdf
1538-chenp-2004 correspondence-others.pdf
1538-chenp-2004 correspondence-po.pdf
1538-chenp-2004 description (complete)-duplicate.pdf
1538-chenp-2004 description (complete).pdf
1538-chenp-2004 pct search report.pdf
Patent Number | 229051 | |||||||||
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Indian Patent Application Number | 1538/CHENP/2004 | |||||||||
PG Journal Number | 12/2009 | |||||||||
Publication Date | 20-Mar-2009 | |||||||||
Grant Date | 13-Feb-2009 | |||||||||
Date of Filing | 09-Jul-2004 | |||||||||
Name of Patentee | NOVARTIS AG | |||||||||
Applicant Address | LICHTSTRASSE 35, CH-4056 BASEL, | |||||||||
Inventors:
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PCT International Classification Number | A61K31/41 | |||||||||
PCT International Application Number | PCT/EP03/00415 | |||||||||
PCT International Filing date | 2003-01-16 | |||||||||
PCT Conventions:
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