| Title of Invention | OIL IN WATER MICROEMULSION COMPOSITIONS FOR TRANSMUCOSAL ADMINISTRATION OF PROTEINS AND PEPTIDES AND PROCESS THEREOF |
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| Abstract | The present invention relates to novel microemulsion compositions for transmucosal administration of proteins and peptides and process thereof. The invention more particularly relates to oil in water microemulsion compositions of peptides like insulin comprising of a combination of hydrophobic and hydrophilic penetration enhancers where the hydrophobic penetration enhancer is in finely subdivided state of less than 200nm. The hydrophobic penetration enhancer constitutes the oily phase of the microemulsion and is resent in very low concentration. The microemulsions of this invention are thermodynamically stable and can be administered effectively by transmucosal route enhancing the permeation of drug through mucosa and thus improving the bioavailability and efficacy even at low doses. |
| Full Text | N/A |
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681-MUM-2004-ABSTRACT(12-3-2009).pdf
681-MUM-2004-ABSTRACT(22-9-2008).pdf
681-MUM-2004-ABSTRACT(24-6-2004).pdf
681-MUM-2004-ABSTRACT(5-2-2009).pdf
681-MUM-2004-ABSTRACT(GRANTED)-(30-3-2008).pdf
681-MUM-2004-CANCELLED PAGES(5-2-2009).pdf
681-MUM-2004-CLAIMS(22-9-2008).pdf
681-MUM-2004-CLAIMS(24-6-2004).pdf
681-MUM-2004-CLAIMS(5-2-2009).pdf
681-MUM-2004-CLAIMS(GRANTED)-(30-3-2008).pdf
681-MUM-2004-CORRESPONDENCE(12-3-2009).pdf
681-MUM-2004-CORRESPONDENCE(22-1-2009).pdf
681-MUM-2004-CORRESPONDENCE(22-9-2008).pdf
681-MUM-2004-CORRESPONDENCE(5-2-2009).pdf
681-MUM-2004-CORRESPONDENCE(6-3-2009).pdf
681-MUM-2004-CORRESPONDENCE(9-3-2009).pdf
681-MUM-2004-CORRESPONDENCE(IPO)-(3-4-2009).pdf
681-MUM-2004-DESCRIPTION(COMPLETE)-(12-3-2009).pdf
681-MUM-2004-DESCRIPTION(COMPLETE)-(22-9-2008).pdf
681-MUM-2004-DESCRIPTION(COMPLETE)-(24-6-2004).pdf
681-MUM-2004-DESCRIPTION(COMPLETE)-(5-2-2009).pdf
681-MUM-2004-DESCRIPTION(GRANTED)-(30-3-2008).pdf
681-MUM-2004-FORM 1(12-3-2009).pdf
681-MUM-2004-FORM 1(22-9-2008).pdf
681-MUM-2004-FORM 1(24-6-2004).pdf
681-MUM-2004-FORM 19(24-6-2004).pdf
681-mum-2004-form 2(12-3-2009).pdf
681-mum-2004-form 2(24-6-2004).pdf
681-mum-2004-form 2(5-2-2009).pdf
681-MUM-2004-FORM 2(COMPLETE)-(24-6-2004).pdf
681-MUM-2004-FORM 2(GRANTED)-(30-3-2008).pdf
681-MUM-2004-FORM 2(TITLE PAGE)-(12-3-2009).pdf
681-MUM-2004-FORM 2(TITLE PAGE)-(22-9-2008).pdf
681-MUM-2004-FORM 2(TITLE PAGE)-(24-6-2004).pdf
681-MUM-2004-FORM 2(TITLE PAGE)-(5-2-2009).pdf
681-MUM-2004-FORM 2(TITLE PAGE)-(GRANTED)-(30-3-2008).pdf
681-MUM-2004-FORM 3(22-9-2008).pdf
681-MUM-2004-FORM 3(24-6-2004).pdf
681-MUM-2004-POWER OF ATTORNEY(24-6-2004).pdf
| Patent Number | 233413 | ||||||||||||
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| Indian Patent Application Number | 681/MUM/2004 | ||||||||||||
| PG Journal Number | 14/2009 | ||||||||||||
| Publication Date | 03-Apr-2009 | ||||||||||||
| Grant Date | 30-Mar-2009 | ||||||||||||
| Date of Filing | 24-Jun-2004 | ||||||||||||
| Name of Patentee | THE DIRECTOR, INSTITUTE OF CHEMICAL TECHNOLOGY | ||||||||||||
| Applicant Address | Nathalal Parikh Marg Matunga, Mumbai. | ||||||||||||
Inventors:
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| PCT International Classification Number | A61K9/107 | ||||||||||||
| PCT International Application Number | N/A | ||||||||||||
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