Title of Invention | “METHOD OF SYNTHESIZING SEVOFLURANE” |
---|---|
Abstract | The invention provides a method of synthesizing sevoflurane. The method comprises the following steps that: taking hexafluoro isopropanol as the raw material and reacting it with trioxymethylene (or paraformaldehyde) in the presence of acids to generate di-hexafluoro isopropanol formal derivatives, adding anhydrous aluminum trihalide to generate halomethyl 2, 2,2-trifluoro-1-(trifluoromethyl) ethyl ether, then reacting the halomethyl compound with metal fluoride to form the sevoflurane. The method has low cost, and the reaction condition is easy to implement, and produces sevoflurane in large scale. |
Full Text | PLEASE SEE THE SPECIFICATION ATTACHED |
---|
Patent Number | 272882 | ||||||||
---|---|---|---|---|---|---|---|---|---|
Indian Patent Application Number | 9349/DELNP/2010 | ||||||||
PG Journal Number | 19/2016 | ||||||||
Publication Date | 06-May-2016 | ||||||||
Grant Date | 29-Apr-2016 | ||||||||
Date of Filing | 30-Dec-2010 | ||||||||
Name of Patentee | LUNAN PHARMACEUTICAL GROUP CORPORATION | ||||||||
Applicant Address | No. 209 Hongqi Road Linyi City Shandong Province 276006 China. | ||||||||
Inventors:
|
|||||||||
PCT International Classification Number | C07C | ||||||||
PCT International Application Number | PCT/CN2009/000750 | ||||||||
PCT International Filing date | 2009-07-02 | ||||||||
PCT Conventions:
|