| Title of Invention | NEW CRYSTALLINE MODIFICATION OF 2-(3,5-BIS-TRIFLUOROMETHYL-PHENYL)-N-[6-(1,1-DIOXO1N6-THIOMORPHOLIN-4-YL)-4-(4-FLUORO-2-METHYL-PHENYL)-PYRIDIN-3-YL]-N-METHYL-ISOBUTYRAMIDE |
|---|---|
| Abstract | The present invention relates to a new crystalline modification of 2-(3,5-bis-trifluoromethyl-phenyl)-N-[6-(1,1-dioxo-1&lgr;6-thiomorpholin-4-yl)-4(4-fluoro-2-methyl-phenyl)-pyridin-3-yl]-N-methyl-isobutyramide characterized by the following X-ray diffraction pattern obtained with a CUK&agr; radiationat 2&thetas; (2Theta)= 4.5, 6.4, 7.5, 7.7, 8.0, 8.2, 10.0, 10.2, 10.9, 11.1, 12.9, 13.4, 14.0, 14.5, 15.1, 15.6, 16.2, 16.5, 17.3, 17.5, 18.0, 18.9, 19.3, 19.5, 19.9, 20.1, 20.6, 21.0, 21.4, 22.7, 23.1 and 23.6 and an infrared spectrum having sharp bands at 2925, 2845, 1637, 1604, 1484, 1395, 1375, 1285, 1230, 1172, 1125, 1082, 999, 943, 893, 863, 860, 782, 705, 684 cm-1, and wherein the extrapolated melting point (DSC) is 137.2°C. |
| Full Text |
|---|
1754-CHENP-2005 CORRESPONDENCE OTHERS.pdf
1754-CHENP-2005 CORRESPONDENCE PO.pdf
1754-CHENP-2005 DESCRIPTION (COMPLETE).pdf
1754-CHENP-2005 POWER OF ATTORNEY.pdf
| Patent Number | 230556 | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Indian Patent Application Number | 1754/CHENP/2005 | ||||||||||||||||||
| PG Journal Number | 13/2009 | ||||||||||||||||||
| Publication Date | 27-Mar-2009 | ||||||||||||||||||
| Grant Date | 27-Feb-2009 | ||||||||||||||||||
| Date of Filing | 29-Jul-2005 | ||||||||||||||||||
| Name of Patentee | F. HOFFMANN-LA ROCHE AG | ||||||||||||||||||
| Applicant Address | Grenzacherstrasse 124, CH-4070 Basel, | ||||||||||||||||||
Inventors:
|
|||||||||||||||||||
| PCT International Classification Number | A61K 31/54 | ||||||||||||||||||
| PCT International Application Number | PCT/EP2004/000547 | ||||||||||||||||||
| PCT International Filing date | 2004-01-23 | ||||||||||||||||||
PCT Conventions:
|
|||||||||||||||||||