Title of Invention

A PHARMACEUTICAL COMPOSITION AND A METHOD FOR PROLIFERATING CARDIOMYOCYTES

Abstract The proliferation of cardiomyocytes is induced by expressing cyclin and CDK in the cardiomyocytes, and by suppressing the function or action of a Cip/Kip family protein or inhibiting the production of a Cip/Kip family protein or inhibniting the production of a Cip/Kip family protein. Among the Cip/Kip family proteins, it is preferable to suppress the function of p27 kipl or inhibniting the production thereof. As a recombinant vector to be used therefore, thjere is provided a vector comprising: (1) a cycling gene; (2) a cyclin-dependent kinase gene; and (3) one or a plurality selected from the group consisting of a gene encoding a factor that inhibits the function or action of a Cip/Kip family protein and a nucleic acid sequence that inhibits the production of Cip/Kip family protein.
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Documents:

2238-CHENP-2006 FORM-6 23-09-2010.pdf

2238-CHENP-2006 AMENDED PAGES OF SPECIFICATION 07-12-2011.pdf

2238-CHENP-2006 AMENDED CLAIMS 07-12-2011.pdf

2238-CHENP-2006 AMENDED CLAIMS 17-02-2012.pdf

2238-CHENP-2006 CORRESPONDENCE OTHERS 08-06-2011.pdf

2238-CHENP-2006 FORM-3 07-12-2011.pdf

2238-CHENP-2006 OTHER PATENT DOCUMENT 07-12-2011.pdf

2238-CHENP-2006 POWER OF ATTORNEY 23-09-2010.pdf

2238-CHENP-2006 ABSTRACT.pdf

2238-CHENP-2006 CLAIMS.pdf

2238-CHENP-2006 CORRESPONDENCE OTHERS 17-02-2012.pdf

2238-CHENP-2006 CORRESPONDENCE OTHERS.pdf

2238-CHENP-2006 CORRESPONDENCE PO.pdf

2238-CHENP-2006 DESCRIPTION (COMPLETE).pdf

2238-CHENP-2006 DRAWINGS.pdf

2238-CHENP-2006 EXAMINATION REPORT REPLY RECEIVED 07-12-2011.pdf

2238-CHENP-2006 FORM-1 07-12-2011.pdf

2238-CHENP-2006 FORM-13 24-08-2007.pdf

2238-CHENP-2006 FORM-18.pdf

2238-CHENP-2006 FORM-3.pdf

2238-CHENP-2006 FORM-5.pdf

2238-CHENP-2006 OTHERS.pdf

2238-CHENP-2006 POWER OF ATTORNEY 07-12-2011.pdf


Patent Number 251654
Indian Patent Application Number 2238/CHENP/2006
PG Journal Number 13/2012
Publication Date 30-Mar-2012
Grant Date 27-Mar-2012
Date of Filing 21-Jun-2006
Name of Patentee DAIICHI SANKYO COMPANY, LIMITED
Applicant Address 3-5-1, NIHONBASHI HONCHO, CHUO-KU, TOKYO 103-8426
Inventors:
# Inventor's Name Inventor's Address
1 ADACHI, Mimi 18-1, Higashinakano 2-chome, Nakano-ku, Tokyo 1640003
2 NAKAYAMA, Keiichi 11, Hakozaki 5-chome, Higashi-ku, Fukuoka-shi, Fukuoka 8120053
3 KITAJIMA, Shigetaka 13-9, Miyazaki 2-chome, Miyamae-ku, Kawasaki-shi, Kanagawa 2160053
4 TAKAGI, Hiromitsu 21-2, Okutenjin-cho 2-chome, Takatsuki-shi, Osaka 569-1118
PCT International Classification Number C12N5/08
PCT International Application Number PCT/JP2004/017274
PCT International Filing date 2004-11-19
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 2003-391708 2003-11-21 Japan
2 2004-246533 2004-08-26 Japan