| Title of Invention | "A SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUND” |
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| Abstract | Disclosed is a compound having an excellent DGAT inhibiting activity and an excellent anorexigenic activity or a pharmacologically acceptable salt thereof. Specifically disclosed is a compound represented by general formula (I) or a pharmacologically acceptable salt thereof [in the formula, R1 represents a phenylaminocarbonyl group which may be substituted by 1 to 5 substituents independently selected from the members of the substituent group (A), a benzoxazol-2-yl group which may be substituted by 1 to 3 substituents independently selected from the members of the substituent group (A), or the like; R2's independently represent a C1-C6 alkyl group; R3 represents a group represented by formula -C(=O)-O-R4, or the like; R4 represents a hydrogen atom, a C1-C6 alkyl group which may be substituted by 1 to 3 substituents independently selected from the members of the substituent group (B), or the like; X represents an oxygen atom, a methylene group, a group represented by formula -NH-, or the like; L represents a single bond, a methylene group, or the like; a mark ' ' represents a single bond or a double bond; m represents a number of 1 or 2; n represents an integer of 0 to 5; the substituent group (A) includes a halogen atom, a C1-C6 alkyl group, a C1-C6 halogenated alkyl group, a C1-C6 alkoxy group, and others; the substituent group (B) includes a C3-C6 cycloalkyl group, a phenyl group, a carboxyl group, and others.] (I) |
| Full Text | PLEASE SEE THE SPECIFICATION ATTACHED. |
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1857-MUMNP-2010-ABSTRACT(7-2-2013).pdf
1857-MUMNP-2010-CANCELLED PAGES(7-2-2013).pdf
1857-MUMNP-2010-CLAIMS(AMENDED)-(7-2-2013).pdf
1857-MUMNP-2010-CLAIMS(MARKED COPY)-(7-2-2013).pdf
1857-MUMNP-2010-CORRESPONDENCE(17-8-2012).pdf
1857-MUMNP-2010-CORRESPONDENCE(17-9-2010).pdf
1857-MUMNP-2010-CORRESPONDENCE(2-3-2012).pdf
1857-MUMNP-2010-CORRESPONDENCE(23-2-2011).pdf
1857-MUMNP-2010-CORRESPONDENCE(27-8-2013).pdf
1857-MUMNP-2010-CORRESPONDENCE(28-10-2010).pdf
1857-MUMNP-2010-CORRESPONDENCE(5-9-2011).pdf
1857-MUMNP-2010-CORRESPONDENCE(7-8-2012)-.pdf
1857-MUMNP-2010-CORRESPONDENCE(7-8-2012).pdf
1857-MUMNP-2010-CORRESPONDENCE(9-11-2011).pdf
1857-MUMNP-2010-CORRESPONDENCE(9-9-2010).pdf
1857-MUMNP-2010-ENGLISH TRANSLATION(28-10-2010).pdf
1857-MUMNP-2010-ENGLISH TRANSLATION(9-11-2011).pdf
1857-MUMNP-2010-FORM 1(17-9-2010).pdf
1857-MUMNP-2010-FORM 1(7-2-2013).pdf
1857-MUMNP-2010-FORM 1(7-8-2012).pdf
1857-MUMNP-2010-FORM 13(7-8-2012).pdf
1857-mumnp-2010-form 13(9-9-2010).pdf
1857-MUMNP-2010-FORM 18(9-9-2010).pdf
1857-MUMNP-2010-FORM 2(TITLE PAGE)-(7-2-2013).pdf
1857-MUMNP-2010-FORM 3(17-8-2012).pdf
1857-MUMNP-2010-FORM 3(2-3-2012).pdf
1857-MUMNP-2010-FORM 3(23-2-2011).pdf
1857-MUMNP-2010-FORM 3(27-8-2013).pdf
1857-MUMNP-2010-FORM 3(5-9-2011).pdf
1857-MUMNP-2010-FORM 3(7-2-2013).pdf
1857-MUMNP-2010-FORM PCT-IB-373(7-2-2013).pdf
1857-MUMNP-2010-FORM PCT-ISA-237(7-2-2013).pdf
1857-MUMNP-2010-PETITION UNDER RULE 137(7-2-2013).pdf
1857-MUMNP-2010-REPLY TO EXAMINATION REPORT(7-2-2013).pdf
1857-MUMNP-2010-SPECIFICATION(AMENDED)-(9-9-2010).pdf
| Patent Number | 263469 | ||||||||||||
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| Indian Patent Application Number | 1857/MUMNP/2010 | ||||||||||||
| PG Journal Number | 44/2014 | ||||||||||||
| Publication Date | 31-Oct-2014 | ||||||||||||
| Grant Date | 30-Oct-2014 | ||||||||||||
| Date of Filing | 01-Sep-2010 | ||||||||||||
| Name of Patentee | Daiichi Sankyo Company, Limited | ||||||||||||
| Applicant Address | 3-5-1 Nihonbashi Honcho Chuo-ku Tokyo 103-8426 Japan. | ||||||||||||
Inventors:
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| PCT International Classification Number | C07D217/06,A61K31/472,A61K31/4725 | ||||||||||||
| PCT International Application Number | PCT/JP2009/055738 | ||||||||||||
| PCT International Filing date | 2009-03-24 | ||||||||||||
PCT Conventions:
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