Title of Invention | A PHARMACEUTICAL COMPOSITION AND A METHOD FOR PROLIFERATING CARDIOMYOCYTES |
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Abstract | The proliferation of cardiomyocytes is induced by expressing cyclin and CDK in the cardiomyocytes, and by suppressing the function or action of a Cip/Kip family protein or inhibiting the production of a Cip/Kip family protein or inhibniting the production of a Cip/Kip family protein. Among the Cip/Kip family proteins, it is preferable to suppress the function of p27 kipl or inhibniting the production thereof. As a recombinant vector to be used therefore, thjere is provided a vector comprising: (1) a cycling gene; (2) a cyclin-dependent kinase gene; and (3) one or a plurality selected from the group consisting of a gene encoding a factor that inhibits the function or action of a Cip/Kip family protein and a nucleic acid sequence that inhibits the production of Cip/Kip family protein. |
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2238-CHENP-2006 FORM-6 23-09-2010.pdf
2238-CHENP-2006 AMENDED PAGES OF SPECIFICATION 07-12-2011.pdf
2238-CHENP-2006 AMENDED CLAIMS 07-12-2011.pdf
2238-CHENP-2006 AMENDED CLAIMS 17-02-2012.pdf
2238-CHENP-2006 CORRESPONDENCE OTHERS 08-06-2011.pdf
2238-CHENP-2006 FORM-3 07-12-2011.pdf
2238-CHENP-2006 OTHER PATENT DOCUMENT 07-12-2011.pdf
2238-CHENP-2006 POWER OF ATTORNEY 23-09-2010.pdf
2238-CHENP-2006 CORRESPONDENCE OTHERS 17-02-2012.pdf
2238-CHENP-2006 CORRESPONDENCE OTHERS.pdf
2238-CHENP-2006 CORRESPONDENCE PO.pdf
2238-CHENP-2006 DESCRIPTION (COMPLETE).pdf
2238-CHENP-2006 EXAMINATION REPORT REPLY RECEIVED 07-12-2011.pdf
2238-CHENP-2006 FORM-1 07-12-2011.pdf
2238-CHENP-2006 FORM-13 24-08-2007.pdf
2238-CHENP-2006 POWER OF ATTORNEY 07-12-2011.pdf
Patent Number | 251654 | |||||||||||||||
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Indian Patent Application Number | 2238/CHENP/2006 | |||||||||||||||
PG Journal Number | 13/2012 | |||||||||||||||
Publication Date | 30-Mar-2012 | |||||||||||||||
Grant Date | 27-Mar-2012 | |||||||||||||||
Date of Filing | 21-Jun-2006 | |||||||||||||||
Name of Patentee | DAIICHI SANKYO COMPANY, LIMITED | |||||||||||||||
Applicant Address | 3-5-1, NIHONBASHI HONCHO, CHUO-KU, TOKYO 103-8426 | |||||||||||||||
Inventors:
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PCT International Classification Number | C12N5/08 | |||||||||||||||
PCT International Application Number | PCT/JP2004/017274 | |||||||||||||||
PCT International Filing date | 2004-11-19 | |||||||||||||||
PCT Conventions:
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