| Title of Invention | TOOTHPASTE COMPOSITION |
|---|---|
| Abstract | A toothpaste composition comprising a surfactant, an abrasive, a humectant, triglyceride oil, a carboxylated polysaccharide, and a sulphated or sulphonated polysaccharide and the use of a sulphated or sulphonated polysaccharide, in particular a carrageenan, to improve the in-use foam quality of a toothpaste. |
| Full Text | FORM - 2 THE PATENTS ACT, 1970 (39 of 1970) & The Patents Rules, 2003 COMPLETE SPECIFICATION (See Section 10 and Rule 13) TOOTHPASTE COMPOSITION HINDUSTAN UNILEVER LIMITED, a company incorporated under the Indian Companies Act, 1913 and having its registered office at 165/166, Backfoay Reclamation, Mumbai -400 020, Maharashtra, India The following specification particularly describes the invention and the manner in which it is to be performed WO 2008/119605 PCT/EP2008/052445 - 1 - TOOTHPASTE COMPOSITION The present invention relates to toothpaste compositions having superior in use sensory benefits. 5 There are very many toothpaste compositions known in the art. Some of these comprise oils, such a flavouring oils or triglyceride oils. We have found that such compositions can have in use sensory problems because of the effect of the 10 oil. In particular, we have found that the nature of the foam generated by the surfactant present in the toothpaste can be adversely affected. Surprisingly, we have found that superior sensory benefits 15 may be attained via the incorporation of a sulphated or sulphonated polysaccharide and a carboxylated polysaccharide into a toothpaste composition comprising a triglyceride oil. In use sensory benefits, in particular the perceived foam quality of the product, are significantly improved by the 20 present invention. In a first of aspect of the present invention, there is provided a toothpaste composition comprising a surfactant, an abrasive, a humectant, a triglyceride oil, a carboxylated 2 5 polysaccharide, and a sulphated or sulphonated polysaccharide. In a second of aspect of the present invention, there is provided a method of cleaning the teeth comprising brushing 30 with a composition according to the first aspect of the invention. WO 2008/119605 PCT/EP2008/052445 - 2 - In a third of aspect of the present invention, there is provided the use of a sulphated or sulphonated polysaccharide, in particular a carrageenan, to improve the in use foam quality of a toothpaste also comprising a 5 surfactant, an abrasive, a humectant, a triglyceride oil, and a carboxylated polysaccharide. The surfactant used in accordance with the invention may be an anionic, nonionic, cationic, zwitterionic or amphoteric 10 surfactant, or mixtures thereof. Preferably, the surfactant is anionic, in particular an alkali metal alkyl sulphate, and especially sodium lauryl sulphate (SLS). The total amount of surfactant is typically from 0.1 to 10%, 15 in particular from 0.5 to 5%, and especially from 1 to 3% by weight of the total composition. The abrasive used in accordance with the invention is typically a particulate abrasive material such as a silica, 20 alumina, calcium carbonate, dicalciumphosphate, calcium pyrophosphate, hydroxyapatite, trimetaphosphate, insoluble hexametaphosphate, or mixtures thereof. Agglomerated particulate abrasive materials may also be used. Preferred abrasive materials are chalk and silica, in particular 25 silica. The total amount of abrasive is typically from 3 to 60%, in particular from 5 to 40%, and especially from 6% to 20% by weight of the total composition. 30 The humectant used in accordance with the invention is typically a polyol, in particular a polyol selected from WO 2008/119605 PCTYEP2008/052445 - 3 - glycerol, sorbitol, propyleneglycol, xylitol, lactitol, or mixtures thereof. Sorbitol is especially preferred, this material also functioning as a sweetener (vide infra). 5 The total amount of humectant is typically from 1 to 60%, in particular from 5 to 50%, and especially from 10% to 30% by weight of the total composition. The triglyceride oil used in accordance with the invention 10 is preferably sunflower oil, said oil providing a valuable source of Vitamin F to the teeth. With compositions comprising sunflower oil, the sensory benefits of the present invention have been particularly evident. More than one triglyceride oil may be present in the composition. 15 The total amount of triglyceride oil is typically from 0.5%, in particular from 1%, and especially from 1.5% by weight of the total composition. In order that the sensory benefits associated with the triglyceride oil are not too difficult 20 to overcome, the amount of triglyceride oil is typically less than 10%, in particular less 7%, and especially less than 5% by weight of the total composition. The carboxylated polysaccharide used in accordance with the 25 invention is typically a cellulose derivative, in particular a carboxyalkyl cellulose, and especially carboxymethylcellulose (CMC), typically used as its sodium salt (SCMC). The carboxylated polysaccharide typically serves to thicken the toothpaste and also contributes to the 30 sensory properties of the toothpaste. WO 2008/119605 PCT/EP2008/052445 - 4 - The total amount of carboxylated polysaccharide is typically from 0.2%, in particular from 0.5%, and especially from 0.8% by weight of the total composition. The total amount is preferably less than 5%, more preferably less 2%, and most 5 preferably less than 1% by weight of the total composition. The sulphated or sulphonated polysaccharide used in accordance with the invention is typically a sulphated polysaccharide, in particular a linear sulphated 0 polysaccharide, and especially a carrageenan. Of the three main commercial classes of carrageenan (Kappa, ex Kappaphycus cottonii; Iota, ex Eucheuma spinosum; and Lambda, the common source of which is Gigartina); Kappa and Iota are preferred. The sulphated or sulphonated 5 polysaccharide typically serves to thicken the toothpaste and also contributes beneficially to the sensory properties of the toothpaste. The total amount of sulphated or sulphonated polysaccharide 0 is preferably from 0.1%, more preferably from 0.25%, and most preferably from 0.4% by weight of the total composition. The total amount is preferably less than 3%, more preferably less 1.5%, and most preferably less than 0.6% by weight of the total composition. 5 The weight ratio of the total amount of carboxylated polysaccharide to the total amount of sulphated or sulphonated polysaccharide is preferably from 1:2 to 10:1, more preferably from 1:1 to 5:1, most preferably from 3:2 to 0 3:1. WO 2008/119605 PCTYEP2008/052445 - 5 - The preferable, more preferable, and most preferable total amounts of sulphated or sulphonated polysaccharide and the preferable, more preferable, and most preferable ratios of carboxylated polysaccharide to sulphated or sulphonated 5 polysaccharide are believed to be particularly beneficial in delivering the sensory benefits of the present invention, especially at the more typical levels of surfactant and oil inclusion. 10 The toothpaste composition according to the invention may comprise further ingredients. In addition to the aforementioned cellulose derivatives, other materials that modify the rheological properties of the toothpaste may also be employed. Preferred additional ingredients of this type 15 are polyethylene glycols and thickening silicas, such as ® Tixosil 43 , ex Rhddia. Other ingredients of this type are xanthan gum, gum Arabic, synthetic polyacrylates, and synthetic carboxyvinyl polymers such as Carbopol . 20 In addition to the aforementioned triglyceride oil, other oils such as flavouring oils may also be present. Typical flavouring oils include peppermint and spearmint oil. Vitamins sources, in particular sources of vitamin E, such 2 5 as vitamin E acetate are a preferred further ingredient. A source of vitamin E is particular preferred in compositions also comprising sunflower oil, so that sources of both vitamin E and vitamin F are present (vide supra). 30 Antimicrobial agents are further ingredients that may be advantageously employed in compositions of the invention. WO 2008/119605 PCTYEP2008/052445 - 6 - Examples include triclosan, chlorhexidine, copper, zinc and stannous salts (such as zinc citrate, zinc sulphate, zinc glycinate, sodium zinc citrate, stannous pyrophosphate), sanguinarine extract, metronidazole, quaternary ammonium 5 compounds (such as cetylpyridinium chloride), bis-guanides (such as chlorhexidine), digluconate, hexetidine, octenidine, alexidine; and halogenated bisphenolic compounds (such as 2,2'-methylenebis-(4-chloro-6-bromophenol)). 10 Anti-caries agents are further ingredients that may be advantageously employed in compositions of the invention. Examples of such agents include sodium and stannous fluoride, aminefluorides, sodium monofluorophosphate, sodium trimetaphosphate and casein. 15 Polymeric compounds which can enhance the delivery of active ingredients, such as antimicrobial agents, can also be included. Examples of such polymers are copolymers of polyvinylmethylether with maleic anhydride and other similar 20 delivery enhancing polymers, e.g. those described in DE-A-3,942,643 (Colgate). Other ingredients that may be incorporated include: 25 plaque buffers, such as urea, calcium lactate, calcium glycerophosphate and strontium polyacrylates; anti-inflammatory agents, such as ibuprofen, flurbiprofen, aspirin, and indomethacin; 30 WO 2008/119605 PCT/EP2008/052445 - 7 - desensitising agents, such as potassium citrate, potassium chloride, potassium tartrate, potassium bicarbonate, potassium oxalate, potassium nitrate and strontium salts; 5 anti-calculus agents, such as alkali-metal pyrophosphates, hypophosphite-containing polymers, organic phosphonates and phosphocitrates; bio-molecules, such as bacteriocins, antibodies, and 10 enzymes; proteinaceous materials, such as collagen; preservatives; 15 opacifying agents; colouring agents; 20 pH-adjusting agents; sweetening agents, such as saccharin and sorbitol (vide supra) ; 25 bleaching agents, such as peroxy compounds (e.g. potassium peroxydiphosphate); buffers and salts to buffer the pH and ionic strength of the composition; and 30 pharmaceutical^ acceptable carriers, e.g. starch, sucrose, water or water/alcohol systems. Water is a particularly WO 2008/119605 PCT/EP2008/052445 - 8 - preferred pharmaceutically acceptable carrier and is typically present in compositions of the invention at from 5 to 95%, in particular 15 to 75%, and especially at from 35 to 60% by weight of the total composition. Examples In the following examples, comparative examples are indicated by letters and examples according to the invention are indicated by numbers. All amounts of components are indicated as percentages by weight. The toothpaste compositions indicated in Table 1 were prepared by standard methods known in the art. The compositions are identical, with the exception that 0.5% of the SCMC in comparative example A is replaced by carrangeenan in example 1. WO 2008/119605 - 9 - Table 1 Component Trade name Supplier Example A 1 Sorbitol soln. Neosorb 70/70 Cerestar 25.00 25.00 Abrasive silica Sorbosil AC77 Ineos 9.00 9.00 Thickening silica Tixosil 43 Rhodia 7.50 7.50 Poly(ethylene glycol) PEG 32 BASF 5.00 5.00 Surfactant SLS Unger 1.80 1.80 Flavouring oil 1.50 1.50 Zinc citrate Tate&Lyle 0.75 0.75 Sunflower oil Akosun-bha-F1 Akosun 0.50 0.50 SCMC CMC 9M Cekol 1.40 0.90 Carrageenan C'geenan TPC1 Cp Kelko -- 0.50 Phenoxyethanol Lanxess 0.40 0.40 Sodium fluoride Honeywell 0.32 0.32 Anti-microbial Triclosan Ciba 0.30 0.30 Water + minors To 100 To 100 A performance evaluation test of the compositions indicated 5 in Table 1 was carried in order to evaluate user perceptions of the products. 21 trained panellists were employed and asked to evaluate the toothpastes across a range of attributes using a 0 to 10 line scale. The average results concerning the in use perceptions of the toothpastes are 10 indicated in Table 2. WO 2008/119605 PCT/EP2008/052445 - 10 - Table 2 Attribute Score Example A Example 1 Grittiness 0.6 0.5 Foam quantity 6.4 6.4 Foam quality 6.3 6.8 The composition in accordance with the invention was found 5 to give a significantly higher foam quality perception than the comparative example. |
|---|
| Patent Number | 279501 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Indian Patent Application Number | 1752/MUMNP/2009 | ||||||||||||
| PG Journal Number | 04/2017 | ||||||||||||
| Publication Date | 27-Jan-2017 | ||||||||||||
| Grant Date | 24-Jan-2017 | ||||||||||||
| Date of Filing | 18-Sep-2009 | ||||||||||||
| Name of Patentee | HINDUSTAN UNILEVER LIMITED | ||||||||||||
| Applicant Address | UNILEVER HOUSE, B.D. SAWANT MARG, CHAKALA, ANDHERI EAST, MUMBAI-400 099 MAHARASHTRA, INDIA | ||||||||||||
Inventors:
|
|||||||||||||
| PCT International Classification Number | A61Q11/00 | ||||||||||||
| PCT International Application Number | PCT/EP2008/052445 | ||||||||||||
| PCT International Filing date | 2008-02-28 | ||||||||||||
PCT Conventions:
|
|||||||||||||