Title of Invention

SYNERGISTIC COMBINATIONS OF MACROLIDE T-CELL MODULATOR OR IMMUNOSUPPRESSANT AND A RETINOID

Abstract The present invention relates to a pharmaceutical composition comprising 33- epichloro-33-desoxyascomycin in combination or association with a retinoid selected from the group of citretin, B-carotene, etretinate, isotretinoin, motretinide, retinal, retinoic acid, retinol, retinol palmitate, tamibaroten, adapalene, alitretinoin, bexarotene, and tazarotene, tqgether with at least one pharmaceutically acceptable diluent or carrier, and wherein the weight ratio of the 33-epichloro-33 desoxyascomycin is to retinoid is between 10:1 to 1:50. The present invention also relates to a process for the preparation of the same composition.
Full Text

Documents:

2498-CHENP-2005 ABSTRACT.pdf

2498-CHENP-2005 CLAIMS.pdf

2498-CHENP-2005 CORRESPONDENCE OTHERS.pdf

2498-CHENP-2005 CORRESPONDENCE PO.pdf

2498-CHENP-2005 DESCRIPTION (COMPLETE).pdf

2498-CHENP-2005 FORM-1.pdf

2498-CHENP-2005 FORM-18.pdf

2498-CHENP-2005 FORM-3.pdf

2498-CHENP-2005 FORM-5.pdf

2498-CHENP-2005 PCT.pdf

2498-CHENP-2005 PETITION.pdf

2498-CHENP-2005 POWER OF ATTORNEY.pdf


Patent Number 229723
Indian Patent Application Number 2498/CHENP/2005
PG Journal Number 13/2009
Publication Date 27-Mar-2009
Grant Date 19-Feb-2009
Date of Filing 03-Oct-2005
Name of Patentee NOVARTIS AG
Applicant Address Lichtstrasse 35, CH-4056 Basel,
Inventors:
# Inventor's Name Inventor's Address
1 SEKKAT, NABILA Davidsbodenstrasse 34, Ch - 4056 Basel,
2 PAUL, Carle 20, rue du Sundgau, F-68100 Mulhouse,
3 GRASSBERGER, Maximilian Schaumburgergasse 12/7, A-1040 Wien,
4 HIRSCH, Stefan Theodor-Heuss-Strasse 21A, 79539 Lorrach,
5 MAYER, Friedrich, Karl Im Ziegelgarten 9, CH-4104 Oberwil,
6 MEINGASSNER, Josef, Gottfried Max Margules Weg 10, A-2380 Perchtoldsdorf,
7 STUTZ, Anton Haymogasse 140, A-1238 Wien,
PCT International Classification Number A61K 31/05
PCT International Application Number PCT/EP04/03511
PCT International Filing date 2004-04-02
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 0307864.9 2003-04-04 U.K.