| Title of Invention | PH-SENSITIVE POLYMER |
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| Abstract | The present invention relates to a conjugate or complex of an pH-sensitive polymer with a pharmaceutically effective natural or synthetic biomolecule or an active pharmaceutical ingredient pH-sensitive polymer, characterized in that the pH- sensitive polymer is a (meth)acrylate copolymer composed of 20 to 65% by weight methacrylic acid units and 80 to 35% by weight units of C<SUB>1</SUB>- to C<SUB>18</SUB>-alkyl esters of (meth)acrylic acid, which has a molecular weight in the range from 1 000 to 50000 g/mol, and brings about at least 60% haemolysis at pH 5.5, and less than 5% haemolysis at pH 7.4, in a concentration of 150 µg/ml in a cytotoxicity test with human red blood cells. This invention also relates to a pH-sensitive polymer and a process to prepare the pH-sensitive polymer. |
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2434-chenp-2004 claims granted.pdf
2434-chenp-2004 correspondence others.pdf
2434-chenp-2004 correspondence po.pdf
2434-chenp-2004 description (complete) granted.pdf
2434-chenp-2004 power of attorney.pdf
| Patent Number | 232669 | ||||||||||||||||||
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| Indian Patent Application Number | 2434/CHENP/2004 | ||||||||||||||||||
| PG Journal Number | 13/2009 | ||||||||||||||||||
| Publication Date | 27-Mar-2009 | ||||||||||||||||||
| Grant Date | 20-Mar-2009 | ||||||||||||||||||
| Date of Filing | 27-Oct-2004 | ||||||||||||||||||
| Name of Patentee | ROHM GmbH & CO. KG | ||||||||||||||||||
| Applicant Address | Kirschenallee, D-64293 Darmstadt, | ||||||||||||||||||
Inventors:
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| PCT International Classification Number | C08F 220/46 | ||||||||||||||||||
| PCT International Application Number | PCT/EP2002/011791 | ||||||||||||||||||
| PCT International Filing date | 2002-10-22 | ||||||||||||||||||
PCT Conventions:
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