Title of Invention

"OIL-IN-WATER TYPE EMULSION COMPOSITION"

Abstract

The present invention provides an oil-in-water emulsified composition comprising fatty acid soap, the following ingredients (2)- (5) and (6) water. (2) Polyethylene glycol having an average molecular weight of 2000-25000 in the amount of 0.3-4.0 wt% of the composition, (3) One, two, or more of nonionic surfactants having a HLB of 10-17 in the amount of 0.1-5.0 wt%, (4) one, two, or more of nonionic surfactants having a HLB of 2-10 in the amount of 0.1-5.0 wt% of the composition, and (5) an oil ingredient comprising a solid or semisolid oil ingredient in the amount of 40-70 wt% of the composition. The object of the present invention is to provide an oil~in-water emulsified composition primarily or secondarily aiming at removing dirt that exhibits no stickiness, superior stability, and richness.

Full Text

FORM 2 THE PATENTS ACT, 1970 (39 of 1970) & THE PATENTS RULES, 2003 COMPLETE SPECIFICATION (See section 10, RuJe 13) OIL-IN-WATER TYPE EMULSION COMPOSITION; SHISEIDO COMPANY, LTD., A CORPORATION ORGANIZED AND EXISTING UNDER THE LAWS OF JAPAN WHOSE ADDRESS IS 5-5, GINZA 7-CHOME, CHUO-KU, TOKYO, 1048010, JAPAN THE FOLLOWING SPECIFICATION PARTICULARLY DESCRIBES THE INVENTION AND THE MANNER IN WHICH IT IS TO BE PERFORMED. 1 DESCRIPTION TECHNICAL FIELD The present invention relates to an oil-in-water emulsified composition; this composition is particularly suitable for use in cleansing creams or massage creams. BACKGROUND ART Among oil-in-water emulsified compositions used as external preparation compositions such as cosmetics, there are products that contain fatty acid soaps and aim primarily or secondarily for removing dirt such as cleansing creams and massage creams; the main focus in the development of such products is to maintain the oil-in-water emulsion system from the time of production to just before use, and destroy the emulsion with the hand pressure at the time of use to elute out the oil ingredients in the inner phase to manifest the cleansing effect and massage effect. 2 In these oil-in~water emulsified compositions, the rich sensation derived from the richness of the composition is an element that improves the value of the product. Conventionally, means such as increasing the ratio of the oil ingredients in the inner phase to the total amount and increasing the ratio of the semisolid oil ingredients are employed to give this richness. Patent Document 1: JP 2004-168736 A DISCLOSURE OF INVENTION TECHNICAL PROBLEM Based on the situation as described above, the object of the present invention is to provide an oil-in-water emulsified composition primarily or secondarily aiming at removing dirt that exhibits no stickiness, superior stability, and ri chness. Patent Document 1, which is a prior art technology related to the present invention, discloses a cleansing agent containing 50% or less of water, 1-60% of a polyhydroxy compound, and 1- 3 95% of an oil ingredient; said cleansing agent is a transparent, semi-transparent, or emulsoid cleansing agent in which the oil ingredient is gelated stably without adding a gelling agent. However, the cleansing agent of said prior art document is not an emulsified type so it is difficult to give a rich sensation. Furthermore, said prior art document does not use polyethylene glycol, which is an essential ingredient in the present invention. TECHNICAL SOLUTION The inventor discovered that the problem described above could be solved by adding polyethylene glycol having a specified range of molecular weight to an oil-in-water emulsified composition primarily or secondarily aiming at removing dirt and maintaining other conditions in specified ranges, and thus completed the present invention. That is, the present invention provides an oil-in-water emulsified composition comprising (1) fatty acid soap, the following ingredients (2)-(5) 4 and (6) water (hereafter also referred to as "this emulsified composition"). (2) polyethylene glycol having an average molecular weight of 2000-25000 in the amount of 0.3-4.0 wt% of the composition, (3) one, two, or more of nonionic surfactants having a HLB of 10-17 in the amount of 0.1-5.0 wt% of the composition, (4) one, two, or more of nonionic surfactants having a HLB of 2-10 in the amount of 0.1-5.0 wt% of the composition, and (5) an oil ingredient comprising a solid or semisolid oil ingredient in the amount of 40-70 wt% of the composition. Also, the present invention provides the oil-in-water emulsified composition wherein the solid or semisolid oil ingredient content in said emulsified composition is 5.0-50 wt% of the total amount of the oil ingredients. Furthermore, the present invention provides the oil-in-water emulsified composition wherein said emulsified composition is a cleansing cream 5 or massage cream. ADVANTAGEOUS EFFECTS The present invention provides an oil-in-water emulsified composition primarily or secondarily aiming at removing dirt that exhibits no stickiness, superior stability, and richness. BEST MODE FOR CARRYING OUT THE INVENTION "Essential ingredients of the emulsified composition" (1) Fatty acid soap This emulsified composition can contain one, two or more types of fatty acid soaps regardless of the type as long as they are fatty acid soaps that can be used for external preparations; the fatty acid portion of said fatty acid soap usually has 12-22 carbon atoms, preferably 16-20. In the manufacturing process of this emulsified composition, said fatty acid soap is prepared by separately adding the fatty acid that is to be the fatty acid group of said fatty acid soap and the alkali agent (saponifying agent) to the system so 6 they coexist: said fatty acid is saponified by said alkali agent to generate the fatty acid soap. Examples of said alkali agent include potassium hydroxide, triethanolamine, diethanolamine, basic amino acids, borax, ammonia, taurate, and n-methy 1 taurate. Examples of the fatty acid soap that is added to this emulsified composition include sodium laurate, sodium myristate, sodium palmitate, sodium stearate, sodium oleate, potassium laurate, potassium myristate, potassium palmitate, potassium stearate, potassium oleate, monoethanolamine laurate, monoethanolamine myristate, monoethanolamine palmitate, and monoethanolamine stearate. The blend ratio of the fatty acid soap thus added to this emulsified composition is not limited in particular and can be chosen according to the specific form of this emulsified composition and other ingredients; generally, the fatty acid soap has 12-22 .carbon atoms and the blend ratio is 0.3-3.0 wt% of the composition, and preferably the fatty acid soap has 16-20 carbon 7 atoms and the blend ratio is approximately 0.5-2.0 wt% of the composition. (2) Polyethylene glycol This emulsified composition is required to contain polyethylene glycol having an average molecular weight of 2000-25000 (hereafter also referred to as "the specific high molecular weight polyethylene glycol"). If said average molecular weight is less than 2000, then it becomes hard for the composition to give a rich sensation; if it is over 25000, then emulsificat ion becomes difficult and the formulation tends to be unstable. One, two or more types of the specific high molecular weight polyethylene glycol are added to this emulsified composition; the blend ratio is 0.3-4.0 wt%, preferably 0.5-3.0 wt%, of the composition. If the blend ratio is less than 0.3 wt% of the composition, then it becomes hard for the composition to give a rich sensation; if it is over 4.0 wt%, then there is a strong tendency for the emulsification stability to decrease. (3) Hydrophilic nonionic surfactant 8 One, two or more types of nonionic surfactants having a HLB of 10-17 are added to this emulsified composition; the blend ratio is 0.1-5.0 wt%, preferably 0.5-3.0 wt%, of the composition. If the blend ratio is outside of this range, the combination balance with the lipophilic nonionic surfactant, described later, becomes poor and there is a stronger tendency for the emulsificat ion stability to decrease. Selection of said hydrophilic nonionic surfactant is not limited in particular; examples include POE (10-40) glyceryl monostearate, hexaglyceryl monolaurate, decaglyceryl monolaurate, decaglyceryl monomyristate, decaglyceryl monostearate, decaglyceryl monooleate, POE (40-60) castor oil, POE (30-100) hydrogenated castor oil, PEG (40-60) glyceryl triisostearate, PEG (10-60) glyceryl isostearate, PGE (40-60) glyceryl trioleate, PEG (40-60) hydrogenated castor oil isostearate, PEG-60 hydrogenated castor oil triisostearate, PEG (40-60) hydrogenated castor oil laurate, POE (7-20) cetyl ether, and POE (10-50) ol ey 1 ether. 9 (4) Lipophilic nonionic surfactant One, two or more types of nonionic surfactants having a HLB of 2-10 are added to this emulsified composition; the blend ratio is 0.1-5.0 wt%, preferably 0.5-3.0 wt%, of the composition. If the blend ratio is outside of this range, the combination balance with the aforementioned hydrophilic nonionic surfactant becomes poor and there is a stronger tendency for the emulsificat ion stability to decrease. Selection of said lipophilic nonionic surfactant is not limited in particular; examples include POE (3) oleyl ether, POE (3) lauryl ether, diglyceryl monostearate, decaglyceryl pentastearate, hexaglyceryl tristearate, POE (2) nonylphenyl ether, glyceryl palmitate, glyceryl isostearate, propylene glycol stearate, PEG (5-7) hydrogenated castor oil, PEG (5-20) glyceryl triisostearate, PEG (3-8) glyceryl isostearate, PEG (3-15) glyceryl tristearate, PEG (5-10) glyceryl trioleate, PEG (10-40) hydrogenated castor oil triisostearate, PEG (5-30) hydrogenated castor oil isostearate, POE sorbitol stearate, POE sorbitol isostearate, and POE sorbitol oleate. 10 r (5) Oil phase ingredients (sometimes simply referred to as "the oil phase" in this specification) This emulsified composition has the oil phase ingredients in the amount of 40-70 wt% of the composition. Here, the oil phase ingredients stand for the totality of the ingredients added as the oil phase when manufacturing the oil-in-water emulsified composition; specifically they are mainly oil ingredients (liquid oil ingredients, semisolid oil ingredients, and solid oil ingredients), surfactants (liquid surfactants, semisolid surfactants, and solid surfactants), and fatty acids. In addition to the ingredients mentioned above, oil soluble preservatives, ultraviolet absorbents, oil soluble drugs, antioxidants, and perfumes may be added. If the oil phase is less than 40 wt% of the composition, then the stability is satisfactory, but the makeup does not come off well and the composition tends to resist spreading; if it is more than 70 wt%, then the stability is poor and stickiness is felt during use. 11 For this emulsified composition, the aforementioned oil phase ingredients are required to contain solid or semisolid oil ingredients. A "solid or semisolid oil ingredient" refers to an oil ingredient whose melting point is room temperature (about 20~25°C) or higher; specific examples include waxes such as candelilla wax, beeswax, cotton wax, carnauba wax, bayberry wax, tree wax, montan wax, bran wax, lanolin, reduced lanolin, hard lanolin, kapok wax, sugar cane wax, jojoba wax, and shellac wax; higher alcohols that are solid at room temperature such as cetyl alcohol and stearyl alcohol; and solid oil ingredients such as cacao oil, hydrogenated castor oil, Japanese core oil, and shea butter. The blend ratio of the solid or semisolid oil ingredients in the oil phase of this emulsified composition is 5.0-50 wt%, preferably 10-35 wt%, of the total amount of the oil phase. If the ratio of the solid or semisolid oil ingredients is less than 5.0 wt% of the total amount of the oil phase, then the richness of the cream tends to decrease; if it is over 50 wt%, 12 then the stability decreases and stickiness is felt dur ing use. As described above, in addition to the aforementioned solid or semisolid oil ingredients, it is possible to add a liquid oil ingredient that is liquid at room temperature (as described above) as a constituent ingredient of the oil phase. Selection of the liquid oil ingredient is not limited in particular'» examples include liquid oils and fats such as linseed oil, tsubaki oil, macadamia nut oil, corn oil, olive oil, avocado oil, sasanqua oil, castor oil, safflower oil, apricot kernel oil, cinnamon oil, jojoba oil, grape oil, almond oil, rapeseed oil, sesame oil, sunflower oil, wheat germ oil, rice germ oil, rice bran oil, cotton seed oil, soybean oil, peanut oil, tea seed oil, evening primrose oil, egg yolk oil, liver oil, triglycerin, glyceryl trioctanoate, and glyceryl triisopalmitate ; octanoic esters such as cetyl octanoate! isooctanoic esters such as glyceryl tri-2-ethylhexaenoate and pentaerythritol tetra-2-ethylhexanoate; lauric esters such as hexyl laurate! myristic esters such as isopropyl myristate and octyldodecyl myristate; palmitic 13 esters such as octyl palmitate; isostearic esters such as isocetyl stearate; isostearic esters such as isopropyl isostearate; isopalmitic esters such as octyl isopalmitate; oleic esters such as isodecyl oleateJ adipic diesters such as diisopropyl adipate; sebacic diesters such as diethyl sabacate; and ester oils such as diisostearyl malatel and liquid hydrocarbon oils such as liquid paraffin and squalane. Furthermore, for the silicone oil, it is possible to use chain silicones such as dimethylpolysiloxane, methylphenylpolysiloxane, and methyhydrogenpolysiloxane; cyclic silicones such as octame thy 1 eye 1otetrasi1oxane, decamethylcyclopentasiloxane, and dodecamethyleye 1ohexasiloxane; silicone resins capable of forming a three dimensional network structure such as amino-modified silicone oil, polyether-modified silicone oil, carboxy-modified silicone oil, alky1-modified silicone oil, ammonium salt-modified silicone oil, fluorine-modified silicone oil, and trim.ethylsi.loxy si 1 icic acid; high polymer me thylpolysi1oxane such as high polymer dimethylpolysiloxane, high polymer 14 methylphenylpolysi1oxane, and high polymer methylvinylpolysi1oxane; and high polymer amino-modified methylpolysiloxane. Also, for the silicone surfactant, it is possible to add dimethicone polyol and such. (6) Water n- ratio wt%. This emulsified composition is an oil~i water type emulsified composition and it is essential for it to contain water. The blend is the balance of the ingredients other than water; it is generally in the range of 10-50 "General ingredients of this emulsified compos i tion* In addition to the aforementioned essential ingredients, general ingredients used in external preparations such as cosmetics can be added to this emulsified composition within the qualitative or quantitative range that does not affect the effect of the present invention. Examples of said general ingredients include surfactants other than those described above, powders, antibacterial agents, drugs, tonics, thickeners, ultraviolet absorbents, antioxidants, preservatives, perfumes, 15 and pigments. "Preparation of this emulsified composition" This emulsified composition can be prepared with a conventional preparation method for emulsified compositions; specifically, the emulsifier-in-water method, the emulsifier-in-oi1 method, and the alternate addition method. As mentioned above, this emulsified composition is an oil-in-water emulsified composition; as long as it is so it can be cream or emulsion, but it is suitable for use in products primarily or secondarily aiming at removing dirt. The most preferable applications for the present invention are cleansing creams for removing cosmetics and facial massage creams. The composition can become a cushion between the hand and skin during cosmetic removal and massage to alleviate the skin strain due to stimulation such as frict ion. The main optional ingredients in this emulsified composition that can be in these forms, in addition to the aforementioned essential 16 ingredients, include, as the water phase ingredients for example, one, two, or more humectants such as glycerin, propylene glycol, dipropylene glycol, 1,3-butylene glycol, low molecular weight polyethylene glycol, sorbitol, maltitol, pyrrolidonecarboxylic soda, hyaluronic acid, and chondroitin sulfate in the amount of 5.0-50 wt%, preferably 10-35 wt%, of the total amount of the water phase; thickeners such as bentonite, carboxyvinyl polymer, hydroxypropy1 cellulose, POP, and POE thickeners in the amount of 0.2-2.0 wt%, preferably 0.5-1.5 wt%, of the total amount of the water phase; water soluble preservatives such as methylparaben, hibitane glycolate, and phenoxyethanol; as well as water soluble drugs, crude drugs, germicides, sequestering agents, dyes, and pigment powders; these can be added to this emulsified composition as necessary. EXAMPLES The present invention is described below by referring to Examples, but this is not to limit the scope of the present invention. The blend 17 ratios are in wt% units. 'Test examples' 1. Formulations of test samples In order to verify the effect of the present invention, formulations of the oil-in-water creams shown in Table 1 were prepared and "stability", "richness at initial spread", and "stickiness after being wiped off" were evaluated based on the criteria described in the following 2. The results are also described in Table 1. The oil-in-water cream of each sample shown in Table 1 was prepared by thoroughly dissolving the oil phase (oil ingredients, fatty acids, nonionic surfactants, and perfumes) and the water phase (other than the oil phase) separately at 70°C, adding the oil phase to the water phase, emulsifying the mixture by using an emulsifier, and then cooling the emulsion with a heat exchanger down to 35°C and putting it in a container. 2. Evaluation criteria (1) Stability 18 Each test sample was left alone for one month at 0°C, 50°C, and room temperature, and external appearance, state, color, odor, etc. the sample was investigated; comprehensive evaluation was made based on the following criteria. 0: No change from the initial state. A : Some coalescing of the emulsified particl observed but there seems to be no problem in of stability. X: Stability is very poor and separation is observed particularly at 50°C. (2) Richness at the time of application/massage 2.5 g was put on a hand and spread on the face, and sensory evaluation was conducted; evaluation was done by comparison with the basic formulation (in Table 1, the evaluation column for the basic formulation is entered as *-*.) 0'. Richness is felt abundantly. 0A : More richness is felt compared with the basic formulat i on. A '• Richness equivalent of that of the basic formulation is felt. X: Richness is not felt and the initial spread is 19 light. (3) Stickiness after being wiped off After letting an appropriate amount be absorbed on the face, the sample was wiped off with tissue paper and the residual sensation was evaluated. 0: No stickiness remains and adequately moist tactile sensation remains. A : Some stickiness remains. X: Stickiness remains to the point where one wants to rub with tissue paper several times. 20 {Table 1} *AA: Appropriate amount Stearic acid exists as sodium stearate due to 21 saponifi cation. Polyethylene glycol 1000-" 950-1050 Polyethylene glycol 4000". 3000-3700 Polyethylene glycol 6000: 6000-7500 Polyethylene glycol 11000 weight 9300-12500 Polyethylene glycol 20000 weight 15500-25000 These results indica the relative amount of th solid or semisolid oil in formulation, as attempted 1 and 2, would result in stickiness after being wi stability. When polyethy molecular weight 950-1050 weight and liquid at room richness was not felt if or less and the stability ratio was 5.0% or more (C Average molecular weight Average molecular weight Average molecular weight Average molecular Average molecular te that the increase in e oil phase or in the gredi ents in the in Comparative examples problems such as ped off and decreased lene glycol 1000 (average ), which is low molecular temperature, is used, the blend ratio was 3.0% worsened if the blend omparative examples 3 and 22 4). When polyethylene glycol 4000 (average molecular weight 3000-3700), which is high molecular weight and solid at room temperature, was used, sufficient richness was felt if the blend ratio was 3.0% (Example 1). When it was over 4.0%, the emulsification became unstable (Comparative example 5). Similarly, polyethylene glycol 6000 (average molecular weight 6000-7500), 11000 (average molecular weight 9300-12500), and 20000 (average molecular weight 15500-25000) were used for evaluation and the aforementioned results were obtained (Examples 2-4). Formulation examples of the present invention are disclosed below. In the following formulation examples, the fatty acids and alkali agents are saponified and thus exist in the final products as fatty acid soaps. 'Formulation example 1* Cleansing cream Ingredients Blend ratio (wt%) (A) Mineral oil 41.0 23 9. 0 4. 0 1. 0 1. 0 2. 0 0. 5 1. 2 0. 9 0. 5 Appropriate amount Olefin ol igomer Petrolatum Microcrystal1ine wax Beheni c acid Stearyl alcohol Squalane PEG (30) stearate POE (10) hydrogenated castor oil Monoglyceride stearate Perfume 5. 5 0. 1 Appropriate amount 0. 04 3. 0 Appropriate amount Balance (B) 1,3-butylene glycol Potassium hydroxide Preservat ive Xanthan gum Polyethylene glycol 4000 Chelating agent Ion-exchanged water Preparation method> Oil phase A and water phase B are thoroughly dissolved at 70°C and A is added to B, followed by emulsification with an emulsifier. The emulsified product is cooled down to the final temperature of 35°C by using a heat exchanger and then put into a container. Formulation example 2" Cleansing cream PEG (40) hydrogenated castor oil isostearate 1. 8 Glyceryl monostearate PEG (5) glyceryl stearate Perfume Ingredi ent s (A) Olefin oligomer Beeswax Petrolatum Triethylhexanoin Stearic acid Steary1 alcohol Squalane (B) Propylene glycol Glycerin Potassium hydroxide Preservat ive Xanthan gum Polyethylene glycol 6000 Chelating agent Ion-exchanged water Blend ratio (wt%) 35. 0 3. 0 10. 0 2. 0 1. 0 2. 0 5. 0 0. 2 0. 7 Appropriate amount 2. 0 3. 0 0. 1 Appropriate amount 0. 01 2. 5 Appropriate amount Balance Preparation method> Based on Formulation example 1 Formulation example 3" Cleansing cream Blend ratio (wt%) Ingredi ents 40. 5 9. 0 7. 0 2. 0 1. 3 1. 0 1. 0 0. 5 1. 5 1. 1 Appropriate amount (A) Mineral oil Cetyl ethylhexanoate Petrolatum Dimethicone polyol Stearic acid Steary1 alcohol Batyl alcohol Squalane POE (30) hydrogenated castor oil PEG (5) glyceryl stearate Perfume 5. 0 3. 0 0. 1 Appropriate amount 0. 04 1. 5 Appropriate amount (B) 1,3-butylene glycol Glycerin Sodium hydroxide Preservat ive Carbomer Polyethylene glycol 11000 Chelating agent Ion-exchanged water Preparation method> Based on Formulation example 1. Balance Formulation example 4" Cleansing cream Ingredients (A) Mineral oil Cetyl ethylhexanoate Petrolatum Tri ethylhexanoin Stearic acid Stearyl alcohol Beheny1 alcohol Squalane P0E(60) hydrogenated castor oil Sorbitan stearate Perfume (B) Dipropylene glycol Potassium hydroxide Preservat ive Carbomer Polyethylene glycol 20000 Chelating agent Blend ratio (wt%) 20. 0 9. 0 5. 0 2. 0 1. 0 1. 0 1. 0 20. 0 1. 2 1. 2 Appropriate amount 5. 0 0. 1 Appropriate amount 0. 04 1. 0 27 Ion-exchanged water Preparation method) Based on Formulation example 1. Balance 'Formulation example 5" Massage cream Ingredients Blend ratio (wt%) 25. 0 5. 0 5. 0 3. 0 1. 5 0. 5 2. 0 1. 3 2. 8 0. 5 Appropriate amount (A) Squalane Pentaerythritol tetra-2-ethylhexanoate Hydrogenated palm oil Microcrystal1ine wax Steary1 alcohol Behenyl alcohol Stearic acid Monoglyceride stearate PEG (5) glyceryl stearate POE(20) sorbitan monostearate Perfume (B) Glycerin 4.0 Isopropylene glycol 2.0 Polyethylene glycol 400 3.0 Polyethylene glycol 20000 1.1 Sodium hydroxide 0.03 Potassium hydroxide 0.07 28 0. 03 Appropriate amount Appropriate amount Balance Carbomer Chelating agent Preservat ive Ion-exchanged water Preparation method> Based on Formulation example 1 "Formulation example 6* Massage cream Ingredients Blend ratio (wt%) (A) Mineral oil 28.0 Petrolatum 5.0 Solid paraffin 4.0 Cety1 al cohol 1.5 Stearyl alcohol 1.5 Steari c acid 0.8 Palmitic acid 1.2 Self-emulsified monoglyceride stearate 2.0 POE(40) hydrogenated castor oil 2.5 Perfume (B) Propylene glycol Sorbit solution Triethanolamine Carbomer Appropriate amount 5. 0 5. 0 2. 2 0. 04 29 0. 01 1. 7 Appropriate amount Appropriate amount Balance Xanthan gum Polyethylene glycol 6000 Pres ervat ive Chelating agent Ion-exchanged water Preparation method) Based on Formulation example 1 INDUSTRIAL APPLICABILITY The oil-in-water emulsified composition of the present invention can be used for external preparations. It is particularly suitable to be used for cleansing creams or massage creams. 30 WE CLAIM : 1. An oil-in-water emulsified composition comprising (1) fatty acid soap, the following ingredients (2)-(5) and (6) water: (2) Polyethylene glycol having an average molecular weight of 2000-25000 in the amount of 0.3-4.0 wt% of the composition, (3) one, two, or more of nonionic surfactants having a HLB of 10-17 in the amount of 0.1-5.0 wt% of the composition, (4) one, two, or more of nonionic surfactants having a HLB of 2-10 in the amount of 0.1-5.0 wt% of the composition, and (5) an oil ingredient comprising a solid or semisolid oil ingredient in the amount of 40-70 wt% of the composition. 2. The oil-in-water emulsified composition of claim 1 wherein the solid or semisolid oil ingredient content in said emulsified composition is 5.0-50 wt% of the total amount of the oil ingredient. 3. The oil-in-water emulsified composition of claim 1 or 2 wherein said emulsified composition 31 is a cleansing cream or massage cream. Dated this 28th day of July, 2009 FOR SHISEIDO COMPANY, LTD. By their Agent (Uma Bhattad) KRISHNA & SAURASTRI 32

Documents:

1415-mumnp-2009-abstract.doc

1415-mumnp-2009-abstract.pdf

1415-mumnp-2009-claims.doc

1415-mumnp-2009-claims.pdf

1415-MUMNP-2009-CORRESPONDENCE(15-12-2010).pdf

1415-MUMNP-2009-CORRESPONDENCE(15-4-2011).pdf

1415-MUMNP-2009-CORRESPONDENCE(IPO)-(7-1-2010).pdf

1415-MUMNP-2009-CORRESPONDENCE-(18-11-2009).pdf

1415-mumnp-2009-correspondence.pdf

1415-mumnp-2009-description(complete).doc

1415-mumnp-2009-description(complete).pdf

1415-mumnp-2009-form 1.pdf

1415-MUMNP-2009-FORM 18(15-12-2010).pdf

1415-mumnp-2009-form 2(title page).pdf

1415-mumnp-2009-form 2.doc

1415-mumnp-2009-form 2.pdf

1415-MUMNP-2009-FORM 3(15-4-2011).pdf

1415-MUMNP-2009-FORM 3(18-11-2009).pdf

1415-mumnp-2009-form 3.pdf

1415-mumnp-2009-form 5.pdf

1415-MUMNP-2009-FORM-PCT-IB-338 (18-11-2009).pdf

1415-MUMNP-2009-FORM-PCT-ISA-237(18-11-2009).pdf

1415-mumnp-2009-international publication report a1.pdf

1415-mumnp-2009-other document.pdf

1415-mumnp-2009-pct-ib-304.pdf

1415-mumnp-2009-pct-ib-311.pdf

1415-mumnp-2009-pct-isa-210.pdf

1415-MUMNP-2009-POWER OF ATTORNEY(4-8-2009).pdf