| Title of Invention | A PROCESS FOR THE ENANTIOSELECTIVE SYNTHESIS OF A CHIRAL LACTONE |
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| Abstract | A process is described for the stereoselective synthesis of a chiral lactone which can be used as an intermediate in the synthesis of biotin. The process includes a reaction sequence in which a cyclic meso-carboxylic acid anhydride is converted with the aid of a chiral alcohol with ring opening into a dicarboxylic acid monoester. With respect to the dicarboxylic acid monoester obtained from the cyclic meso-carboxylic acid anhydride and the chiral alcohol, the reaction proceeds diastereoselectively. The reaction is performed in the presence of a specific catalyst improving the diastereomeric purity of the dicarboxylic acid monoester. |
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2694-CHENP-2005 CORRESPONDENCE OTHERS.pdf
2694-CHENP-2005 CORRESPONDENCE PO.pdf
2694-CHENP-2005 DESCRIPTION (COMPLETE).pdf
2694-CHENP-2005 POWER OF ATTORNEY.pdf
| Patent Number | 232224 | ||||||||
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| Indian Patent Application Number | 2694/CHENP/2005 | ||||||||
| PG Journal Number | 13/2009 | ||||||||
| Publication Date | 27-Mar-2009 | ||||||||
| Grant Date | 16-Mar-2009 | ||||||||
| Date of Filing | 19-Oct-2005 | ||||||||
| Name of Patentee | DSM IP Assets B.V | ||||||||
| Applicant Address | Het Overloon 1, NL-6411 TE Heerlen, | ||||||||
Inventors:
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| PCT International Classification Number | C07D | ||||||||
| PCT International Application Number | PCT/EP04/04172 | ||||||||
| PCT International Filing date | 2004-04-20 | ||||||||
PCT Conventions:
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