| Title of Invention | ACYLATED ARYLCYCLOALKYLAMINES |
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| Abstract | The present invention relates to acylated arylcycloalkylamines of the formula I, in which R<sup>1</sup>, R<sup>2</sup> and n have the meanings indicated in the claims. The compounds of formula I are valuable pharmacologically active compounds which are useful in the treatment of various disease states including cardiovascular disorders such as atherosclerosis, thrombosis, coronary artery disease, hypertension and cardiac in- sufficiency. They upregulate the expression of the enzyme endothelial nitric oxide (NO) synthase and can be applied in conditions in which an increased expression of said enzyme or an increased NO level or the normalization of a decreased NO level is desired. The invention furthermore relates to processes for the preparation of compounds of the formula I, their use, in particular as active ingredients in . pharmaceuticals, and pharmaceutical preparations comprising them. |
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3143-CHENP-2004 CORRESPONDENCE OTHERS.pdf
3143-CHENP-2004 CORRESPONDENCE PO.pdf
3143-CHENP-2004 DESCRIPTION (COMPLETE).pdf
3143-CHENP-2004 POWER OF ATTORNEY.pdf
| Patent Number | 229228 | ||||||||||||
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| Indian Patent Application Number | 3143/CHENP/2004 | ||||||||||||
| PG Journal Number | 12/2009 | ||||||||||||
| Publication Date | 20-Mar-2009 | ||||||||||||
| Grant Date | 13-Feb-2009 | ||||||||||||
| Date of Filing | 31-Dec-2004 | ||||||||||||
| Name of Patentee | SANOFI-AVENTIS DEUTSCHLAND GmbH | ||||||||||||
| Applicant Address | BRUNINGSTRASSE 50, D-65929 FRANKFURT AM MAIN, | ||||||||||||
Inventors:
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| PCT International Classification Number | C07C 233/58 | ||||||||||||
| PCT International Application Number | PCT/EP03/08104 | ||||||||||||
| PCT International Filing date | 2003-07-24 | ||||||||||||
PCT Conventions:
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