| Title of Invention | A PROCESS FOR PRODUCING A PHOSPHINE OXIDE |
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| Abstract | where Ph is phenyl, X<sup>1</sup> and X<sup>2</sup> are both hydrogen or X<sup>1</sup> and X<sup>2</sup> taken together are CH<sup>2</sup>, R<sup>1</sup> is a protecting group, R<sup>2</sup> is fluorine, hydrogen, or OR<sup>3</sup>, where R<sup>3</sup> is a protecting group, and the squiggly line represents a bond that results in the adjacent double bond being in either the E or Z configuration, involves: (a) chlorinating a compound of the formula: where X<sup>1</sup>, X<sup>2</sup>, R<sup>1</sup>, R<sup>2</sup>, and the squiggly line are as above, using triphosgene in the presence of an organic base to obtain the compound of the formula: where X<sup>1</sup>, X<sup>2</sup>, R<sup>1</sup>, R<sup>2</sup>, and the squiggly line are as above; " and (b) reacting the compound of formula 3 with a salt ofdiphenyl phosphine oxide to obtain the compound of formula 1. Each of the above steps (a) and (b) are individually useful. |
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0303-mas-2000 abstract-duplicate.pdf
0303-mas-2000 claims-duplicate.pdf
0303-mas-2000 correspondence-others.pdf
0303-mas-2000 correspondence-po.pdf
0303-mas-2000 description (complete)-duplicate.pdf
0303-mas-2000 description (complete).pdf
| Patent Number | 229145 | ||||||||
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| Indian Patent Application Number | 303/MAS/2000 | ||||||||
| PG Journal Number | 12/2009 | ||||||||
| Publication Date | 20-Mar-2009 | ||||||||
| Grant Date | 13-Feb-2009 | ||||||||
| Date of Filing | 20-Apr-2000 | ||||||||
| Name of Patentee | F. HOFFMANN-LA ROCHE AG | ||||||||
| Applicant Address | 124 GRENZACHERSTRASSE, CH-4070 BASLE, | ||||||||
Inventors:
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| PCT International Classification Number | CO7CAO1/00 | ||||||||
| PCT International Application Number | N/A | ||||||||
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