| Abstract |
The invention relates to a method for the enantioselective enzymatic reduction of secodione derivatives of general formula (I), wherein the ring structures comprise no, one, or several heteroatom/s, R1 represents hydrogen or a C1-C4 alkyl group, R2 represents hydrogen, a C1-C8 alkyl group, or a protective OH- group known in prior art, such as an ester, R3 represents hydrogen, a methyl group, or a halide, the structural element (A) represents a benzene ring or a C6 ring containing 0, 1, or 2 C-C double bonds, positions 6/7 or 7/8 optionally contain a double bond, and the carbon is independently substituted with hydrogen, a C1-C4 alkyl group, a halide, or a phenyl group in positions 1, 2, 4, 5, 6, 7, 8, 9, 11, 12, and 16. In said method, the ... |