Title of Invention

A CHELATING AGENT AND A METHOD FOR THE PREPARATION OF RADIOLABELED BIOMOLECULE WITH THE SAME

Abstract The invention relates to a chelating agent of the general formula: wherein m is 1; X isNR<SUB>4</SUB> ; Y is NHR<SUB>5</SUB> or P(R<SUB>5</SUB> )<SUB>2</SUB> ; R<SUB>1</SUB> and R<SUB>3</SUB> are the same or different and are selected from H, alkyl or aryl; R<SUB>2</SUB> is H, COOH,NHR<SUB>6</SUB> or (CH<SUB>2</SUB> )<SUB>n</SUB> COOR<SUB>6</SUB> ; R<SUB>4</SUB> is H, alkyl, aryl, (CH<SUB>2</SUB> )<SUB>n</SUB> COOR<SUB>6</SUB> or (CH<SUB></SUB> )<SUB>n</SUB> OR<SUB>6</SUB>, R<SUB>5</SUB> is H, alkyl, aryl, (CH<SUB>2</SUB> )<SUB>n</SUB> COOR<SUB>6</SUB> or (CH<SUB>2</SUB> )<SUB>n</SUB> OR<SUB>6</SUB> R<SUB>6</SUB> is H, alkyl, aryl, or a biomolecule; ~ n is 1,2,3,4,5,6,7,8,9 or 10; and when R<SUB>1</SUB> =R<SUB>3</SUB> =CH<SUB>3</SUB> , R<SUB>2</SUB> , and R<SUB>5</SUB> are not all three H.
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Documents:

2650-chenp-2005 abstract-duplicate.pdf

2650-chenp-2005 abstract.pdf

2650-chenp-2005 claims-duplicate.pdf

2650-chenp-2005 claims.pdf

2650-chenp-2005 correspondence-others.pdf

2650-chenp-2005 correspondence-po.pdf

2650-chenp-2005 descripition(completed)-duplicate.pdf

2650-chenp-2005 descripition(completed).pdf

2650-chenp-2005 drawings-duplicate.pdf

2650-chenp-2005 drawings.pdf

2650-chenp-2005 form-1.pdf

2650-chenp-2005 form-18.pdf

2650-chenp-2005 form-26.pdf

2650-chenp-2005 form-3.pdf

2650-chenp-2005 form-5.pdf

2650-chenp-2005 pct.pdf

2650-chenp-2005 petition.pdf


Patent Number 229418
Indian Patent Application Number 2650/CHENP/2005
PG Journal Number 12/2009
Publication Date 20-Mar-2009
Grant Date 17-Feb-2009
Date of Filing 14-Oct-2005
Name of Patentee MALLINCKRODT INC
Applicant Address 675 McDonnell Boulevard, P.O. Box 5840, St. Louis, MO 63134,
Inventors:
# Inventor's Name Inventor's Address
1 SANTOS, Isabel, R Rua Cidade Benguela, Lote 257, 6 Dto, P-1800 Lisboa,
2 GALAMBA CORREIA, Joao, D Avenida Miguel Torga N 6, 3 C, P-1070-373 Lisboa,
3 ROCHA PAULO, Antonio, M Rua Actor Isidoro N 31, 2 Esq, P-1900 Lisboa,
4 ALVES, Susana Rua Dr Alberto De Araujo, N 14 - 5Dto, P-2800-310 Almada,
5 VITOR, Rute Rua Do Castelo N 6, Cv, Esq Pirescoxe, P-2685 Santa Iria Da Azoia,
PCT International Classification Number A61K51/04
PCT International Application Number PCT/US04/11685
PCT International Filing date 2004-04-15
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 03078217.1 2003-10-10 EUROPEAN UNION
2 03076106.8 2003-04-15 EUROPEAN UNION