Title of Invention

PURIFICATION OF CARRIER PROTEIN- ANTIGEN COMPLEXES

Abstract A method of isolating and purifying protein polysaccharide conjugates using hydrophobic interaction chromatography. Crude protein polysaccharide conjugate mixtures are subjected to ultrafiltration to remove unreacted protein, and loaded onto a column filled with a suitable hydrophobic resin. Elution is effected with salt solutions of decreasing ionic strength. Protein polysaccharide conjugates substantially free of unconjugated polysaccharide are provided.
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Patent Number 278023
Indian Patent Application Number 1070/MUM/2009
PG Journal Number 52/2016
Publication Date 16-Dec-2016
Grant Date 08-Dec-2016
Date of Filing 22-Apr-2009
Name of Patentee SERUM INSTITUTE OF INDIA PRIVATE LIMITED
Applicant Address 212/2 Off Soli Poonawalla Road Hadapsar Pune 411 028 Maharashtra India.
Inventors:
# Inventor's Name Inventor's Address
1 KAPRE Subhash V. c/o Serum Institute of India Ltd. of 212/2 Off Soli Poonawalla Road Hadapsar Pune 411 028 Maharashtra India.
2 JOGLEKAR Tushar c/o Serum Institute of India Ltd. of 212/2 Off Soli Poonawalla Road Hadapsar Pune 411 028 Maharashtra India.
PCT International Classification Number A61K39/00
PCT International Application Number N/A
PCT International Filing date
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 NA