| Title of Invention | DIARYL AND ARYLHETEROARYL UREA DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO |
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| Abstract | The present invention relates to certain pyrazole derivatives of Formula (I) and pharmaceutical compositions thereof that modulate the activity of the.5-HT2A serotonin receptor. Compounds and pharmaceutical compositions thereof are directed to methods useful in the prophylaxis or treatment of platelet aggregation, coronary artery disease myocardial infarction, transient ischemic attack, angina, stroke, atria! fib- rillation, reducing the risk of blood clot formation, asthma or symptoms thereof, agitation or a symptom, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic-disorder, organic or NOS psychosis, psychotic disorder, psychosis, acute schizophrenia, chronic schizophrenia, NOS schizophrenia and related disorders, and sleep disorders, sleep disorders, diabetic-related disorders and the like. The present invention also relates to the. method of prophylaxis or treatment of 5-HT2A serotonin receptor mediated disorders in combination with a dopamine D2 receptor antagonist such as haloperidol, administered separately or together. |
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02588-kolnp-2005-description complete.pdf
02588-kolnp-2005-international publication.pdf
2588-kolnp-2005-granted-abstract.pdf
2588-kolnp-2005-granted-assignment.pdf
2588-kolnp-2005-granted-claims.pdf
2588-kolnp-2005-granted-correspondence.pdf
2588-kolnp-2005-granted-description (complete).pdf
2588-kolnp-2005-granted-drawings.pdf
2588-kolnp-2005-granted-examination report.pdf
2588-kolnp-2005-granted-form 1.pdf
2588-kolnp-2005-granted-form 18.pdf
2588-kolnp-2005-granted-form 3.pdf
2588-kolnp-2005-granted-form 5.pdf
2588-kolnp-2005-granted-gpa.pdf
2588-kolnp-2005-granted-letter patent.pdf
2588-kolnp-2005-granted-reply to examination report.pdf
2588-kolnp-2005-granted-sequence listing.pdf
2588-kolnp-2005-granted-specification.pdf
| Patent Number | 220494 | ||||||||||||||||||
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| Indian Patent Application Number | 02588/KOLNP/2005 | ||||||||||||||||||
| PG Journal Number | 22/2008 | ||||||||||||||||||
| Publication Date | 30-May-2008 | ||||||||||||||||||
| Grant Date | 28-May-2008 | ||||||||||||||||||
| Date of Filing | 13-Dec-2005 | ||||||||||||||||||
| Name of Patentee | ARENA PHARMACEUTICALS INC | ||||||||||||||||||
| Applicant Address | 6166 NANCY RIDGE DRIVE, SAN DIEGO, CA 92121 | ||||||||||||||||||
Inventors:
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| PCT International Classification Number | C07D 231/16 | ||||||||||||||||||
| PCT International Application Number | PCT/US2004/023488 | ||||||||||||||||||
| PCT International Filing date | 2004-07-21 | ||||||||||||||||||
PCT Conventions:
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