Title of Invention	"NUCLEIC ACID VECTOR SYSTEMS BEARING TRANSLATION ENHANCER-ELEMENT "
Abstract	A translation enhancer-driven positive feedback vector system is disclosed which is designed to facilitate identification of a Translational Enhancer Element (TEE) and to provide a means for overexpression of gene products. The system exploits both transcriptional and translational approaches to control the expression levels of genes and/or gene products. Methods are also disclosed for screening libraries of random nucleotide sequences to identify translational elements and for overproduction of proteins, which have uses in both research and industrial environments.

Title of Invention

"NUCLEIC ACID VECTOR SYSTEMS BEARING TRANSLATION ENHANCER-ELEMENT "

Abstract

A translation enhancer-driven positive feedback vector system is disclosed which is designed to facilitate identification of a Translational Enhancer Element (TEE) and to provide a means for overexpression of gene products. The system exploits both transcriptional and translational approaches to control the expression levels of genes and/or gene products. Methods are also disclosed for screening libraries of random nucleotide sequences to identify translational elements and for overproduction of proteins, which have uses in both research and industrial environments.

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http://ipindiaonline.gov.in/patentsearch/GrantedSearch/viewdoc.aspx?id=0ipUrvbzeQLndsJCGoT4Pw==&loc=+mN2fYxnTC4l0fUd8W4CAA==

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Patent Number

268498

Indian Patent Application Number

2002/DELNP/2008

PG Journal Number

36/2015

Publication Date

04-Sep-2015

Grant Date

31-Aug-2015

Date of Filing

07-Mar-2008

Name of Patentee

THE SCRIPPS RESEARCH INSTITUTE

Applicant Address

10550 NORTH TORREY PINES ROAD, LA JOLLA, CALIFORNIA 92037, U.S.A

Inventors:

#	Inventor's Name	Inventor's Address
1	MAURO, VINCENT, P	7311 JUNCUS COURT, SAN DIEGO, CALIFORNIA 92121, U.S.A
2	EDELMAN, GERALD, M	7428 HIGH AVENUE, LA JOLLA, CALIFORNIA 92037, U.S.A
3	ZHOU, WEI	9338 BABUATA ROAD, # 77, SAN DIEGO, CALIFORNIA 92129, U.S.A

PCT International Classification Number

C12Q 1/68

PCT International Application Number

PCT/US2006/033017

PCT International Filing date

2006-08-23

PCT Conventions:

#	PCT Application Number	Date of Convention	Priority Country
1	60/711,149	2005-08-24	U.S.A.