Title of Invention | ARYLALKYLCARBAMATE DERIVATIVES AND PROCESSES FOR PREPARATION THEREOF |
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Abstract | The invention relates to a compound having general formula (I), wherein: n represents an integer of between 1 and 6; A is selected from one or more X, Y and/or Z groups; X represents an optionally-substituted C1-2-alkylene group; Y represents an optionally-substituted C2-alkenylene group or a -C<u>=</u>C- group; Z represents a C3-7-cycloalkyl group having formula (II) in which m represents an integer of between 1 and 5, and p and q represent integers and are defined such that p+q equals a number of between 1 and 5; R1 represents a hydrogen atom, a halogen atom or a hydroxyl, cyano, nitro, C1-3-alkyl, C1-3-alkoxy, C1-3-thioalkyl, C1-3-fluoroalkyl, C1-3-fluoroalkoxy, C1-3-fluorothioalkyl group; R2 represents a hydrogen atom, a halogen atom or a cyano, nitro, hydroxyl, C1-3-alkyl, C1-3-alkoxy, C1-3-thioalkyl, C1-3-fluoroalkyl, C1-3-fluoroalkoxy, C1-3-fluorothioalkyl group, or an optionally-substituted aromatic or heteroaromatic group; R3 represents either a 2,2,2-trifluoroethyl group or an optionally-substituted phenyl group; and R6 and R7 represent independently of each other a C1-3-alkyl group, a phenyl; said compound taking the form of a base, an acid addition salt, a hydrate or a solvate. The invention also relates to the use of the compound in therapeutics. |
Full Text | The invention relates to arylalkylcarbamate derivatives, to the preparation thereof and to the use thereof in therapeutics. The compounds of the invention correspond to general formula (I): in which n represents an integer between 1 and 6; A is chosen from one or more groups X, Y and/or Z; X represents a C1-2-alkylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; Y represents a C2-alkenylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; or a group -C≡C- Z represents a C3-7-cycloalkyl group of formula: m represents an integer ranging from 1 to 5; p and q represent integers and are defined such that p+q is a number ranging from 1 to 5; R1 represents a hydrogen atom, a halogen atom, or a hydroxyl, cyano, nitro, C1-3-alkyl, C1-3-alkoxy, C1-3- thioalkyl, C1-3-f luoroalkyl, C1-3-f luoroalkoxy or C1-3- fluorothioalkyl group; R2 represents a hydrogen atom, a halogen atom, or a cyano, nitro, hydroxyl, C1-3-alkyl, C1-3-alkoxy, C1-3-thioalkyl, C1-3-fluoroalkyl, C1-3-f luoroalkoxy or C1-3-fluorothioalkyl group; or a group chosen from a phenyl, naphthalenyl, biphenyl, phenylethylenyl, naphthylethylenyl, pyridinyl, pyrimidinyl, pyrazinyl, pyridazinyl, triazinyl, indanyl, indenyl, quinolinyl, isoquinolinyl, quinazolinyl, quinoxalinyl, phthalazinyl, cinnolinyl, thienyl, furyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, thiadiazolyl, oxadiazolyl, triazolyl, benzothienyl, benzofuryl, dibenzofuryl, benzimidazolyl, benzo- triazolyl, indolyl, isoindolyl, indazolyl, benzoxazolyl, benzisoxazolyl, benzothiazolyl, benziso- thiazolyl, dihydroindolyl, pyrrolopyridinyl, furo- pyridinyl, thienopyridinyl, imidazopyridinyl, oxazolopyridinyl, thiazolopyridinyl, pyrazolopyridinyl, isoxazolopyridinyl, isothiazolopyridinyl, tetrahydro- quinolinyl, tetrahydroisoquinolinyl, phenyloxy, phenylthio, phenylsulfonyl, benzoyl, phenylmethoxy, phenylethoxy, phenylpropoxy, naphthalenyloxy, naphthalenylmethoxy, naphthalenylethoxy, naphthalenyl- propoxy, quinolinoxy and isoquinolinoxy, and optionally substituted with one or more substituents chosen from a halogen atom, and the following groups: hydroxyl, cyano, nitro, C1-4-alkyl, C1-4-alkoxy, C1-4-thioalkyl, C1-3-fluoroalkyl, C1-3-f luoroalkoxy, C1-3- fluorothioalkyl, phenyloxy, benzyloxy, piperidyl, pyrrolidinyl, morpholinyl, NH2, NHR6, NR6R7, NHCOR6, COR6, CO2RS, SO2R6, -O- (C1-3-alkylene) -O-, 4-piperazinyl optionally substituted with a C1-3-alkyl or with a benzyl; R3 represents either a 2,2,2-trifluoroethyl group, or a phenyl group optionally substituted with one or more halogen atoms or cyano, nitro, C1-3-alkyl, C1-3- alkoxy, trifluoromethyl or trifluoromethoxy groups, and R6 and R7 represent, independently of one another, a C1-3-alkyl group or a phenyl. . In the context of the invention, the compounds of general formula (I) can therefore comprise several groups A which may be identical to or different from one another. The following compounds are not part of the invention: - 2,2,2-trifluoroethyl benzylcarbamate; - 2,2,2-trifluoroethyl 4-methoxybenzylcarbamate; - 4-nitrophenyl 2-[4-(phenylmethoxy)phenyl]ethyl- carbamate; - 4-chloro-2-nitrophenyl 2-(4-(chlorophenyl)ethyl- carbamate; - 4-nitrophenyl 2- (3,4-dimethoxyphenyl)ethylcarbamate; - phenyl 2-(3,4-dimethoxyphenyl)ethylcarbamate; - 4-cyanophenyl 2-(4-methylphenyl)ethylcarbamate; - 2,4,5-trichlorophenyl 2-(4-chlorophenyl)ethyl- carbamate; - phenyl 4-chlorobenzylcarbamate; - phenyl 4-methoxybenzylcarbamate; - 4-fluorophenyl 2-(4-methoxyphenyl)ethylcarbamate; - phenyl 3-nitrobenzylcarbamate; - 4-cyanophenyl 4-methoxybenzylcarbamate; - phenyl 3-chlorobenzylcarbamate,• - phenyl 3,4-dichlorobenzylcarbamate; - 4-nitrophenyl 2-(4-hydroxyphenyl)ethylcarbamate; - phenyl 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo- [4,5-b]pyridin-3-yl)phenyl]ethylcarbamate; - phenyl 2-[4-(3-thienyl)phenyl]propylcarbamate; - phenyl 2-[4-(2-amino-4-thiazolyl)phenyl]ethyl- carbamate; - 2,3,4,5,6-pentafluorophenyl 4-bromobenzylcarbamate. Among the compounds of general formula (I) , a first subgroup of compounds consists of the compounds for which: n represents an integer between 1 and 6; A is chosen from one or more groups X, Y and/or Z; X represents a C1-2-alkylene group optionally- substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; Y represents a C2-alkenylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; or a group -C≡C-; Z represents a C3-7-cycloalkyl group of formula: m represents an integer ranging from 1 to 5; p and q represent integers and are defined such that p+q is a number ranging from 1 to 5; R1 represents a hydrogen atom, a halogen atom, or a hydroxyl, cyano, nitro, C1-3-alkyl, C1-3-alkoxy, C1-3- thioalkyl, C1-3-f luoroalkyl, C1-3-f luoroalkoxy or C1-3- fluorothioalkyl group; R2 represents a halogen atom, or a nitro, hydroxyl, C1-3-alkyl or C1-3- alkoxy group; and R3 represents either a 2,2,2-trifluoroethyl group, or a phenyl group optionally substituted with one or more halogen atoms, or cyano, nitro, C1-3-alkyl, C1-3- alkoxy, trifluoromethyl or trifluoromethoxy groups. The following compounds are not part of the first subgroup of compounds above: - 2,2,2-trifluoroethyl 4-methoxybenzylcarbamate; - 4-chloro-2-nitrophenyl 2-(4-chlorophenyl)ethyl- carbamate; - 4-nitrophenyl 2-(3,4-dimethoxyphenyl)ethylcarbamate; - phenyl 2-(3,4-dimethoxyphenyl)ethylcarbamate; - 4-cyanophenyl 2-(4-methylphenyl)ethylcarbamate; - 2,4,5-trichlorophenyl 2-(4-chlorophenyl)ethyl- carbamate; - phenyl 4-chloropbenzylcarbamate; - phenyl 4-methoxybenzylcarbamate; - 4-fluorophenyl 2-(4-methoxyphenyl)ethylcarbamate; - phenyl 3-nitrobenzylcarbamate; - 4-cyanophenyl 4-methoxybenzylcarbamate; - phenyl 3-chlorobenzylcarbamate; - phenyl 3,4-dichlorobenzylcarbamate; - 4-nitrophenyl 2-(4-hydroxyphenyl)ethylcarbamate; - 2,3,4,5,6-pentafluorophenyl 4-bromobenzylcarbamate. Among the compounds of the general formula (I) , a second subgroup of compounds consists of the compounds for which: n represents an integer between 1 and 6; A is chosen from one or more groups X, Y and/or Z; X represents a C1-2-alkylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-s-alkylene groups; Y represents a C2-alkenylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; or a group -C≡C-; Z represents a C3-7-cycloalkyl group of formula: m represents an integer ranging from 1 to 5; p and q represent integers and are defined such that p+q is a number ranging from 1 to 5; R1 represents a hydrogen atom, a halogen atom, or a hydroxyl, cyano, nitro, C1-3-alkyl, C1-3-alkoxy, C1-3- thioalkyl, C1-3-f luoroalkyl, C1-3-f luoroalkoxy or C1-3- fluorothioalkyl group; R2 represents a hydrogen atom, or a cyano, C1-3-thioalkyl, C1-3- fluoroalkyl, C1-3-fluoroalkoxy or C1-3-f luorothioalkyl group, or a group chosen from a phenyl, naphthalenyl, biphenyl, phenylethylenyl, naphthylethylenyl, pyridinyl, pyrimidinyl, pyrazinyl, pyridazinyl, triazinyl, indanyl, indenyl, guinolinyl, isoquinolinyl, quinazolinyl, quinoxalinyl, phthalazinyl, cinnolinyl, thienyl, furyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, thiadiazolyl, oxadiazolyl, triazolyl, benzothienyl, benzofuryl, dibenzofuryl, benzimidazolyl, benzo- triazolyl, indolyl, isoindolyl, indazolyl, benzoxazolyl, benzisoxazolyl, benzothiazolyl, benziso- thiazolyl, dihydroindolyl, pyrrolopyridinyl, furo- pyridinyl, thienopyridinyl, imidazopyridinyl, oxazolopyridinyl, thiazolopyridinyl, pyrazolopyridinyl, isoxazolopyridinyl, isothiazolopyridinyl, tetrahydro- quinolinyl, tetrahydroisoquinolinyl, phenyloxy, phenylthio, phenylsulfonyl, benzoyl, phenylmethoxy, phenylethoxy, phenylpropoxy, naphthalenyloxy, naphthalenylmethoxy, naphthalenylethoxy, naphthalenyl- propoxy, quinolinoxy and isoquinolinoxy, and optionally substituted with one or more substituents chosen from a halogen atom, and the following groups: hydroxyl, cyano, nitro, C1-4-alkyl, C1-4-alkoxy, C1-4-thioalkyl, C1-3-fluoroalkyl, C1-3-f luoroalkoxy, C1-3-f luorothioalkyl, phenyloxy, benzyloxy, piperidyl, pyrrolidinyl, morpholinyl, NH2, NHRe, NR6R7, NHCOR6, COR5, C02R6, SO2R6, -O-(C1-3-alkylene)-O-, 4-piperazinyl optionally substituted with a C1-3-alkyl or with a benzyl; R3 represents either a 2,2,2-trifluoroethyl group, or a phenyl group optionally substituted with one or more halogen atoms or cyano, nitro, C1-3-alkyl, C1-3- alkoxy, trifluoromethyl or trifluoromethoxy groups, and R6 and R7 represent, independently of one another, a C1-3-alkyl group or a phenyl. The following compounds are not part of the second subgroup of compounds above: - 2,2,2-trifluoroethyl benzylcarbamate; - 4-nitrophenyl 2-[4-(phenylmethoxy)phenyl]ethyl- carbamate; - phenyl 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]- pyridin-3-yl)phenyl]ethylcarbamate; - phenyl 2-[4-(3-thienyl)phenyl]propylcarbamate; - phenyl 2- [4-(2-amino-4-thiazolyl)phenyl]ethyl- carbamate . Among the compounds of general formula (I) , a first family of compounds consists of the compounds for which: n represents an integer between 1 and 6; A is chosen from one or more groups X, Y and/or Z; X represents a C1-2-alkylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; Y represents a C2-alkenylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; or a group -C≡C-; Z represents a C3-7-cycloalkyl group of formula: m represents an integer ranging from 1 to 5; p and q represent integers and are defined such that p+q is a number ranging from 1 to 5; R1 represents a hydrogen atom, a halogen atom, or a hydroxyl, cyano, nitro, C1-3-alkyl, C1-3-alkoxy, C1-3- thioalkyl, C1-3-fluoroalkyl, C1-3-fluoroalkoxy or C1-3- fluorothioalkyl group; R2 represents a hydrogen atom, a halogen atom, or a cyano, nitro, hydroxyl, C1-3-alkyl, C1-3-alkoxy, C1-3-thioalkyl, C1-3-fluoroalkyl, C1-3-f luoroalkoxy or C1-3-fluorothioalkyl group, or a group chosen from a phenyl, naphthalenyl, biphenyl, phenylethylenyl, naphthylethylenyl, pyridinyl, pyrimidinyl, pyrazinyl, pyridazinyl, triazinyl, indanyl, indenyl, quinolinyl, isoquinolinyl, quinazolinyl, quinoxalinyl, phthalazinyl, cinnolinyl, thienyl, furyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, thiadiazolyl, oxadiazolyl, triazolyl, benzothienyl, benzofuryl, dibenzofuryl, benzimidazolyl, benzo- triazolyl, indolyl, isoindolyl, indazolyl, benzoxazolyl, benzisoxazolyl, benzothiazolyl, benziso- thiazolyl, dihydroindolyl, pyrrolopyridinyl, furo- pyridinyl, thienopyridinyl, imidazopyridinyl, oxazolopyridinyl, thiazolopyridinyl, pyrazolopyridinyl, isoxazolopyridinyl, isothiazolopyridinyl, tetrahydro- quinolinyl, tetrahydroisoquinolinyl, phenyloxy, phenylthio, phenylsulfonyl, benzoyl, phenylmethoxy, phenylethoxy, phenylpropoxy, naphthalenyloxy, naphthalenylmethoxy, naphthalenylethoxy, naphthalenyl- propoxy, quinolinoxy and isoquinolinoxy, and optionally substituted with one or more substituents chosen from a halogen atom, and the following groups: hydroxyl, cyano, nitro, C1-4-alkyl, C1-4-alkoxy, C1-4-thioalkyl, C1-3-fluoroalkyl, C1-3-f luoroalkoxy, C1-3-f luorothioalkyl, phenyloxy, benzyloxy, piperidyl, pyrrolidinyl, morpholinyl, NH2, NHR6, NR6R7, NHCOR6, COR6, CO2R6, SO2R6, -O-(Ca-3-alkylene)-O-, 4-piperazinyl optionally substituted with a C1-3-alkyl or with a benzyl; R3 represents either a 2,2,2-trifluoroethyl group, or a phenyl group optionally substituted with one or more halogen atoms or cyano, nitro, C1-3-alkyl, C1-3- alkoxy, trifluoromethyl or trifluoromethoxy groups, and R6 and R7 represent, independently of one another, a C1-3-alkyl group or a phenyl; on the condition that when R3 represents a phenyl group, if A represents a propylene, then R2 does not represent a thienyl. The following compounds are not part of the first family of compounds defined above: - 2,2,2-trifluoroethyl benzylcarbamate; - 2,2,2-trifluoroethyl 4-methoxybenzylcarbamate; - 4-nitrophenyl 2-[4-(phenylmethoxy)phenyl]ethyl- carbamate; - 4-chloro-2-nitrophenyl 2- (4-(chlorophenyl)ethyl- carbamate; - 4-nitrophenyl 2-(3,4-dimethoxyphenyl)ethylcarbamate; - phenyl 2-(3,4-dimethoxyphenyl)ethylcarbamate; - 4-cyanophenyl 2-(4-methylphenyl)ethylcarbamate; - 2,4,5-trichlorophenyl 2-(4-chlorophenyl)ethyl- carbamate; - phenyl 4-chlorobenzylcarbamate; - phenyl 4-methoxybenzylcarbamate; - 4-fluorophenyl 2-(4-methoxyphenyl)ethylcarbamate; - phenyl 3-nitrobenzylcarbamate; - 4-cyanophenyl 4-methoxybenzylcarbamate; - phenyl 3-chlorobenzylcarbamate; - phenyl 3,4-dichlorobenzylcarbamate; - 4-nitrophenyl 2-(4-hydroxyphenyl)ethylcarbamate; - phenyl 2- [4-(2-ethyl-5,7-dimethyl-3H-imidazo- [4,5-b]pyridin-3-yl)phenyl]ethylcarbamate; - phenyl 2-[4-(2-amino-4-thiazolyl)phenyl]ethyl- carbamate; - 2,3,4,5,6-pentafluorophenyl 4-bromobenzylcarbamate. Among the compounds of general formula (I) , a second family of compounds consists of the compounds for which: - when R3 represents a 2,2,2-trifluoroethyl group, then n represents an integer between 1 and 6; A is chosen from one or more groups X, Y and/or Z; X represents a C1-2-alkylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; Y represents a C2-alkenylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; or a group -C≡C-; Z represents a C3-7-cycloalkyl group of formula: m represents an integer ranging from 1 to 5; p and q represent integers and are defined such that p+q is a number ranging from 1 to 5; R1 represents a hydrogen atom, a halogen atom, or a hydroxyl, cyano, nitro, C1-3-alkyl, C1-3-alkoxy, C1-3- thioalkyl, C1-3-f luoroalkyl, C1-3-fluoroalkoxy or C1-3- fluorothioalkyl group; R2 represents a hydrogen atom, a halogen atom, or a cyano, nitro, hydroxyl, C1-3-alkyl, C1-3-alkoxy, C1-3-thioalkyl, C1-3-f luoroalkyl, C1-3-f luoroalkoxy or C1-3-fluorothioalkyl group, or a group chosen from a phenyl, naphthalenyl, biphenyl, phenylethylenyl, naphthylethylenyl, pyridinyl, pyrimidinyl, pyrazinyl, pyridazinyl, triazinyl, indanyl, indenyl, quinolinyl, isoquinolinyl, quinazolinyl, quinoxalinyl, phthalazinyl, cinnolinyl, thienyl, furyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, thiadiazolyl, oxadiazolyl, triazolyl, benzothienyl, benzofuryl, dibenzofuryl, benzimidazolyl, benzo- triazolyl, indolyl, isoindolyl, indazolyl, benzoxazolyl, benzisoxazolyl, benzothiazolyl, benziso- thiazolyl, dihydroindolyl, pyrrolopyridinyl, furo- pyridinyl, thienopyridinyl, imidazopyridinyl, oxazolopyridinyl, thiazolopyridinyl, pyrazolopyridinyl, isoxazolopyridinyl, isothiazolopyridinyl, tetrahydro- quinolinyl, tetrahydroisoquinolinyl, phenyloxy, phenylthio, phenylsulfonyl, benzoyl, phenylmethoxy, phenylethoxy, phenylpropoxy, naphthalenyloxy, naphthalenylmethoxy, naphthalenylethoxy, naphthalenyl- propoxy, quinolinoxy and isoquinolinoxy, and optionally substituted with one or more substituents chosen from a halogen atom, and the following groups: hydroxyl, cyano, nitro, C1-4-alkyl, C1-4-alkoxy, C1-4-thioalkyl, C1-3-fluoroalkyl, C1-3-f luoroalkoxy, C1-3-f luorothioalkyl, phenyloxy, benzyloxy, piperidyl, pyrrolidinyl, morpholinyl, NH2, NHRS, NR6R7, NHCOR6, COR6l CO2R6, SO2R6, -O-(C1-3-alkylene)-O-, 4-piperazinyl optionally substituted with a C1-3-alkyl or with a benzyl; and R6 and R7 represent, independently of one another, a C1-3-alkyl group or a phenyl; - when R3 represents a phenyl group optionally substituted with one or more halogen atoms, or cyano, nitro, C1-3-alkyl, C1-3-alkoxy, trifluoromethyl or trifluoromethoxy groups, then n represents an integer between 1 and 6; A is chosen from one or more groups X, Y and/or Z; X represents a C1-2-alkylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; Y represents a C2-alkenylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; or a group -C≡C-; Z represents a C3-7-cycloalkyl group of formula: m represents an integer ranging from 1 to 5; p and g represent integers and are defined such that p+q is a number ranging from 1 to 5; R1 represents a hydrogen atom, a halogen atom, or a hydroxyl, cyano, nitro, C1-3-alkyl, C1-3-alkoxy, C1-3- thioalkyl, C1-3-f luoroalkyl, C1-3-fluoroalkoxy or C1-3- fluorothioalkyl group; R2 represents a hydrogen atom, a halogen atom, or a cyano, nitro, hydroxyl , C1-3-alkyl, C1-3-alkoxy, C1-3-thioalkyl, C1-3-f luoroalkyl, C1-3-f luoroalkoxy or C1-3-fluorothioalkyl group, or a group chosen from a phenyl, naphthalenyl, biphenyl, phenylethylenyl, naphthylethylenyl, pyridinyl, pyrimidinyl, pyrazinyl, pyridazinyl, triazinyl, indanyl, indenyl, quinolinyl, isoquinolinyl, quinazolinyl, quinoxalinyl, phthalazinyl, cinnolinyl, furyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, thiadiazolyl, oxadiazolyl, triazolyl, benzothienyl, benzofuryl, dibenzofuryl, benzimidazolyl, benzotriazolyl, indolyl, isoindolyl, indazolyl, benzoxazolyl, benzisoxazolyl, benzothiazolyl, benzisothiazolyl, dihydroindolyl, pyrrolopyridinyl, furopyridinyl, thienopyridinyl, imidazopyridinyl, oxazolopyridinyl, thiazolopyridinyl, pyrazolopyridinyl, isoxazolopyridinyl, isothiazolopyridinyl, tetrahydroquinolinyl, tetrahydroisoquinolinyl, phenyloxy, phenylthio, phenylsulfonyl, benzoyl, phenylmethoxy, phenylethoxy, phenylpropoxy, naphthalenyloxy, naphthalenylmethoxy, naphthalenylethoxy, naphthalenylpropoxy, quinolinoxy and isoquinolinoxy, and optionally substituted with one or more substituents chosen from a halogen atom, and the following groups: hydroxyl, cyano, nitro, C1-4- alkyl, C1-4-alkoxy, C1-4-thioalkyl, C1-3-f luoroalkyl, C1-3- fluoroalkoxy, C1-3-fluorothioalkyl, phenyloxy, benzyloxy, piperidyl, pyrrolidinyl, morpholinyl, NH2, NHR6, NReR7, NHCOR6, COR6, CO2R6, S02Rs, -O-(C1-3- alkylene)-O-, 4-piperazinyl optionally substituted with a C1-3-alkyl or with a benzyl; and R6 and R7 represent, independently of one another, a C1-3-alkyl group or a phenyl. The following compounds are not part of the second family of compounds defined above: - 2,2 ,2-trifluoroethyl benzylcarbamate; - 2,2 , 2-trifluoroethyl 4-methoxybenzylcarbamate; - 4-nitrophenyl 2- [4- (phenylmethoxy)phenyl]ethyl- carbamate; - 4-chloro-2-nitrophenyl 2-(4-(chlorophenyl)ethyl- carbamate; - 4-nitrophenyl 2-(3,4-dimethoxyphenyl)ethylcarbamate ; - phenyl 2-(3,4-dimethoxyphenyl)ethylcarbamate; - 4-cyanophenyl 2-(4-methylphenyl)ethylcarbamate; - 2,4, 5-trichlorophenyl 2-(4-chlorophenyl)ethyl- carbamate; - phenyl 4-chlorobenzylcarbamate; - phenyl 4-methoxybenzylcarbamate; - 4-fluorophenyl 2-(4-methoxyphenyl)ethylcarbamate; - phenyl 3-nitrobenzylcarbamate; - 4-cyanophenyl 4-methoxybenzylcarbamate; - phenyl 3-chlorobenzylcarbamate; - phenyl 3,4-dichlorobenzylcarbamate; - 4-nitrophenyl 2-(4-hydroxyphenyl)ethylcarbamate; - phenyl 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo- [4,5-b]pyridin-3-yl)phenyl]ethylcarbamate; - phenyl 2-[4-(2-amino-4-thiazolyl)phenyl]ethyl- carbamate; - 2,3,4,5,6-pentafluorophenyl 4-bromobenzylcarbamate. Among the compounds of general formula (I) , a third family of compounds consists of the compounds for which: n represents an integer between 1 and 6; A is chosen from one or more groups X, Y and/or Z; X represents a C1-2-alkylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; Y represents a C2-alkenylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; or a group -C≡C-; Z represents a C3-7-cycloalkyl group of formula: m represents an integer ranging from 1 to 5; p and q represent integers and are defined such that p+q is a number ranging from 1 to 5; R1 represents a hydrogen atom, a halogen atom, or a hydroxyl, cyano, nitro, C1-3-alkyl, C1-3-alkoxy, C1-3- thioalkyl, C1-3-f luoroalkyl, C1-3-f luoroalkoxy or C1-3- fluorothioalkyl group; R2 represents a hydrogen atom, a halogen atom, or a cyano, nitro, hydroxyl, C1-3-alkyl, C1-3-alkoxy, C1-3-thioalkyl, C1-3-f luoroalkyl, C1-3-f luoroalkoxy or C1-3-fluorothioalkyl group, or a group chosen from a phenyl, naphthalenyl, biphenyl, phenylethylenyl, naphthylethylenyl, pyridinyl, pyrimidinyl, pyrazinyl, pyridazinyl, triazinyl, indanyl, indenyl, quinolinyl, isoquinolinyl, quinazolinyl, quinoxalinyl, phthalazinyl, cinnolinyl, thienyl, furyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, thiadiazolyl, oxadiazolyl, triazolyl, benzothienyl, benzofuryl, dibenzofuryl, benzimidazolyl, benzo- triazolyl, indolyl, isoindolyl, indazolyl, benzoxazolyl, benzisoxazolyl, benzothiazolyl, benziso- thiazolyl, dihydroindolyl, pyrrolopyridinyl, furo- pyridinyl, thienopyridinyl, imidazopyridinyl, oxazolopyridinyl, thiazolopyridinyl, pyrazolopyridinyl, isoxazolopyridinyl, isothiazolopyridinyl, tetrahydro- quinolinyl, tetrahydroisoquinolinyl, phenyloxy, phenylthio, phenylsulfonyl, benzoyl, phenylmethoxy, phenylethoxy, phenylpropoxy, naphthalenyloxy, naphthalenylmethoxy, naphthalenylethoxy, naphthalenyl- propoxy, quinolinoxy and isoquinolinoxy, and optionally substituted with one or more substituents chosen from a halogen atom, and the following groups: hydroxyl, cyano, nitro, C1-4-alkyl, C1-4-alkoxy, C1-4-thioalkyl, C1-3-f luoroalkyl, C1-3-f luoroalkoxy, C1-3-f luorothioalkyl, phenyloxy, benzyloxy, piperidyl, pyrrolidinyl, morpholinyl, NH2, NHR6, NR6R7, NHCOR6, COR6, CO2R6, SO2R6, -O-(C1-3-alkylene)-O-, 4-piperazinyl optionally substituted with a C1-3-alkyl or with a benzyl; R3 represents either a 2,2,2-trifluoroethyl group, or a phenyl group optionally substituted with one or more halogen atoms, or cyano, nitro, C1-3-alkyl, C1-3- alkoxy, trifluoromethyl or trifluoromethoxy groups, and R6 and R7 represent, independently of one another, a C1-3-alkyl group or a phenyl; on the condition that - when R3 represents a 2,2,2-trifluoroethyl group, if A represents a methylene and if Ri represents a hydrogen, then R2 is neither a hydrogen nor a methoxy; if A represents a methylene and if R2 represents a hydrogen, then R1 is neither a hydrogen nor a methoxy; - when R3 represents a phenyl group, if A represents a methylene, then neither R1 nor R2 represents a chlorine atom, a methoxy group or a nitro group; if A represents an ethylene, then neither R1 nor R2 represents a methoxy; R2 represents neither a 2-ethyl-5,7-dimethyl-3H- imidazo[4,5-b]pyridin-3-yl nor a 2-amino-4-thiazolyl; if A represents a propylene, then R2 does not represent a 3-thienyl; - when R3 represents a phenyl group substituted with one to five chlorine or fluorine atoms or nitro or cyano groups, if A represents a methylene, then neither R1 nor R2 represents a methoxy or a bromine atom; if A represents an ethylene, then neither R1 nor R2 represents a chlorine atom, or a hydroxyl, methyl or methoxy group; R2 does not represent a phenylmethoxy. Among the compounds of general formula (I) , a fourth family of compounds consists of the compounds for which: - when R3 represents a 2,2,2-trifluoroethyl group, then n represents an integer between 1 and 6; A is chosen from one or more groups X, Y and/or Z; X represents a C1-2-alkylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; Y represents a C2-alkenylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; or a group -C≡C-; Z represents a C3-7-cycloalkyl group of formula: m represents an integer ranging from 1 to 5; p and q represent integers and are defined such that p+q is a number ranging from 1 to 5; R1 represents a hydrogen atom, a halogen atom, or a hydroxyl, cyano, nitro, C1-3-alkyl, C1-3-alkoxy, C1-3- thioalkyl, C1-3-f luoroalkyl, C1-3-f luoroalkoxy or C1-3- fluorothioalkyl group; R2 represents a halogen atom or a cyano, nitro, hydroxyl, C1-3-alkyl, C2-3-alkoxy, C1-3-thioalkyl, C1-3-f luoroalkyl, C1-3-f luoroalkoxy or C1-3-fluorothioalkyl group, or a group chosen from a phenyl, naphthalenyl, biphenyl, phenylethylenyl, naphthylethylenyl, pyridinyl, pyrimidinyl, pyrazinyl, pyridazinyl, triazinyl, indanyl, indenyl, quinolinyl, isoquinolinyl, quinazolinyl, quinoxalinyl, phthalazinyl, cinnolinyl, thienyl, furyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, thiadiazolyl, oxadiazolyl, triazolyl, benzothienyl, benzofuryl, dibenzofuryl, benzimidazolyl, benzo- triazolyl, indolyl, isoindolyl, indazolyl, benzoxazolyl, benzisoxazolyl, benzothiazolyl, benziso- thiazolyl, dihydroindolyl, pyrrolopyridinyl, furo- pyridinyl, thienopyridinyl, imidazopyridinyl, oxazolopyridinyl, thiazolopyridinyl, pyrazolopyridinyl, isoxazolopyridinyl, isothiazolopyridinyl, tetrahydro- quinolinyl, tetrahydroisoquinolinyl, phenyloxy, phenylthio, phenylsulfonyl, benzoyl, phenylmethoxy, phenylethoxy, phenylpropoxy, naphthalenyloxy, naphthalenylmethoxy, naphthalenylethoxy, naphthalenyl- propoxy, quinolinoxy and isoquinolinoxy, and optionally substituted with one or more substituents chosen from a halogen atom, and the following groups: hydroxyl, cyano, nitro, C1-4-alkyl, C1-4-alkoxy, C1-4-thioalkyl, C1-3-fluoroalkyl, C1-3-f luoroalkoxy, C1-3-f luorothioalkyl, phenyloxy, benzyloxy, piperidyl, pyrrolidinyl, morpholinyl, NH2, NHRS, NR6R7, NHCOR6, COR6, CO2R6, SO2R6, -O-(C1-3-alkylene)-O-, 4-piperazinyl optionally substituted with a C1-3-alkyl or with a benzyl; and R6 and R7 represent, independently of one another, a C1-3-alkyl group or a phenyl; - when R3 represents a phenyl group optionally substituted with one or more halogen atoms, or cyano, nitro, C1-3-alkyl, C1-3-alkoxy, trif luoromethyl or trifluoromethoxy groups, then n represents an integer between 1 and 6; A is chosen from one or more groups X, Y and/or Z; X represents a C1-2-alkylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; Y represents a C2-alkenylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; or a group -C≡C-; Z represents a C3-7-cycloalkyl group of formula: m represents an integer ranging from 1 to 5; p and q represent integers and are defined such that p+q is a number ranging from 1 to 5; R1 represents a hydrogen atom, an iodine atom, or a cyano, C2-3-alkyl, C2-3-alkoxy, C1-3-thioalkyl, C1-3- fluoroalkyl, C1-3-fluoroalkoxy or C1-3-fluorothioalkyl group; R2 represents a hydrogen atom, an iodine atom, or a cyano, C2-3-alkyl, C2-3-alkoxy, C1-3-thioalkyl, C1-3- fluoroalkyl, C1-3-f luoroalkoxy or C1-3f luorothioalkyl group, or a group chosen from a phenyl, naphthalenyl, biphenyl, phenylethylenyl, naphthylethylenyl, pyridinyl, pyrimidinyl, pyrazinyl, pyridazinyl, triazinyl, indanyl, indenyl, quinolinyl, isoquinolinyl, quinazolinyl, quinoxalinyl, phthalazinyl, cinnolinyl, furyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, isoxazolyl, isothiazolyl, thiadiazolyl, oxadiazolyl, triazolyl, benzothienyl, benzofuryl, dibenzofuryl, benzimidazolyl, benzotriazolyl, indolyl, isoindolyl, indazolyl, benzoxazolyl, benzisoxazolyl, benzothiazolyl, benzisothiazolyl, dihydroindolyl, pyrrolopyridinyl, furopyridinyl, thienopyridinyl, oxazolopyridinyl, thiazolopyridinyl, pyrazolopyridinyl, isoxazolopyridinyl, isothiazolopyridinyl, tetrahydro- quinolinyl, tetrahydroisoquinolinyl, phenyloxy, phenylthio, phenylsulfonyl, benzoyl, phenylethoxy, phenylpropoxy, naphthalenyloxy, naphthalenylmethoxy, naphthalenylethoxy, naphthalenylpropoxy, quinolinoxy and isoquinolinoxy, and optionally substituted with one or more substituents chosen from a halogen atom, and the following groups: hydroxyl, cyano, nitro, Ci_4- alkyl, C1-4-alkoxy, C1-4-thioalkyl, C1-3-f luoroalkyl, Ca-3- f luoroalkoxy, C1-3-f luorothioalkyl, phenyloxy, benzyloxy, piperidyl, pyrrolidinyl, morpholinyl, NH2, NHR6, NR6R7, NHCOR6, COR6, CO2Rs, SO2R6, -O- (C1-3- alkylene)-O-, 4-piperazinyl optionally substituted with a Cx-3-alkyl or with a benzyl; and R6 and R7 represent, independently of one another, a C1-3-alkyl group or a phenyl. Among the compounds of general formula (I) , a fifth family of compounds consists of the compounds for which: n represents an integer between 1 and 6; A is chosen from one or more groups X, Y and/or Z; X represents a C1-2-alkylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycolalkyl-1-6-alkylene groups; Y represents a C2-alkenylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; or a group -C≡C- 7 Z represents a C3-7-cycloalkyl group of formula: m represents an integer ranging from 1 to 5; p and q represent integers and are defined such that p+q is a number ranging from 1 to 5; R1 represents a hydrogen atom, a halogen atom, or a hydroxyl, cyano, nitro, C1-3-alkyl, C1-3-alkoxy, C1-3- thioalkyl, C1-3-f luoroalkyl, C1-3-fluoroalkoxy or C1-3- fluorothioalkyl group; R2 represents a hydrogen atom, or a phenyl or phenyloxy group, this group being optionally substituted with one or more substituents chosen from a halogen atom, and the following groups: hydroxyl, cyano, nitro, C1-4-alkyl, C1-4-alkoxy, C1-4-thioalkyl, C1-3-f luoroalkyl, C1-3-f luoro- alkoxy, C1-3-f luorothioalkyl, phenyloxy, benzyl oxy, piperidyl, pyrrolidinyl, morpholinyl, NH2, NHR6, NR6R7, NHCOR6, COR6, CO2R6, SO2R6, -O-(C1-3-alkylene)-O-, 4- piperazinyl optionally substituted with a C1-3-alkyl or with a benzyl; R3 represents either a 2,2,2-trifluoroethyl group, or a phenyl group optionally substituted with one or more halogen atoms, or cyano, nitro, C1-3-alkyl, C1-3- alkoxy, trifluoromethyl or trifluoromethoxy groups, and R6 and R7 represent, independently of one another, a C1-3-alkyl group or a phenyl; 2,2,2-trifluoroethyl benzylcarbamate being excluded. Among the compounds of general formula (I) , a sixth family of compounds consists of the compounds for which: n represents an integer between 1 and 6; A is a group X; the groups A being identical to or different from one another when n is an integer between 2 and 6; X represents a C1-2-alkylene group optionally- substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; R1 represents a hydrogen atom, a halogen atom, or a hydroxyl, cyano, nitro, C1-3-alkyl, C1-3-alkoxy, C1-3- thioalkyl, C1-3-f luoroalkyl, C1-3 luoroalkoxy or C1-3- fluorothioalkyl group; R2 represents a hydrogen atom, a halogen atom, or a cyano, nitro, hydroxyl, C1-3-alkyl, C1-3-alkoxy, C1-3-thioalkyl, C1-3-f luoroalkyl, C1-3-f luoroalkoxy, C1-3- fluorothioalkyl group, or a group chosen from a phenyl, naphthalenyl, biphenyl, phenylethylenyl, naphthylethylenyl, pyridinyl, pyrimidinyl, pyrazinyl, pyridazinyl, triazinyl, indanyl, indenyl, quinolinyl, isoquinolinyl, quinazolinyl, quinoxalinyl, phthalazinyl, cinnolinyl, thienyl, furyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, thiadiazolyl, oxadiazolyl, triazolyl, benzothienyl, benzofuryl, dibenzofuryl, benzimidazolyl, benzo- triazolyl, indolyl, isoindolyl, indazolyl, benzoxazolyl, benzisoxazolyl, benzothiazolyl, benziso- thiazolyl, dihydroindolyl, pyrrolopyridinyl, furo- pyridinyl, thienopyridinyl, imidazopyridinyl, oxazolopyridinyl, thiazolopyridinyl, pyrazolopyridinyl, isoxazolopyridinyl, isothiazolopyridinyl, tetrahydro- quinolinyl, tetrahydroisoquinolinyl, phenyloxy, phenylthio, phenylsulfonyl, benzoyl, phenylmethoxy, phenylethoxy, phenylpropoxy, naphthalenyloxy, naphthalenylmethoxy, naphthalenylethoxy, naphthalenyl- propoxy, quinolinoxy and isoquinolinoxy, and optionally substituted with one or more substituents chosen from a halogen atom, and the following groups: hydroxyl, cyano, nitro, C1-4-alkyl, C1-4-alkoxy, C1-4-thioalkyl, C1-3-f luoroalkyl, C1-3-f luoroalkoxy, C1-3-f luorothioalkyl, phenyloxy, benzyloxy, piperidyl, pyrrolidinyl, morpholinyl, NH2, NHR6, NR6R7, NHCOR6, COR6, CO2R6, SO2R6, -O- (C1-3-alkylene) -O-, 4-piperazinyl optionally substituted with a C1-3-alkyl or with a benzyl; R3 represents either a 2,2,2-trifluoroethyl group, or a phenyl group optionally substituted with one or more halogen atoms, or cyano, nitro, C1-3-alkyl, C1-3- alkoxy, trifluoromethyl or trifluoromethoxy groups, and R6 and R7 represent, independently of one another, a C1-3-alkyl group or a phenyl; on the condition that: - when R3 represents a 2,2,2-trifluoroethyl group and the group - [A] n- represents a -CH2- group, then R1 is other than a hydrogen atom or than a methoxy group; - when R3 represents an optionally substituted phenyl group and the group - [A]n- represents a -CH2-, -CH2CH2-, -CH(CH3)- or -CH(CH3)-CH2- group; then R1 is other than a hydrogen or chlorine atom or than a methyl or methoxy group, and R2 is other than a hydrogen atom. The compounds of general formula (I) can comprise one or more asymmetrical carbons. They can exist in the form of enantiomers or of diastereoisomers. These enantiomers and diastereoisomers, and also mixtures thereof, including racemic mixtures, are part of the invention. The compounds of formula (I) can exist in the form of bases or of addition salts with acids. Such addition salts are part of the invention. These salts are advantageously prepared with pharmaceutically acceptable acids, but the salts of other acids useful, for example, for the purification or the isolation of the compounds of formula (I) are also part of the invention. The compounds of general formula (I) can be in the form of hydrates or of solvates, i.e. in the form of associations or of combinations with one or more molecules of water or with a solvent. Such hydrates and solvates are also part of the invention. In the context of the invention: the expression "Ct-Z where t and z can have the values from 1 to 12" is intended to mean a carbon- based chain that can have from t to z carbon atoms; for example, "C1-3" is intended to mean a carbon-based chain which can have from 1 to 3 carbon atoms; the term "alkyl" is intended to mean a linear or branched, saturated aliphatic group; for example, a C1-3-alkyl group represents a linear or branched carbon-based chain of 1 to 3 carbon atoms, more particularly a methyl, ethyl, propyl or 1-methyl- ethyl; the term "alkylene" is intended to mean a linear or branched, saturated divalent alkyl group; for example, a C1-3-alkylene group represents a linear or branched divalent carbon-based chain of 1 to 3 carbon atoms, more particularly a methylene, ethylene, 1-methylethylene or propylene; the term "cycloalkyl" is intended to mean a cyclic alkyl group; for example, a C3-5-cycloalkyl group represents a cyclic carbon-based group of 3 to 5 carbon atoms, more particularly a cyclopropyl, cyclobutyl or cyclopentyl; the term "alkenylene" is intended to mean a divalent unsaturated aliphatic group, more particularly an ethylene; the term "alkoxy" is intended to mean an -O-alkyl group comprising a linear or branched, saturated aliphatic chain; the term "thioalkyl" is intended to mean an -S- alkyl group comprising a linear or branched, saturated aliphatic chain; the term "fluoroalkyl" is intended to mean an alkyl group in which one or more hydrogen atoms have been substituted with a fluorine atom; the term "fluoroalkoxy" in intended to mean an alkoxy group in which one or more hydrogen atoms have been substituted with a fluorine atom; the term "fluorothioalkyl" is intended to mean a thioalkyl group in which one or more hydrogen atoms have been substituted with a fluorine atom; the term "halogen atom" is intended to mean a fluorine, a chlorine, a bromine or an iodine. The compounds of the invention can be prepared according to various methods, illustrated by the schemes which follow. Thus, a first method (scheme 1) for preparing the compounds of general formula (I) consists in reacting an amine of general formula (II), in which R1, R2, n and A are as defined above, with a carbonate of general formula (III), in which U represents a hydrogen atom or a nitro group and R3 is as defined above, in a solvent such as toluene or dichloroethane, at a temperature of between 0 and 80°C. According to a second method, the compounds of general formula (I) for which R3 represents more particularly an optionally substituted phenyl can be prepared by reacting an amine of general formula (II), as defined above, with an aryl chlorof ormate of general formula (IIIa) where R3 represents a phenyl group optionally substituted with one or more halogen atoms, or cyano, nitro, C1-3-alkyl, C1-3-alkoxy, trif luoromethyl or trifluoromethoxy groups, in a solvent such as dichloromethane or dichloroethane in the presence of a base such as triethylamine or diisopropylethylamine, at a temperature of between 0°C and the reflux temperature of the solvent. The carbonates of general formula (III) can be prepared according to any method described in the literature, for example by reaction of an alcohol of general formula HOR3 with phenyl chloroformate or para- nitrophenyl chloroformate, in the presence of a base such as triethylamine or diisopropylethylamine. The compounds of general formulae (II) and (IIIa) are commercially available or described in the literature, or else can be prepared according to methods which are described therein or which are known to those skilled in the art. When R2 represents a group of aryl or heteroaryl type in a compound of formula (I) or (II), the introduction of R2 onto the phenyl ring can be carried out by reacting a derivative of a compound of general formula (I) or (II) in which the phenyl ring bears a chlorine, bromine or iodine atom or a trif late group, in the position where it is desired to introduce R2, with an aryl- or heteroaryl boronic acid derivative in accordance with the Suzuki reaction conditions (Chem. Rev. (1995), 95, 2457-2483; Angew. Chem. Int., Ed. (1999), 38, 3387-3388), or with an aryl- or heteroaryl trialkyltin derivative in accordance with the Stille reaction conditions (Angew. Chem. Int. Ed. Engl. (1986), 25, 508-524). The following examples illustrate the preparation of some compounds of the invention. They are not limiting and merely illustrate the invention. The NMR spectra and/or the LC-MS (Liquid Chromatography coupled to Mass Spectroscopy) confirm the structures and the purities of the compounds obtained. Mp (°C) represents the melting point in degrees Celsius. The numbers indicated between parentheses in the titles of the examples correspond to those of the 1st column of the table hereinafter. The IUPAC nomenclature (International Union of Pure and Applied Chemistry) was used to name the compounds in the following examples. For example, for the biphenyl group, the following numbering was observed: Example 1 (Compound No. 1) 2,2,2-Trifluoroethyl 1,1'-biphenyl-4-ylmethylcarbamate 0.119 ml (1.64 mmol) of 2,2,2-trifluoroethanol and 0.306 ml (1.49 mmol) of N,N-diisopropylethylamine are added, dropwise and at ambient temperature, to a solution of 0.3 g (1.49 mmol) of para-nitrophenyl chloroformate in 15 ml of methylene chloride. The mixture is stirred at ambient temperature for 2 h, and then 0.275 g (1.5 mmol) of 4-phenylbenzylamine is added. N,N-Diisopropyleth.ylamine is subsequently added, dropwise and at ambient temperature, until the precipitate which has formed disappears. The transparent solution thus obtained is stirred at ambient temperature for 1 h. The reaction medium is diluted with a further 10 ml of methylene chloride and washing is carried out with a saturated aqueous ammonium chloride solution and with a saturated aqueous sodium chloride solution. The phases are separated and the organic phase is dried over sodium sulfate. The product is filtered, the filtrate is concentrated under reduced pressure and the residue is purified by silica gel chromatography with methylene chloride. 0.215 g of white solid is obtained. LC-MS: 310 Mp(°C): 123-125°C 1H NMR (DMSO-d6) δ(ppm) : 8.25 (t, 1H) ; 7.75-7.30 (m, 9H); 4.65 (q, 2H); 4.25 (d, 2H). Example 2 (Compound No. 19) 2,2,2-Trifluoroethyl 2 -(1,1'-biphenyl-4-yl)ethyl- carbamate The procedure is carried out in a manner similar to Example 1, replacing the 4-phenylbenzylamine with 2- (4- biphenyl)ethylamine. 0.311 g of white solid is obtained. LC-MS: 324 Mp(°C): 79-81°C 1H NMR (DMSO-dg) δ (ppm) : 7.80-7.20 (m, 10H) ; 4.65 (q, 2H); 3.3 0 (m, 2H) ; 2.75 (t, 2H). Example 3 (Compound No. 10) 2,2,2-Trifluoroethyl 4-phenyloxybenzylcarbamate The procedure is carried out in a manner similar to Example 1, replacing the 4-phenylbenzylamine with 4-phenyloxybenzylamine. 0.252 g of white solid is obtained. LC-MS: 326 Mp(°C): 145-148°C 1HNMR(DMSO-d6) δ(ppm): 8.15 (t, 1H) ; 7.40-6.90 (m, 9H) ; 4.65 (q, 2H); 4.20 (d, 2H). Example 4 (Compound No. 3) 4-Fluorophenyl 1,1'-biphenyl-4-ylmethylcarbamate 0.069 ml (0.522 mmol) of 4-fluorophenyl chloroformate and 0.149 ml (0.82 mmol) of N,N-diisopropylethylamine are added, dropwise and at ambient temperature, to a solution of 0.107 g (0.58 mmol) of 4-phenylbenzylamine in 4 ml of methylene chloride. The mixture is stirred at ambient temperature for 1 h. The reaction medium is diluted with a further 2 ml of methylene chloride and washed with a saturated aqueous ammonium chloride solution and with a saturated aqueous sodium chloride solution. The phases are separated and the organic phase is filtered through a hydrophobic sintered glass funnel. The filtrate is concentrated under reduced pressure and the solid residue is washed with 5 ml of diisopropyl ether. 0.136 g of white solid is obtained. LC-MS: 322 Mp(°C): 155-157°C 1H NMR(DMS0-d6) δ(ppm) : 8.30 (t, 1H) ; 7.70-7.10 (m, 13H); 4.30 (d, 2H). Example 5 (Compound No. 26) 4-Methylphenyl 2-(1,1'-biphenyl-4-yl)ethylcarbamate The procedure is carried out in a manner similar to Example 4, replacing the 4-phenylbenzylamine with 2-(4- biphenyl)ethylamine and the 4-fluorophenyl chloro- formate with 4-methylphenyl chloroformate. 0.126 g of white solid is obtained. LC-MS: 332 Mp(°C): 172-174°C 1H NMR(DMSO-d6) δ(ppm) : 7.75 (t, 1H) ; 7.70-7.30 (m, 9H) ; 7.10 (d, 2H); 6.90 (d, 2H); 3.30 (m, 2H); 2.80 (t, 2H); 2.25 (s, 3H). Example 6 (Compound No. 16) 4-Methoxyphenyl 4-phenyloxybenzylcarbamate The procedure is carried out in a manner similar to Example 4, replacing the 4-phenylbenzylamine with 4-phenyloxybenzylamine and the 4-fluorophenyl chloroformate with 4-methoxyphenyl chloroformate. 0.137 g of white solid is obtained. LC-MS: 350 Mp(°C): 89-91°C 1H NMR(DMS0-d6) δ(ppm) : 8.20 (t, 1H) ; 7.45-7.25 (m, 4H) ; 7.20-6.80 (m, 9H) ; 4.25 (d, 2H) ; 3.75 (s, 3H) . The following table illustrates the chemical structures and the physical properties of some compounds according to the invention. In this table, "n.d." signifies that the melting point could not be determined (product in the form of a gum, for example). The compounds of the invention were subjected to pharmacological assays to determine their inhibitory effect on the FAAH enzyme (fatty acid amido hydrolase) . The inhibitory activity was demonstrated in a radioenzymatic assay based on measuring the product of hydrolysis (ethanolamine [1-3H] ) of anandamide [ethanolamine 1-3H] by FAAH (Life Sciences (1995), 56, 1999-2005) and (Journal of Pharmacology and Experimented Therapeutics (1997), 283, 729-734). Thus, mouse brains (minus the cerebellum) are removed and conserved at -80°C. Membrane homogenates are prepared extemporaneously by homogenization of the tissues with a Polytron in a 10mM Tris-HCl buffer (pH 8.0) containing 150 mM NaCl and 1 mM EDTA. The enzymatic reaction is subsequently carried out in 70 µl of buffer containing fatty acid-free bovine serum albumin (1 mg/ml) . The compounds tested, at various concentrations, anandamide [ethanolamine 1-3H] (specific activity of 15-20 Ci/mmol) diluted to 10 /xM with cold anandamide, and the membrane preparation (400 µg of frozen tissue per assay) are added successively. After 15 minutes at 25°C, the enzymatic reaction is stopped by adding 14 0 µl of chloroform/methanol (2:1). The mixture is stirred for 10 minutes and then centrifuged for 15 minutes at 3500 g. An aliquot (30 µl) of the aqueous phase containing the ethanolamine [1-3H] is counted by liquid scintillation. Under these conditions, the most active compounds of the invention exhibit IC50 values (concentration that inhibits 50% of the control enzymatic activity of FAAH) between 0.001 and 1 µM. It therefore appears that the compounds according to the invention have an inhibitory activity on the FAAH enzyme. The FAAH enzyme (Chemistry and Physics of Lipids, (2000), 108, 107-121) catalyses the hydrolysis of endogenous derivatives of amides and of esters of various fatty acids such as N-arachidonoylethanolamine (anandamide) , N-palmitoylethanolamine, N-oleylethanol- amine, oleamide or 2-arachidonoylglycerol. These derivatives exert various pharmacological activities by interacting, inter alia, with cannabinoid and vanilloid receptors. The compounds of the invention block this degradation pathway and increase the tissue content of these endogenous substances. They can be used in this respect in the prevention and treatment of pathologies in which endogenous cannabinoids and/or any other substrates metabolized by the FAAH enzyme are involved. Mention may, for example, be made of the following diseases and conditions: pain, in particular acute or chronic pain of neurogenic type: migraine, neuropathic pain including the forms associated with the herpesvirus and with diabetes; acute or chronic pain associated with inflammatory diseases: arthritis, rheumatoid arthritis, osteoarthritis, spondylitis, gout, vasculitis, Crohn's disease, irritable bowel syndrome; acute or chronic peripheral pain: dizziness, vomiting, nausea, in particular those subsequent to chemotherapy; eating disorders, in particular anorexia and cachexia of various natures; neurological and psychiatric pathologies: shaking, dyskinesia, dystonia, spasticity, obsessive compulsive disorders, Tourette's syndrome, all forms of depression and anxiety of any nature and origin, mood disorders, psychoses; acute and chronic neurodegenerative diseases: Parkinson's disease, Alzheimer's disease, senile dementia, Huntington's chorea, lesions related to cerebral ischemia and to cranial and medullary traumas; epilepsy; sleeping disorders, including sleep apnoea; cardiovascular diseases, in particular hypertension, cardiac arrhythmias, arteriosclerosis, heart attack, cardiac ischemias; renal ischemia; cancers: benign skin tumors, papillomas and brain tumors, prostate tumors, brain tumors (glioblastomas, medulloepitheliomas, medulloblastomas, neuroblastomas, tumors of embryonic origin, astrocytomas, astroblastomas, ependyomas, oligodendrogliomas, plexus tumors, neuroepitheliomas, epiphyseal tumors, ependymoblastomas, malignant meningiomas, sarcomatoses, malignant melanomas, schwannomas); immune system disorders, in particular autoimmune diseases: psoriasis, lupus erythematosus, connective tissue diseases or connectivitis, Sjogren's syndrome, ankylosing spondylarthritis, undifferentiated spondylarthritis, Behcet's disease, hemolytic auto- immune anemia, multiple sclerosis, amyotrophic lateral sclerosis, amyloses, transplant rejection, diseases affecting the plasmocyte line; allergic diseases: immediate or delayed hyper- sensitivity, allergic rhinitis or conjunctivitis, contact dermatitis; parasitic, viral or bacterial infectious diseases: AIDS, meningitis; inflammatory diseases, in particular articular diseases: arthritis, rheumatoid arthritis, osteo arthritis, spondylitis, gout, vasculitis, Crohn's disease, irritable bowel syndrome; osteoporosis ,- ocular conditions: ocular hypertension, glaucoma; pulmonary conditions: respiratory tract diseases, bronchospasms, coughs, asthma, chronic bronchitis, chronic respiratory tract obstruction, emphysema; gastrointestinal diseases: irritable bowel syndrome, intestinal inflammatory disorders, ulcers, diarrhea; urinary incontinence and bladder inflammation. The use of the compounds according to the invention for preparing a medicinal product for use in the treatment of the pathologies mentioned above is an integral part of the invention. The use of the following compounds for preparing a medicinal product for use in the treatment of the pathologies mentioned above is also an integral part of the invention: - 2,2,2-trifluoroethyl benzylcarbamate; - 2,2,2-trifluoroethyl 4-methoxybenzylcarbamate; - 4-nitrophenyl 2 -[4-phenylmethoxy)phenyl]ethyl- carbamate, - 4-chloro-2-nitrophenyl 2-(4-chlorophenyl)ethyl- carbamate; - 4-nitrophenyl 2-(3,4-dimethoxyphenyl)ethylcarbamate; - phenyl 2-(3,4-dimethoxyphenyl)ethylcarbamate; - 4-cyanopheny1 2-(4-methylphenyl)ethylcarbamate; - 2,4,5-trichlorophenyl 2-(4-chlorophenyl)ethyl- carbamate; - phenyl 4-chlorobenzylcarbamate; - phenyl 4-methoxybenzylcarbamate; - 4-fluorophenyl 2-(4-methoxyphenyl)ethylcarbamate; - phenyl 3-nitrobenzylcarbamate; - 4-cyanophenyl 4-methoxybenzylcarbamate; - phenyl 3-chlorobenzylcarbamate; - phenyl 3,4-dichlorobenzylcarbamate; - 4-nitrophenyl 2-(4-hydroxyphenyl)ethylcarbamate, - phenyl 2-[4-(2-ethyl-5,7-diimethyl-3H-imidazo- [4,5-b]pyridin-3-yl)phenyl]ethylcarbamate; - phenyl 2-[4-(2-amino-4-thiazolyl)phenyl]ethyl- carbamate; - 2,3,4,5,6-pentafluorophenyl 4-bromobenzylcarbamate. A subject of the invention is also medicinal products which comprise a compound of formula (I), or a salt, or else a hydrate or a solvate, that is pharmaceutically acceptable, of the compound of formula (I). These medicinal products find their use in therapeutics, in particular in the treatment of the pathologies mentioned above. A subject of the invention is also medicinal products which comprise a compound chosen from the list of compounds below, or a salt, or else a hydrate or a solvate, that is pharmaceutically acceptable, of this compound: - 2,2,2-trifluoroethyl benzylcarbamate; - 2,2,2-trifluoroethyl 4-methoxybenzylcarbamate; - 4-nitrophenyl 2-[4-phenylmethoxy)phenyl]ethyl- carbamate, - 4-chloro-2-nitrophenyl 2-(4-chlorophenyl)ethyl- carbamate; - 4-nitrophenyl 2-(3,4-dimethoxyphenyl)ethylcarbamate; - phenyl 2-(3,4-dimethoxyphenyl)ethylcarbamate; - 4-cyanophenyl 2-(4-methylphenyl)ethylcarbamate; - 2,4,5-trichlorophenyl 2-(4-chlorophenyl)ethyl- carbamate; - phenyl 4-chlorobenzylcarbamate; - phenyl 4-methoxybenzylcarbamate; - 4-fluorophenyl 2-(4-methoxyphenyl)ethylcarbamate; - phenyl 3-nitrobenzylcarbamate; - 4-cyanophenyl 4-methoxybenzylcarbamate; - phenyl 3-chlorobenzylcarbamate; - phenyl 3,4-dichlorobenzylcarbamate; - 4-nitrophenyl 2-(4-hydroxyphenyl)ethylcarbamate; - phenyl 2-[4-(2-ethyl-5,7-diimethyl-3H-imidazo- [4,5-b]pyridin-3-yl)phenyl]ethylcarbamate; - phenyl 2-[4-(2-amino-4-thiazolyl)phenyl]ethyl- carbamate; - 2,3,4,5,6-pentafluorophenyl 4-bromobenzylcarbamate. These medicinal products find their use in thera- peutics, in particular in the treatment of the pathologies mentioned above. According to another of its aspects, the present invention relates to pharmaceutical compositions containing, as active ingredient, at least one compound according to the invention. These pharmaceutical compositions contain an effective dose of a compound according to the invention, or a salt, or a hydrate, or a solvate, that is pharmaceutically acceptable, of said compound, and, optionally, one or more excipients that are pharmaceutically acceptable. According to another of its aspects, the present invention relates to pharmaceutical compositions containing, as active ingredient, at least one compound chosen from the list of compounds below. These pharmaceutical compositions contain an effective dose of a compound chosen from the list of compounds below, or a salt, or a hydrate, or a solvate, that is pharmaceutically acceptable, of said compound, and, optionally, one or more excipients that are pharma- ceutically acceptable: - 2,2,2-trifluoroethyl benzylcarbamate; - 2,2,2-trifluoroethyl 4-methoxybenzylcarbamate; - 4-nitrophenyl 2-[4-phenylmethoxy)phenyl]ethyl- carbamate, - 4-chloro-2-nitrophenyl 2-(4-chlorophenyl)ethyl- carbamate; - 4-nitrophenyl 2-(3,4-dimethoxyphenyl)ethylcarbamate; - phenyl 2- (3 ,4-dimethoxyphenyl) ethylcarbamate,- - 4-cyanophenyl 2-(4-methy1phenyl)ethylcarbamate;r - 2,4,5-trichlorophenyl 2-(4-chlorophenyl)ethyl- carbamate ; - phenyl 4-chlorobenzylcarbamate; - phenyl 4-methoxybenzylcarbamate; - 4-fluorophenyl 2-(4-methoxyphenyl)ethylcarbamate; - phenyl 3-nitrobenzylcarbamate; - 4-cyanophenyl 4-methoxybenzylcarbamate; - phenyl 3-chlorobenzylcarbamate; - phenyl 3,4-dichlorobenzylcarbamate; - 4-nitrophenyl 2-(4-hydroxyphenyl)ethylcarbamate; - phenyl 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo- [4,5-b]pyridin-3-yl)phenyl]ethylcarbamate; - phenyl 2-[4-(2-amino-4-thiazolyl)phenyl]ethyl- carbamate ; - 2,3,4,5,6-pentafluorophenyl 4-bromobenzylcarbamate. Said excipients are chosen, according to the pharma- ceutical form and the method of administration desired, from the usual excipients that are known to those skilled in the art. In the pharmaceutical compositions of the present invention for oral, sublingual, subcutaneous, intra- muscular, intravenous, topical, local, intrathecal, intranasal, transdermal, pulmonary, ocular or rectal administration, the active ingredient of formula (I) above or one of the compounds below: - 2,2,2-trifluoroethyl benzylcarbamate; - 2,2,2-trifluoroethyl 4-methoxybenzylcarbamate; - 4-nitrophenyl 2-[4-phenylmethoxy)phenyl]ethyl- carbamate, - 4-chloro-2-nitrophenyl 2-(4-chlorophenyl)ethyl- carbamate; - 4-nitrophenyl 2-(3,4-dimethoxyphenyl)ethylcarbamate; - phenyl 2-(3,4-dimethoxyphenyl)ethylcarbamate; - 4-cyanophenyl 2-(4-methylphenyl)ethylcarbamate; - 2,4,5-trichlorophenyl 2-(4-chlorophenyl)ethyl- carbamate; - phenyl 4-chlorobenzylcarbamate; - phenyl 4-methoxybenzylcarbamate; - 4-fluorophenyl 2-(4-methoxyphenyl)ethylcarbamate; - phenyl 3-nitrobenzylcarbamate; - 4-cyanophenyl 4-methoxybenzylcarbamate; - phenyl 3-chlorobenzylcarbamate; - phenyl 3,4-dichlorobenzylcarbamate; - 4-nitrophenyl 2-(4-hydroxyphenyl)ethylcarbamate; - phenyl 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo- [4, 5-b]pyridin-3-yl)phenyl]ethylcarbamate; - phenyl 2-[4-(2-amino-4-thiazolyl)phenyl]ethyl- carbamate; - 2,3,4,5,6-pentafluorophenyl 4-bromobenzylcarbamate; or its possible salt, solvate or hydrate, can be administered in unit administration form as a mixture with conventional pharmaceutical excipients, to animals and to human beings for the prophylaxis or the treatment of the disorders or of the diseases above. Suitable unit administration forms comprise oral administration forms such as tablets, soft or hard gelatin capsules, powders, granules, chewing gums and oral solutions or suspensions, sublingual, buccal, intratracheal, intraocular and intranasal admini- stration forms, forms for administration by inhalation, subcutaneous, intramuscular or intravenous administration forms, and rectal or vaginal admini- stration forms. For topical application, the compounds according to the invention can be used in creams, ointments or lotions. By way of example, a unit administration form of a compound according to the invention in tablet form can comprise the following components: Compound according to the invention 50.0 mg Mannitol 223.75 mg Sodium croscarmellose 6.0 mg Corn starch 15.0 mg Hydroxypropylmethylcellulose 2.25 mg Magnesium stearate 3.0 mg Said unit forms contain doses so as to allow a daily administration of 0.01 to 20 mg of active ingredient per kg of bodyweight, according to the pharmaceutical form. There may be specific cases where higher or lower doses are appropriate, such doses are also part of the invention. According to the usual practice, the dosage suitable for each patient is determined by the physician according to the method of administration, and the weight and response to said patient. According to another of its aspects, the invention also relates to a method of treatment of the pathologies indicated above, which comprises the administration of an effective dose of a compound according to the invention, of one of its salts that are pharmaceutically acceptable, or of a solvate or a hydrate of said compound. WE. CLAIM: 1. A compound of the formula (I); in which n represents an integer between 1 and 6; A is a group X; X represents a C1-2-alkylene group optionally substituted with one or more C1-12-alkyl, C3-7-cycloalkyl or C3-7-cycloalkyl-C1-6-alkylene groups; R1 represents a hydrogen atom, a halogen atom, or a hydroxyl, cyano, nitro, C1-3-alkyl, C1-3-alkoxy, C1-3- thioalkyl, C1-3-fluoroalkyl, C1-3-f luoroalkoxy or C1-3- fluorothioalkyl group; R2 represents a hydrogen atom, a halogen atom, or a cyano, nitro, hydroxyl, C1-3-alkyl, C1-3-alkoxy, C1-3- thioalkyl, C1-3-fluoroalkyl, C1-3-fluoroalkoxy or C1-3- fluorothioalkyl group; or a group chosen from a phenyl, naphthalenyl biphenyl, phenylethylenyl, naphthylethylenyl, phenyloxy, phenylthxo, phehylsulfonyl, benzoyl phenylmethoxy, phenylethoxy, phenylpropoxy, naphthalenyloxy, naphthalenylmethoxy, naphthalenylethoxy, and naphthalenylpropoxy, and optionally substituted with one or more substituents chosen from a halogen atom, and the following groups: hydroxyl, cyano, nitro, C1-4- alkyl, C1-4-alkoxy, C1-4-thioalkyl, C1-3-fluoroalkyl, C1-3- fluoroalkoxy, C1-3-fluorothioalkyl, phenyloxy, benzyloxy, piperidyl, pyrrolidinyl, morpholinyl, NH2, NHR6, NR6R7; NHCOR6, COR6, CO2R6, SO2R6, -O-(C1-3- alkylene)-O-, 4-piperazinyl optionally substituted with a C1-3-alkyl or with a benzyl, R3 represents either a 2,2,2-trifluoroethyl group, or a phenyl group optionally substituted with one or more halogen atoms or cyano, nitro, C1-3-alkyl, C1-3- alkoxy, trifluoromethyl or. trifluoromethoxy groups, and R6 and R7 represent, independently of one another, a C1-3-alkyl group or a phenyl; with the proviso that: when R3 represents 2,2,2-trifluoroethyl group and the group - [A]n- represents a -CH2- group, then R1 is other thana hydrogen atom or a methoxy group; and when R3 represents an optionally substituted phenyl group and the group - [A]n- represents a -CH2-, -CH2CH2-, -CH(CH3)- or -CH(CH3)-CH2- group, then R1 is other than a hydrogen or chlorine atom or a methyl or methoxy group and R2 is other than a hydrogen atom; and wherein said compound is in the form of a base, or an addition salt with an acid. 2. A process for preparing a compound of formula (I) in which R1, R2, R3, A and n are as defined according to claim 1, comprising the step of: reacting an amine of formula (II) in which R1, R2, n and A are as defined in formula (I) , with a carbonate of formula (III) in which U represents a hydrogen atom or a nitro group and R3 is as defined in formula (I). 3. A process for preparing a compound of formula (I) in which R1, R2, A and n are aa defined according to claim 1, and R3 represents a phenyl group optionally substituted with one or more halogen atoms, or cyano, nitro, C1-3- alkyl, C1-3-alkoxy, trifluoromethyl or trifluoromethoxy groups, comprising the step of reacting an amine of general formula (II) in which R1, R2, n and A are as defined in general formula (I) , with an aryl chloroformate of general formula (IIIa) in which R3 represents a phenyl group optionally substituted with one or more halogen atoms, or cyano, nitro, C1-3-alkyl, C1-3-alkoxy, trifluoromethyl or trifluoromethoxy groups. 4. A pharmaceutical composition comprising at least one compound of formula (I) as claimed in claim 1, in the form of a base, or a pharmaceutically acceptable salt, in combination with one or more pharmaceutically acceptable excipients. 5. The pharmaceutical composition as claimed in claim 4, wherein compound of formula (I) is selected from the group consisting of: - 2, 2, 2-trifluoroethyl benzylcarbamate; - 2,2,2-trifluorbethyl 4-methoxybenzylcarbamate; - 4-nitrophenyl 2- [4-(phenylmethoxy) phenyl] ethyl- carbamate ; - 4-chloro-2-nitrophenyl 2-(4-(chlorophenyl)ethyl- carbamate; - phenyl 2 - (3,4 -dimethoxyphenyl) ethylcarbamate ; - 2,4,5-trichlorophenyl 2-(4-chlorophenyl)ethyl- carbamate ; - phenyl 4-chlorobenzylcarbamate; - phenyl 4-methoxybenzylcarbamate; - 4 -fluorophenyl 2 -(4-methoxyphenyl)ethylcarbamate; - phenyl 3-nitrobenzylcarbamate; - 4-cyanophenyl 4-methoxybenzylcarbamate; - phenyl 3-chlorobenzylcarbamate; - phenyl 3,4-dichlorobenzylcarbamate; - 4-nitrophenyl 2-(4-hydroxyphenyl)ethylcarbamate; - phenyl 2-[4-(2-amino-4-thiazolyl) phenyl]ethyl- carbamate; and - 2,3,4,5,6-pentafluorophenyl 4 -bromobenzylcarbamate; in the form of a base, or a pharmaceutically acceptable salt, hydrate or a solvate thereof. 6. The compound of formula (I) as claimed in claim 1, in the form of a base, or a pharmaceutically acceptable salt thereof. 7. The compound of formula (I) as claimed in claim 1, which is chosen from the following compounds: - 2,2,2-trifluoroethyl benzylcarbamate; - 2,2,2-trifluoroethyl 4-methoxybenzylcarbamate; - 4 -nitrophenyl 2-[4 - (pheriylmethoxy) phenyl] ethyl - carbamate; - 4-chloro-2-nitrophenyl 2-(4-(chlorophenyl)ethyl- carbamate ; - phenyl 2 - (3,4-dimethoxyphenyl)ethylcarbamate; - 2,4,5-trichlorophenyl 2-(4-chlorophenyl)ethyl- carbamate; - phenyl 4-chlorobenzylcarbamate; - phenyl 4-methoxybenzylcarbamate; - 4-fluorophenyl 2-(4-methoxyphenyl) ethylcarbamate; - phenyl 3-nitrobenzylcarbamate; - 4-cyanophenyl 4-methoxybenzylcarbamate; - phenyl 3 -chlorobenzylcarbamate; - phenyl 3,4-dichlorobenzylcarbamate; - 4-nitrophenyl 2-(4-hydroxyphenyl)ethylcarbamate; - phenyl 2-[4-(2-amino-4-thiazolyl)phenyl]ethyl- carbamate; - 2,3, 4,5,6-pentafluorophenyl 4-bromobenzylcarbamate; in the form of a base, or a pharmaceutically acceptable salt thereof. ARYLALKYLCARBAMATE DERIVATIVES AND PROCESSES FOR PREPARATION THEREOF (57) Abstract: The invention relates to a compound having general formula (I), wherein: n represents an integer of between 1 and 6; A is selected from one or more X, Y and/or Z groups; X represents an optionally-substituted C1-2-alkylene group; Y represents an optionally-substituted C2-alkenylene group or a -C=C- group; Z represents a C3-7-cycloalkyl group having formula (II) in which m represents an integer of between 1 and 5, and p and q represent integers and are defined such that p+q equals a number of between 1 and 5; R1 represents a hydrogen atom, a halogen atom or a hydroxyl, cyano, nitro, C1-3-alkyl, C1-3-alkoxy, C1-3-thioalkyl, C1-3-fluoroalkyl, C1-3-fluoroalkoxy, C1-3-fluorothioalkyl group; R2 represents a hydrogen atom, a halogen atom or a cyano, nitro, hydroxyl, C1-3-alkyl, C1-3-alkoxy, C1-3-thioalkyl, C1-3-fluoroalkyl, C1-3-fluoroalkoxy, C1-3-fluorothioalkyl group, or an optionally-substituted aromatic or heteroaromatic group; R3 represents either a 2,2,2-trifluoroethyl group or an optionally-substituted phenyl group; and R6 and R7 represent independently of each other a C1-3-alkyl group, a phenyl; said compound taking the form of a base, an acid addition salt, a hydrate or a solvate. The invention also relates to the use of the compound in therapeutics. |
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00779-kolnp-2006-description complete.pdf
00779-kolnp-2006-international exm report.pdf
00779-kolnp-2006-international publication.pdf
00779-kolnp-2006-priority document.pdf
779-KOLNP-2006-AMANDED CLAIMS.pdf
779-KOLNP-2006-CORRESPONDENCE.pdf
779-KOLNP-2006-DESCRIPTION (COMPLETE).pdf
779-KOLNP-2006-EXAMINATION REPORT REPLY RECIEVED.pdf
779-KOLNP-2006-EXAMINATION REPORT.pdf
779-KOLNP-2006-FORM 13-1.1.pdf
779-KOLNP-2006-FORM 13-1.2.pdf
779-KOLNP-2006-GRANTED-ABSTRACT.pdf
779-KOLNP-2006-GRANTED-CLAIMS.pdf
779-KOLNP-2006-GRANTED-DESCRIPTION (COMPLETE).pdf
779-KOLNP-2006-GRANTED-FORM 1.pdf
779-KOLNP-2006-GRANTED-FORM 2.pdf
779-KOLNP-2006-GRANTED-SPECIFICATION.pdf
779-KOLNP-2006-PETITION UNDER RULE 137.pdf
779-KOLNP-2006-REPLY TO EXAMINATION REPORT.pdf
Patent Number | 264782 | |||||||||
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Indian Patent Application Number | 779/KOLNP/2006 | |||||||||
PG Journal Number | 04/2015 | |||||||||
Publication Date | 23-Jan-2015 | |||||||||
Grant Date | 21-Jan-2015 | |||||||||
Date of Filing | 30-Mar-2006 | |||||||||
Name of Patentee | SANOFI AVENTIS | |||||||||
Applicant Address | 174, AVENUE DE FRANCE, PARIS, 75013, FRANCE. | |||||||||
Inventors:
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PCT International Classification Number | C07C 271/48 | |||||||||
PCT International Application Number | PCT/FR2004/002486 | |||||||||
PCT International Filing date | 2004-10-01 | |||||||||
PCT Conventions:
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