| Title of Invention | "A NOVEL SMALL INTERFERING RNA (SIRNA) DIRECTED AGAINST MELAL BINDING REGION IN THE P2 PROMOTER OF PROTO-ON COGENE C-MYC RESULTING IN ITS TRANSCRIPTIONAL GENE SILENCING" |
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| Abstract | This invention relates to siRNA/ssDNA/dsDNA/ssRNA/dsRNA sequence or any other homologous sequence (upto 80% homology) part of which is homologous to the MElal binding site in the promoter region of c-myc , Where the siRNA sequence is 5" GAACGGAGGGAGGGAUCGCGCUUU 3" 3"UUCUUGCCUCCCUCCCUAGCGCGA 5" and target sequence of the siRNA/ssDNA/dsDNA/ssRNA/dsRNA or any other homologous sequence (upto 80% homology) in the promoter region of c-myc or overlapping any of the CpG islands (underlined) in the above sequence for siRNA/ssDNA/dsDNA/ssRNA/dsRNA/small or large molecule mediated suppression of gene expression, Wherein the target sequence in c-mvc promoter is 5* GAACGGAGGGAGGGATCGCGCT 3" 3" CTTGCCTCCCTCCCTAGCGCGA 5". |
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2746-DEL-2008-Abstract (25-11-2009).pdf
2746-del-2008-Abstract-(09-05-2014).pdf
2746-del-2008-Abstract-(18-11-2009).pdf
2746-DEL-2008-Claims (25-11-2009).pdf
2746-del-2008-Claims-(09-05-2014).pdf
2746-del-2008-Claims-(09-10-2014).pdf
2746-del-2008-Claims-(18-11-2009).pdf
2746-del-2008-Correspondence Others-(09-05-2014).pdf
2746-del-2008-Correspondence Others-(09-10-2014).pdf
2746-DEL-2008-Correspondence-Others (25-11-2009).pdf
2746-DEL-2008-Correspondence-Others-(08-12-2009).pdf
2746-del-2008-Correspondence-Others-(18-11-2009).pdf
2746-del-2008-correspondence-others.pdf
2746-DEL-2008-Correspondence-PO-(08-12-2009).pdf
2746-DEL-2008-Description (Complete) (25-11-2009).pdf
2746-del-2008-Description (Complete)-(18-11-2009).pdf
2746-del-2008-description (provisional).pdf
2746-del-2008-Drawings-(18-11-2009).pdf
2746-DEL-2008-Form-18-(08-12-2009).pdf
2746-del-2008-Form-2-(18-11-2009).pdf
2746-del-2008-Form-3-(09-05-2014).pdf
2746-DEL-2008-Form-5 (25-11-2009).pdf
2746-del-2008-Form-5-(18-11-2009).pdf
| Patent Number | 263597 | ||||||||||||
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| Indian Patent Application Number | 2746/DEL/2008 | ||||||||||||
| PG Journal Number | 46/2014 | ||||||||||||
| Publication Date | 14-Nov-2014 | ||||||||||||
| Grant Date | 05-Nov-2014 | ||||||||||||
| Date of Filing | 04-Dec-2008 | ||||||||||||
| Name of Patentee | DEPARTMENT OF BIOTECHNOLOGY | ||||||||||||
| Applicant Address | BLOCK-2, 7TH FLOOR, CGO COMPLEX, LODHI ROAD, NEW DELHI-110 003 | ||||||||||||
Inventors:
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| PCT International Classification Number | C12N 15/00 | ||||||||||||
| PCT International Application Number | N/A | ||||||||||||
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