Title of Invention

"4-(2,6-DICHLORO-BENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXYLIC ACID PIPERIDIN-4-YLAMIDE ACID ADDITION SALTS AS KINASE INHIBITORS"

Abstract The invention provides an acid addition salt of 4-(2,6-dichloro-benzoyIamino)-lH-pyrazole-3-carboxylic acid piperidin-4-ylamide and crystals thereof, the salt being formed with an acid selected from methanesulphonic acid and acetic acid and mixtures thereof. Also provided are the novel uses of salts of 4-(2,6-dichloro-benzoylamino)-lH-pyrazole-3-carboxylic acid piperidin-4-ylamide, processes for the preparation of 4-(2,6-dichloro-benzoylamino)-1 H-pyrazole-3-carboxylic acid piperidin-4-ylamide and its salts and novel chemical interme.
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Patent Number 269504
Indian Patent Application Number 3647/CHENP/2007
PG Journal Number 44/2015
Publication Date 30-Oct-2015
Grant Date 26-Oct-2015
Date of Filing 21-Aug-2007
Name of Patentee ASTEX THERAPEUTICS LIMITED
Applicant Address 436 CAMBRIDGE SCIENCE PARK, MILTON ROAD, CAMBRIDGE CB4 0QA, U.K
Inventors:
# Inventor's Name Inventor's Address
1 WYATT, PAUL, GRAHAM DIVISION OF BIOLOGICAL CHEMISTRY & MOLECULAR, MICROBIOLOGY, UNIVERSITY OF DUNDEE, DOW STREET, DUNDEE DD1 5EH, U.K
2 REES, DAVID, CHARLES 436 CAMBRIDGE SCIENCE PARK, MILTON ROAD, CAMBRIDGE CB4 0QA, U.K
3 VINKOVIC, MLADEN 436 CAMBRIDGE SCIENCE PARK, MILTON ROAD, CAMBRIDGE CB4 0QA, U.K
4 TREWARTHA, GARY 436 CAMBRIDGE SCIENCE PARK, MILTON ROAD, CAMBRIDGE CB4 0QA, U.K
PCT International Classification Number C07D 401/12
PCT International Application Number PCT/GB06/00207
PCT International Filing date 2006-01-20
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 0501475.8 2005-01-22 U.K.
2 60/645,973 2005-01-21 U.K.