Title of Invention

"DEVICE AND PROCESS FOR MANUFACTURING A PRODUCTS FROM STRIP TAPE"

Abstract

The present invention relate to a Device and Process for manufacturing a products from strip tape, such as a dermal or transdermal patch or another administration form for oral application, as well as fillable containers or sealed-margin bags comprising -a vacuum roll (4) which is provided for drawing off and separating the web of material (2), wherein said web of material (2) is held by negative pressure in the web-traveling zone, such that said web of material (2) can be served into individual strips (6) in cooperation with a circular knife roll (5),characterized in that a vacuum conveyer channel (12) is associated to each strip (6), said channel (12) being designed such that each strip (6) is turned of its way to the channel or through said channel (12) by about 90°, and the ends of all the take-up channels (12) being brought together at one site to form a unit and that there are provided guide means and transport means at that site for the further transport to a conversion equipment.

Full Text

Print show and process for manufacturing a product from strip tape, especially for manufacturing a medicinal and/or active substance-containing product as well as tillable containers or sealed-margin bags The invention relates to a process for manufacturing a product from strip tape, especially a medicinal and/or active substance-containing product such as, for example, dermal or transdermal patches or another administration form, for example for oral application, as well as tillable containers or sealed-margin bags, in which process there is used as starting material a broad, active agent-containing web of material, for instance of sheet-like materials and, in particular, of active substance-containing sheeting or sheet-like active substance, said process comprising at least two of the following steps: separating the broad web of material into individual, narrow strips and, if necessary, winding the strips in individual coils or jointly twisting the strips. unwinding individual coils or pairs of coils, as required, and assembling at least two strips at a time to form a strip web, or unwinding the strip web wound up from individual strips. processing the web of material to form a product made-up of strip tape, performing final process steps as, for instance, manufacturing the final product, forming the final application form, laminating the carrier material, segregating, packaging etc. For manufacturing the above-mentioned products, strip tape consisting of a plurality of individual strips is used. This tape is made by separating a coilof the starting material into individual strips, said coil having a width resulting from the number of strips multiplied by the width of the strips plus edge trimming. Typically, the resultant strips are wound on reels and are jointly unwound in the number as required and assembled to form webs of material having at least two layers. The manufacture of the stock reels is very labour-intensive, as is the winding and unwinding of the individual strips. It is possible, here, that the material - which may be an active substance-containing material or a medicinal substance - is stretched impermissibly, with the unavoidable elongation of the material having a negative effect on the dosing accuracy of the medicinal substance. It is the object of the present invention to provide a process and a device suitable for carrying out said process which overcome the aforementioned disadvantages, diffi-culties and technical limitations, and, in particular, enable the manufacture of a strip tape product, especially preferred an active substance-containing product, at reduced expenditure in respect of work and costs and without disadvantageous elongation of the material. To achieve this object in a process of the kind mentioned at the outset, it is proposed according to the invention that a roll of material with a broad web of the starting material be mounted, loosely rotatable, on a take-up mandrel, that the web of material be drawn, in its entire width and without subjecting the material to tensile stress, from the roll of material by means of a vacuum roll, or a device comprising two rolls, which unwinds the material gently from the material roll with one of the rolls simultaneously serving as a counter support to the cutting knifes; the material being separated in the process into individual strips in the negative pressure zone of the vacuum roll by rolling a multiple circular knife roll, that at the end of the negative pressure zone of the vacuum roll or of the pair of rolls, each strip be drawn from the said vacuum roll or pair of rolls and be introduced in a take-up channel and continuously conveyed therein my means of negative pressure, that in the process each strip is turned on its way to the channel or through the channel by about 90°, and that at the end of the channels the strips be led one upon the other, at least two at a time, and thereafter conveyed in a, preferably open, groove for further processing under completion to form the final product, to a conversion equipment where the products are finished. One embodiment of the process provides that for drawing the web of material and separating it into strips in cooperation with the multiple circular knife roll, there is used instead of a vacuum roll, a smooth stripping roll cooperating in a. zone where the web of material travels around the roll with a pressure roll and a guide roll. A device for the manufacture according to the present invention of a product from strip tape, especially of a medicinal and/or active substance-containing product such as, for example, a dermal or transdermal patch or another administration form, for example for oral application, as well as tillable containers or sealed-margin bags, especially for carrying out the process according to the invention, is characterized in that: as a means for drawing off and separating the web of material a vacuum roll is provided, in whose web-travelling zone the web of material, held by the negative pressure, can be severed into individual strips in cooperation with the multiple circular knife roll, to each strip there is associated a vacuum conveyor channel which is designed such that each strip is turned on its way to the channel or through the channel by about 90°, and the ends of all the take-up channels 12 are brought together at one site to form a unit and that at that site there are provided guide means and transport means for the further transport to a conversion equipment. One embodiment of the device according to the invention provides that as means for drawing the web of material and for transport during the separation into strips in co-operation with the multiple circular knife roll, there is provided instead of a vacuum roll, a smooth stripping roll arranged in a zone where the web of material travels around the roll and adapted to cooperate with a pressure roll and a guide roll. The process according to the invention and the device provided for carrying out the same overcome the afore-mentioned disadvantages, difficulties and technical limitations of the prior art and, in particular, enable the manufacture of medicinal and/or active substance-containing products at reduced expenditure in terms of work and costs without disadvantageous elongation of the starting material. In accordance with the present invention it relates to Device for manufacturing a products from strip tape, such as a dermal or transdermal patch or another administration form for oral application, as well as fillable containers or sealed-margin bags comprising -a vacuum roll (4) which is provided for drawing off and separating the web of material (2), wherein said web of material (2) is held by negative pressure in the web-traveling zone, such that said web of material (2) can be served into individual strips (6) in cooperation with a circular knife roll (5), V characterized in that -a vacuum conveyer channel (12) is associated to each strip (6), said channel (12) being designed such that each strip (6) is turned of its way to the channel or through said channel (12) by about 90°, and the ends of all the take-up channels (12) being brought together at one site to form a unit and that there are provided guide means and transport means at that site for the further transport to a conversion equipment. In accordance with the present invention it relates to Process for manufacturing a product from strip tape, such as a dermal or transdermal patch or another administration form for oral application, as well as fillable containers or sealed-margin bags, wherein -a web of material is separated into individual strips(6) -each strip (6) is introduced into a take-up channel (12) and continuously conveyed therein by negative pressure, -in the process, each strip (6) is turned on its way to the channel or through the channel by 90°, -the strip (6) are led one upon the other at the end of the take-up channels, and thereafter being conveyed in a, preferably open, groove for processing under completion to form the finished product in a conversion equipment where the products are finished. Further details, features and advantages of this invention will become apparent from the following explanation of an embodiment example which is schematically illustrated in the figures. The figures show: Fig. 1: a side view of the device Fig. 2: a plan view of the device according to Fig. 1 Fig. 3: a partial view of the device with vacuum transport channels disposed at the end of the device. Fig. 4: a view of the device in which a smooth stripping roll is provided instead of a vacuum roll. The part of the device represented in Fig. 1 shows rolls of material 1 with a web 2 of the starting material in a duplicate arrangement on both sides of a plane of symmetry x-x, said rolls 1 being mounted on take-up mandrels 3, as well as a duplicate arrangement of vacuum rolls 4, and circular knife rolls 5 rolling on said vacuum rolls 4 and the web of material 2 and having a plurality of parallelly disposed circular knifes. The same device is shown in Fig. 2 in plan view, with rolls of material 1, mounting mandrel 3, the material web 2, which can be uncoiled, vacuum rolls 4, circular knife rolls 5, and strips of material 6 cut from the web 2 and running off the said circular knife rolls 5 at the end of the vacuum zone. Fig. 3 shows, in part in side view and in part in plan view, a vacuum roll 4. However, this may also be a stripping roll 8 aided by a guide roll 11, from which strips 6, cut by a circular knife roll (not shown), are transported in the width of the original web of material 2. For linear take-off of a plurality of strips 6 there are provided vacuum conveyor channels 12, each formed, for example, between two cover plates 13 and 14. Finally, Fig. 4 shows an alternative embodiment of the device wherein as means for drawing the material web 2 and for transport thereof during separation of the web of material in strips 6 in cooperation with a multiple circular knife roll 5 there is provided instead of a vacuum roll a smooth stripping roll 8 which is arranged in a zone in which the material web 2 travels around the roll and is adapted so as to cooperate with a pressure roll 10 and a guide roll 11. The process and device are uncomplicated, reduce the expenditure of work and costs reqiiired heretofore, and enable the manufacture from strip tape of medicinal and/or active substance-containing products of various design, or of tillable containers or sealed-margin bags, while avoid-ing a disadvantageous elongation of the material, and, in particular, using a starting material in the form of sheet-like material, preferably a sheet-like active substance-containing administration form. The present invention thus constitutes an optimal solution to the task presented at the outset. We claim; 1. Process for manufacturing a product from strip tape, in particular a dermal or transdermal patch or another administration form for oral application, as well as fillable containers or sealed-margin bags, wherein a roll of material (1) with a broad web of material (2) is mounted, loosely rotatable, on a take-up mandrel (3), a web of material (2) is drawn off, in its entire width and without subjecting the material to tensile stress, from the roll of material (1) by means of a vacuum roll (4), and is separated in the process into individual strips (6) in the negative pressure zone of said vacuum roll (4) by rolling a multiple circular knife roll (5), at the end of the negative pressure zone of the vacuum roll (4), each strip (6) is drawn from said vacuum roll (4), characterized in that each strip is introduced into a take-up channel (12) and continuously conveyed therein by negative pressure, in the process, each strip (6) is turned on its way to the channel or through the channel (12) by about 90°, and at the end of the channels (12) the strips (6) are led upon the other, two or more at a time, and thereafter are conveyed in a, preferably open, groove for processing under completion to form the finished product in a conversion equipment where the products are finished. 2. Process as claimed in claim 1, wherein sheet-like materials are used as broad webs of material. 3. Process as claimed in claim 1, wherein active substance-containing sheet-like administration forms are used as broad webs of material. 4. Process as claimed in claim 1, wherein a smooth stripping roll (8) is used instead of a vacuum roll for drawing off the web of material (2) and separating the same into strips (6) in cooperation with a multiple circular knife roll (5), said stripping roll (8) which in a ]one in which the web of material (2) travels around the roll cooperates with a pressure roll (10) and a guide roll (11). 5. Device for manufacturing a product from strip tape, such as a dermal or transdermal patch or another administration form for oral application, as well as fillable containers or sealed-margin bags comprising a vacuum roll (4) which is provided for drawing off and separating the web of material (2), wherein said web of material (2) is held by negative pressure in the web-traveling zone, such that said web of material (2) can be served into individual strips (6) in cooperation with a circular knife roll (5), characterized in that a vacuum conveyer channel (12) is associated to each strip (6),said channel (12) being designed such that each strip (6) is turned of its way to the channel or through said channel (12) by about 90°, and the ends of all the take-up channels (12) being brought together at one site to form a unit and that there are provided guide means and transport means at that site for the further transport to a conversion equipment. 6. Device as claimed in claim 5, wherein a smooth stripping roll (8) is provided instead of a vacuum roll for drawing off the web of material (2) and for transport during the separation into strips (6) in cooperation with a multiple circular knife roll (5), said stripping roll (8) being arranged in a zone where said web of material (2) travels around the roll, and being adapted to cooperate with a pressure roll (1) and a guide roll (11). 7. Process for manufacturing a product from strip tape substantially as herein described with reference to the foregoing description and the accompanying tables and drawings. 8. Device for manufacturing a product from strip tape substantially as herein described with reference to the foregoing description and the accompanying tables and drawings.

Documents:

in-pct-2001-01111-del-abstract.pdf

in-pct-2001-01111-del-claims.pdf

in-pct-2001-01111-del-correspondence-others.pdf

in-pct-2001-01111-del-correspondence-po.pdf

in-pct-2001-01111-del-description (complete).pdf

in-pct-2001-01111-del-drawings.pdf

in-pct-2001-01111-del-form-1.pdf

in-pct-2001-01111-del-form-13.pdf

in-pct-2001-01111-del-form-19.pdf

in-pct-2001-01111-del-form-2.pdf

in-pct-2001-01111-del-form-3.pdf

in-pct-2001-01111-del-form-5.pdf

in-pct-2001-01111-del-gpa.pdf

in-pct-2001-01111-del-pct-210.pdf

in-pct-2001-01111-del-pct-409.pdf

in-pct-2001-01111-del-petition-137.pdf

in-pct-2001-01111-del-petition-138.pdf