Title of Invention

CURVED POSITIONING AND INSERTION INSTRUMENT FOR INSERTING A GUIDE WIRE INTO THE FEMUR

Abstract

A curved positioning and insertion instrument for inserting a guide wire (50) into the femur has a curved guide tube (2) with a distal end to be placed on the trochanter (41) and/or the medial a proximal end for inserting a guide wire (50). The instrument also has a holding arm (4) that links the guide tube (2) to a handle (5). A positioning hook fitted with at least one correction bore (7, 8, 9, 10, 12) for receiving the guide wire (50) or another guide wire is arranged at the distal end of the guide tube (2). This structure makes it possible to easily insert further or additional guide wires (50) relative to a reference guide wire (50).

Full Text

FORM 2THE PATENT ACT 1970(39 of 1970)&The Patents Rules, 2003 COMPLETE SPECIFICATION(See section 10 and rule 13) 1. CURVED POSITIONING AND INSERTION INSTRUMENT FOR INSERTING A GUIDE WIRE INTO THE FEMUR 2.(A) Synthes GmbH(b) SWITZERLAND(c) Eimattstrasse 3,CH-4436 Oberdorf,Switzerland The following specification particularly describes the invention and the manner in which it is to be performed. 1 The invention relates to a curved positioning and insertion instrument for inserting a guide wire into the femur for precise bone opening. Precise bone opening requires a reliable reference in position and direction which a surgeon with a drill or cutter can use as a guide. It is known that guide wires which are inserted (drilled or tapped) into the femur prior to drilling in order to guide the drill safely are used for this purpose. US-A-6074392 describes such a curved positioning and insertion instrument for inserting a guide wire into the femur, comprising a curved guide tube having a distal end for' placing on the trochanter and a proximal end for pushing in a guide wire, comprising a retaining arm for the connection between the guide tube and a handle. This design has been chosen because the insertion of a guide wire along a curve is advantageous-with regard to the anatomy of the human femora, and the tissue in the affected region is therefore impaired to a lesser extent during an operation. US-A-6074392 therefore describes an instrument design comprising a key element which consists of a curved guide tube for a curved guide wire. This guide wire is inserted into the bone and serves as a guide path for a hollow and flexible drill. The guide wire is mounted with the aid of a positioning and insertion instrument, the curved guide tube being mounted by means of a support part on a handle which can be properly held by the surgeon. The exact positioning of the guide tube 2 is implemented by means of X-rays or by direct inspection. After positioning, the guide wire is hammered in along the longitudinal axis of the bone or driven in in another manner. Thereafter, the insertion instrument is removed and the flexible drill or cutter is passed over the guide wire. After drilling is complete, everything is removed. However, the weak point of this solution is that there is no particular possibility for correction if the X-ray image shows that the guide wire is not optimally positioned. In a completely different design, for example according to US-A-5951561 a guide instrument which has the possibility of correction of guide wires is also described. However, this design consists of a bulky sheath which receives a rotary cylindrical component comprising a plurality of discs each having a plurality of holes, which have to be oriented concentrically with one another in a complicated production process and in addition provide no possibility for tapping a guide wire along a curve into the femur. To this extent, this design offers no improvement for a design according to the generic type. It is now the object of the invention to permit corrections by means of a simple device, the intention being to impair the tissue in the affected region as little as possible. For this reason, as already noted above, the person skilled in the* art will not * at all have used US-A-5951561 as prior art for achieving the present object. It is also comprehensible that US-A- 3 6074392 published in 1998 is itself a further development of US-A-5624447 published in 1997, while US-A-5951561 was published in the same year as US-A-6074392 and therefore followed another parallel route for setting guide wires. Further but less relevant documents relating to the prior art are US-A-4466429, US-A-3439671, US-A-5135527, US-A-5112336, US-A-4712541, US-Bl-6273892. In order to achieve the object, the inventor now presents a novel positioning and insertion instrument which comprises a handle which is arranged by means of a retaining arm on a curved guide tube. At the end thereof there is a positioning hook with, if appropriate, a guide bore which is oriented at an angle of 6° - 30°, preferably 7° - 20°, in particular about 8°, relative to the guide tube. In addition to this bore, various correction bores are present, according to an improved further development. Furthermore, a T-handle is reqired when the instrument according to the invention is used. The invention thus makes it possible to insert at least one guide wire which subsequently guides an opening drill. Instead of a T-handle or a motorised drilling or tapping drive, it is also possible to provide an impact head so that the guide wire can be hammered in. According to the invention, during use in practice, the guide tube is, if appropriate, first loaded with a reference guide wire. The handle of the positioning and insertion instrument is then aligned by visual inspection approximately parallel to the longitudinal 4 axis of the femur and with the extension of the intramedullary canal thereof. The positioning hook is placed on the trochanter and the nose of the hook is forced by pressure in the medial direction into 'the muscle (gluteus medius) , the reference guide wire being inserted parallel to the longitudinal axis of the femur. The instrument is removed. Thereafter, the guide tube of the positioning and insertion instrument is loaded with an opening guide wire and, according to this method of use, the guide bore in the positioning hook is pushed over the reference guide wire and thus once again placed on the trochanter. Because the guide bore in the positioning hook is set at about 8° the positioning' and insertion instrument becomes aligned accordingly in order to give the opening guide wire the correct angle. This procedure is carried out because it is more difficult to estimate a certain angle visually than a parallelism. If, however, the reference guide wire were to happen to fit the first time, it would also be possible to use it as an opening guide wire. As a rule, however, it is expected that a second guide wire has to be set as the opening guide wire. A number of embodiments without a guide bore dispenses with the insertion of the reference guide wire and ensures the placing of the positioning and insertion instrument at the correct site and angle by the particular characteristics of its positioning hook which are adapted to the anatomical conditions. The design of these hooks is therefore chosen so that, when gently pressed into the medial muscle and when placed on the trochanter, the hook comes to rest in the 5 optimum position for insertion of the opening guide wire in the majority of applications. The nose is designed so that it can be pressed into the medial muscle while protecting soft tissue. Its thickness is about 0.5-10mm, preferably about l-5mm and in particular about 2.5mm. The length between the centre of the guide tube and the tip of the nose of the positioning hook may vary, depending on the soft tissue situation, between about 10-30mm, preferably about 15-25mm, and is in particular about 20mm. The correction bores have a diameter of about l-5mm, preferably about 1.8-3.6 and in particular about 3.3mm. The receptacle for the guide tube is about 3-20mm, preferably about 6-10mm and in particular about 8mm. If the opening guide wire is also inserted into the trochanter, it is approximately at an optimum angle of about 8° relative to the reference guide wire in the frontal plane at its insertion point. X-ray images can now confirm whether the opening guide wire is in the correct position for implementing the opening. However, if it is, for example, too close to the lateral cortex there is according to the invention the possibility of a correction with the aid of the positioning and insertion instrument. This is then pushed with one of its correction bores over the reference or opening guide wire and a further/ previously loaded, opening guide wire is inserted in a new position into the trochanter. The old opening guide wire which was not correctly positioned can then be removed. If required, such a correction measure can be made on the basis of the only set reference guide wire by directly pushing a correction bore, instead of 6 the guide bore, onto the reference guide wire. Further developments of the invention are indicated in the figures and in the dependent patent claims/ Claim 10 describes a novel method improved compared with the prior art and intended for placing an opening guide wire. The list of reference numerals is part of the disclosure. The invention is explained in more detail schematically and by way of example on the basis of figures. The figures are described in relation to one another and as a whole. Identical reference numerals denote identical components, and reference numerals with different indices indicate functionally identical or similar components. Fig. 1 schematically shows the positioning and insertion instrument having a T-handle, guide wires and an opening drill; Fig. 2 schematically shows the positioning and insertion instrument with loaded guide wire; Fig. 3a schematically shows the positioning hook of the positioning and insertion instrument with its guide and correction bores and the nose for retention in the medial muscle in frontal view or anterior/posterior view. 7 Fig. 3b schematically shows the positioning hook of the positioning and insertion instrument with its guide and correction bores and the nose for retention in the medial muscle in view A according' to fig. 3a; Fig. 4 schematically shows the positioning and insertion instrument with guide wire and T-handle, placed on the trochanter and ready for drilling, in frontal view or anterior/posterior view; Fig.5 schematically shows the positioning and insertion instrument loaded with the opening guide wire and pushed over the reference guide wire; Fig. 6 schematically shows the positioning and insertion instrument with T-handle, loaded with the opening guide wire, moved over the reference guide wire and placed again on the trochanter and ready for drilling; Fig. 7 schematically shows the opening drill pushed over the opening guide wire and with T-handle ready for drilling; Fig. 8 schematically shows an X-ray image of the femur with inserted guide wire; Fig. 9 schematically shows an X-ray image of the femur with inserted reference guide wire and opening guide wire to be inserted; Fig. 10 schematically shows an X-ray image of the femur with inserted reference guide wire and inserted opening 8 guide wire; Fig. 11 schematically shows an X-ray image of the femur with inserted opening guide wire and without .or optionally with removed reference guide wire; Fig. 12 schematically shows an X-ray image of the femur with non-optimally positioned first opening guide wire and second opening guide wire for correction; Fig. 13 schematically shows an X-ray image of the femur with correctly set opening guide wire and Fig. 14 schematically shows an X-ray image of the femur with opening bore. Fig. 15a schematically shows the positioning hook of the positioning and insertion instrument without guide bore and with its correction bores and the nose for retention in the medial muscle in frontal view or anterior/posterior view; Fig. 15b schematically shows the positioning hook of the positioning and insertion instrument without guide bore and with its correction bores and the nose for retention in the medial muscle in view A according to fig. 15a; Fig. 16a schematically shows the positioning hook of the positioning and insertion instrument without guide bore and with its correction bores and the., nose for retention in the medial muscle in frontal view or anterior/posterior view; 9 Fig. 16b schematically shows the positioning hook of the positioning and insertion instrument without guide bore and with its' correction bores and the nose for retention in the medial muscle in view A according to fig. 16a; Fig. 17a schematically shows the positioning hook of the positioning and insertion instrument without guide bore and with its correction bores and the nose for retention in the medial muscle in frontal view or anterior/posterior view; Fig. 17b schematically shows the positioning hook of the positioning and insertion instrument without guide bore and with its correction bores and the nose for retention in the medial muscle in view A according to fig. 17a; Fig. 18a schematically shows the positioning hook of the positioning and insertion instrument without guide bore and with its correction bores and the nose for retention in the medial muscle in frontal view or anterior/posterior view; Fig. 18b schematically shows the positioning hook of the positioning and insertion instrument without guide bore and with its correction bores and the nose for retention in the medial muscle in view A according to fig. 18a; Fig. 19a schematically shows the positioning hook of the positioning and insertion instrument without guide 10 bore and with its (additional) correction bores and the nose for retention in the medial muscle in frontal view or anterior/posterior view; Fig. 19b schematically shows the positioning hook of the positioning and insertion instrument without guide bore and with its (additional) correction bores and the nose for retention in the medial muscle in view A according to fig. 19a. Fig. 1 shows the individual components which as a rule are required in using the instrument according to the invention. The positioning and insertion instrument 1 consists of- a curved guide tube 2, at the distal end of which a positioning hook 3 is arranged. The curvature of the guide tube 2 describes a radius of about 300 to 800mm, preferably 500 to 700mm, in particular about 600mm. The positioning hook 3 is formed in such a way that it is retained on the tip of the greater trochanter and the medial muscle. In the region of the proximal end of the guide tube 2, mounted approximately perpendicularly thereto, is a retaining arm 4 which then curves in order to run approximately parallel to the guide tube 2. A handle 5, the longitudinal axis of which is approximately parallel to a tangent to the guide tube 2 in the region of the positioning hook 3, is present at the end of the retaining arm 4. Furthermore, fig. 1 shows two guide wires 50 which are such that they can be inserted into the guide tube 2 and can be used either as reference guide wire 50a or as' ' opening guide" wire 50b. In addition -a hollow opening drill 20 is shown, which is formed in such a way that it can be passed over a guide wire 50 and can 11 be operated by a T-handle 30. Finally, fig. 1 shows the above mentioned T-handle 30 with a lever 32 and a grill chuck, which fits both onto the guide wires 50 and on to the opening drill 20.' Of course, motor-driven drilling and tapping drives are of course also possible as an alternative to the T-handle. Fig. 2 shows the positioning and insertion instrument 1 with a guide wire 50 loaded into the guide tube 2. The guide wire 50 can be inserted at the proximal or distal end of the positioning and insertion instrument 1, which leads to at least temporary curvature of the guide wire 50. Fig. 3a and fig. 3b show the positioning hook 3 of the positioning and insertion instrument 1, comprising a guide bore 6, which is set at an angle of about 8° in the nose 11 relative to the guide tube 2 and the central bore thereof. In addition to this bore, various correction bores are present, in particular an anterior/posterior correction bore 7, a medial correction bore 8, a posterior/anterior correction bore 9 and a lateral correction bore 10. Fig. 4 shows the positioning and insertion instrument 1 with a guide wire 50 lowered into the guide tube 2, which instrument is placed on the greater trochanter 41 of a femur 40. The characteristics of the positioning hook 3 ensure proper non slip positioning on the surface of the trochanter 41 and in the medial muscle 45.' The handlers of the positioning and insertion instrument 1 is aligned parallel to the longitudinal axis of the femur 40 and parallel to the extension of 12 the intramedullary canal thereof. The T-handle 30 is shown in the position in which it is capable of inserting the guide wire 50. Fig. 5 shows the positioning and insertion instrument 1 which is just being pushed along its guide bore 6 on the reference guide wire 50a already inserted into the trochanter 41 of the femur 40. The positioning and insertion instrument 1 or its guide tube 2 is loaded with an opening guide wire 50b. Fig. 6 shows the positioning and insertion instrument 1 which has been pushed through the guide bore 6 over the reference guide wire 50a already inserted into the trochanter 41 of the femur 40. The positioning and insertion instrument 1 is correctly positioned corresponding to the angle of about 8° in the frontal plane of the guide bore 6, in order to insert the already loaded opening guide wire 50b. The T-handle 30 is shown in the position in which it is capable of inserting the opening guide wire 50b. Fig. 7 shows the opening drill 20 when it has been pushed over the inserted opening guide wire 50b. The T-handle 30 is shown in the position in which it is capable of inserting the opening drill 20 into the trochanter 41 of the femur 40. Fig. 8 shows an X-ray image which shows the positioning hook 3 of the positioning and insertion instrument 1 arid a guide wire 50 loaded in the guide tube 2 and inserted into the trochanter 41 of the femur 40. Proper positioning by means of the characteristics of 13 the positioning hook 3 on the surface of the trochanter 41 is evident. The guide wire 50 has been inserted parallel to the longitudinal axis of the femur 40 and in the intramedullary canal thereof. Fig. 9 shows an X-ray image which shows the positioning hook 3 of the positioning and insertion instrument 1, which has been pushed via its guide bore 6 over the reference guide wire 50a already inserted into the trochanter 41 of the femur 40. The positioning and insertion instrument 1, is optimally correctly positioned, corresponding to the angle of about 8°, in the frontal plane of the guide bore 6, in order to insert the already loaded opening guide wire 50b. Fig. 10 shows an X-ray image which shows the reference guide wire 50a and opening guide wire 50b inserted into the trochanter 41 of the femur 40. The desired insertion angle 42 of about 8° between reference guide wire 50a and opening guide wire 50b is clearly recognisable. Fig. 11 shows an X-ray image which shows the remaining opening guide wire 50b optionally after removal of the reference guide wire 50a. In this example, the opening guide wire 50b is located too close to the lateral cortex to implement the opening and has to be corrected. Fig. 12 shows an X-ray image which shows the correction of the opening guide wire 50b. A second opening guide wire 50b is inserted into the trochanter 41 parallel to the guide wire 50b. 14 Fig. 13 shows an X-ray image which shows the corrected opening guide wire 50b after removal of the first opening guide wire 50b.' It' is now located optimally for implementing the opening by means of opening drill 20. Fig. 14 shows an X-ray image which shows the implemented opening 43 of the trochanter 41 of the femur 4 0. Fig. 15a and fig. 15b show the positioning hook 3 of the positioning and insertion instrument 1, which positioning- hook has no guide bore, comprising various correction bores, in particular an anterior/posterior correction bore 7, a medial correction bore 8, a posterior/anterior correction bore 9 and a lateral correction bore 10. In comparison with the variant shown in fig. 3a and fig. 3b, the nose 11 is also markedly thinner. Fig. 16a and fig. 16b show the positioning hook 3 of the positioning and insertion instrument 1, which positioning hook has no guide bore, comprising various correction bores, in particular an anterior/posterior correction bore 7, a medial correction bore 8, a posterior/anterior correction bore 9 and a lateral correction bore 10. In comparison with the variant shown in fig. 15a and fig. 15b, the nose 11 tapers somewhat more sharply and is longer. Fig. 17a and fig. 17b show the positioning hook 3 of the positioning and insertion instrument 1, which 15 positioning hook has no guide bore, comprising various correction bores, in particular an anterior/posterior correction bore 7, a medial correction bore 8, a posterior/anterior correction ' bore: 9 and a lateral correction bore 10. This variant differs in comparison with the variants shown in fig. 15a and fig. 15b, fig. 16a and fig, 16b, substantially through a smaller cross-sectional area. The correction bores are enclosed by the outer contour. Fig. 18a and fig. 18b show the positioning hook 3 of the positioning and insertion instrument 1, which positioning hook has no guide bore, comprising various correction . bores, in particular an anterior/posterior correction bore 7, a medial correction bore 8, a posterior/anterior correction bore 9 and a lateral correction bore 10. In comparison with the variant shown in fig. 17a and fig. 17b, the nose tapers somewhat more sharply and is longer. This variant differs in comparison with the variants shown in fig.. 15a and fig. 15b, fig. 16a and fig. 16b, substantially through a smaller cross-sectional area. The correction bores are enclosed by the outer contour. Fig. 19a and fig. 19b show the positioning hook 3 of the positioning and insertion instrument 1, which positioning hook has no guide bore, comprising various correction bores, in particular an anterior/posterior correction bore 7, a medial correction bore 8, a posterior/anterior correction bore 9, a lateral correction bore 10 and four additional correction bores. 16 List of reference numerals 1 - Positioning and insertion instrument 2 - Guide tube 3 - Positioning hook 4 - Retaining arm 5 - Handle 6 - Guide bore 7 - Anterior/posterior correction bore 8 - Medial correction bore 9 - Posterior/anterior correction bore 10 - Lateral correction bore 11 - Nose 12 - Additional correction bore 20 - Opening drill or cutter 30 - T-handle 31 - Drill chuck 32 - Lever 40 - Femur 41 - Trochanter 42 - Angle 43 - Opening 44 - Femur axis 45 - Medial muscle 50 - Guide wire 50a - Reference guide wire 50b - Opening guide wire 50bl - Further opening guide wire 17 We Claim, 1. Curved positioning and insertion instrument for inserting a guide wire {50} into the femur (40) , comprising a curved guide tube (2) having a distal end for placing on the trochanter (41) and/or the medial muscle (45) and a proximal end for insertion of the guide wire (50), comprising a retaining arm (4) for the connection between the guide tube (2) and the handle (5), characterized in that a positioning hook (3) is arranged at the distal end of the guide tube (2) and is equipped with at least one correction bore (7,8,9,10,12)for receiving the one guide wire (50) or another guide wire (50) . 2. Instrument according to Claim 1, characterized in that the positioning hook (3) has at least four’ preferably eight, correction bores (7,8,9,10,12) which are provided in particular on a concentric circle around the guide tube (2). 3. Instrument according to either of the preceding Claims, characterized in that the positioning hook (3) is equipped with at least one guide bore (6) for receiving the one guide wire (50) or another guide wire (50). 4. Instrument according to any of the preceding Claims, characterized in that the design of the positioning hook (3) is nose-shaped and is chosen so that, when placed on the trochanter (41) , it comes to rest in the optimum position for the 18 insertion of an opening guide wire (50b) into the femur (40). 5. Instrument according' to any of the preceding Claims, characterized in that the guide tube (2) as well as the guide bore (6) are formed in such a way that they can receive both a reference guide wire (50a) and an opening guide wire (50b). 6. Instrument according to any of the preceding Claims, characterized in that the positioning hook has at least one anterior/posterior (7) and/or one medial (8) and/or one posterior/anterior (9) and/or one lateral correction bore (10) in order to be able to tap or drill second or further opening guide wires (50bl) a certain distance away from the first opening guide wire (50b) into the femur (40) . 7. Instrument according to any of the preceding Claims, characterized in that the handle (5) is aligned in the insertion position substantially. parallel to the frontal femur axis (44) . 8. Instrument according to any of the preceding Claims, characterized in that the positioning hook (3) is firmly connected to the guide tube (2). 9. Instrument according to any of the preceding Claims, characterized in that the guide bore (6) extends at an angle (42) of 6°-30°, preferably T-20°, in particular about 8°, tangentially to the axis of the guide tube (2) in the region of its 19 distal end. 10. Instrument according to any of the preceding Claim's, characterized in that the correction bores (7) extend at an angle to the axis of the guide tube (2) . 11. Instrument according to any of the preceding Claims, characterized in that the positioning hook (3) has a particular non slip design for placing on the trochanter (41) . 12. Instrument according to any of the preceding Claims, characterized in that the positioning hook (3) has a rounded and narrow nose (11) which holds the positioning hook in the muscle tissue with protection of soft tissue. 13. Method for positioning an opening guide wire (50b) in an intramedullary canal of a femur (40) using an instrument according to any of the preceding Claims, characterized in that the guide tube (2) is loaded with a reference guide wire (50a), the handle (5) of the positioning and insertion instrument (1) is then aligned approximately parallel to the femur axis (44) and with the extension of the intramedullary canal of the femur (40) , the positioning hook (3) is placed on the trochanter (41) and pressed thereby with the nose (11) into the medial muscle (45) , the reference guide wire (50a) being inserted into the trochanter (41) parallel to the femur axis (44) and as far as possible in the centre of the 20 intramedullary canal, after which the positioning and insertion instrument (1) is removed, the guide tube (2) of the positioning and insertion instrument (1) is loaded with an opening guide wire (50b) and the guide bore in the positioning hook (3) is moved over the reference guide wire (50a) and thus placed again on the trochanter (41), the positioning and insertion instrument (1) accordingly being aligned in order to give the opening guide wire (50b) the correct angle, and in that, if the opening guide wire (50b) is however now not optimally positioned, a correction is carried out with the aid of the positioning and insertion instrument (1), said instrument then being pushed with one of its correction bores over the reference or opening guide wire (50b); and a further, previously loaded opening guide wire (50bl) being inserted in a new position into the trochanter (41) or into the femur (40). Method according to Claim 10, characterized in that the opening guide wire (50b) is present at its insertion point at an angle (42) of 6°-30°, preferably 7°-20°, in particular about 8° relative to the reference guide wire (50a). Method for positioning an opening guide wire (50b) in an intramedullary canal of a femur (50) using an instrument according to any of the preceding claims characterized in that the guide tube (2) of the positioning and insertion instrument (1) is loaded with an opening guide wire (50b), the positioning hook (3) is placed on the trochanter 21 (41) and is pressed thereby with the nose (11) into the medial muscle (45), the positioning and insertion instrument (1) being aligned, according to the design ' of its positioning hook ' (3) , for giving the opening guide wire (50b) the correct position and the correct angle and in that, if the opening guide wire (50b) is however now not optimally positioned a correction is carried out with the aid of the positioning and insertion instrument {1) , said instrument then being pushed with one of its correction bores over the opening guide wire (50b), and a further, previously loaded opening guide wire (50bl) being inserted in a new position into the trochanter (41) or into the femur (40) . Set of instruments according to any of Claims 1-12 for methods according to any of Claims 13-15, characterized in that a plurality of position hooks (3) having different characteristics are provided, from which a suitable instrument can be chosen depending on the characteristics of. trochanter and soft tissue. Instrument according to any of the preceding Claims, characterized in that the guide tube is curved with a radius of about 300 to 800mm, preferably 500 to 700mm, in particular about 600mm. Curved positioning and insertion instrument for inserting a guide wire into the femur as herein described forgoing description and figures. 22 Dated this 8th day of February 2006. 23 Abstract A curved positioning and insertion instrument for inserting a guide wire (50) into the femur has a curved guide tube (2) with a distal end to be placed .on the trochanter (41) and/or the medial muscle (45) and a proximal end for inserting a guide wire If (50). The instrument also has a holding arm (4) that links the guide tube (2) to a handle (5) . A positioning hook fitted with at least one correction bore (7, 8, 9, 10, 12) for receiving the guide wire (50) or another guide wire is arranged at the distal end of the guide tube (2) . This structure makes it possible to easily insert further or additional guide wires (50) relative to a reference guide wire (50) .

Documents:

161-mumnp-2006-abstract.doc

161-mumnp-2006-abstract.pdf

161-mumnp-2006-cancelled pages(9-2-2009).pdf

161-mumnp-2006-claims(granted)-(12-6-2009).pdf

161-mumnp-2006-claims.doc

161-mumnp-2006-claims.pdf

161-MUMNP-2006-CORRESPONDENCE(6-2-2009).pdf

161-mumnp-2006-correspondence(9-2-2009).pdf

161-mumnp-2006-correspondence(ipo)-(22-6-2009).pdf

161-mumnp-2006-correspondence-received-ver-040506.pdf

161-mumnp-2006-correspondence-received-ver-070306.pdf

161-mumnp-2006-correspondence-received-ver-080306.pdf

161-mumnp-2006-correspondence-received-ver-090206.pdf

161-mumnp-2006-correspondence-received-ver-140306.pdf

161-mumnp-2006-descripiton (complete).pdf

161-mumnp-2006-description(granted)-(12-6-2009).pdf

161-MUMNP-2006-DRAWING(GRANTED)-(12-6-2009).pdf

161-mumnp-2006-drawings.pdf

161-mumnp-2006-form 1(9-2-2009).pdf

161-mumnp-2006-form 18(19-2-2007).pdf

161-mumnp-2006-form 2(granted)-(12-6-2009).pdf

161-mumnp-2006-form 2(title page)-(10-2-2006).pdf

161-mumnp-2006-form 2(title page)-(granted)-(12-6-2009).pdf

161-mumnp-2006-form 3(10-2-2006).pdf

161-mumnp-2006-form 5(10-2-2006).pdf

161-mumnp-2006-form-1.pdf

161-mumnp-2006-form-13.pdf

161-mumnp-2006-form-2.doc

161-mumnp-2006-form-2.pdf

161-mumnp-2006-form-26.pdf

161-mumnp-2006-form-3.pdf

161-mumnp-2006-form-5.pdf

161-mumnp-2006-specification(amended)-(9-2-2009).pdf

161-mumnp-2006-wo international publication report(10-2-2006).pdf

abstract1.jpg