| Title of Invention | METHOD OF PRODUCING ETHYL (3R, 5S,6E)-7-[2-CYCLOPROPYL-4-(4-FLUOROPHENYL)QUINOLINE-3-YL]-3,5-DIHYDROXY-6-HEPTENOATE |
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| Abstract | The present invention relates to a method for producing ethyl (3R, 5S, 6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)qunoline-3-yl]-3, 5-dihydroxy-6-heptanoate from a solution containing a mixture of optical isomers of ethyl 6E-7-[2-cyclopropyl-4-(4-fluorophenyl)qunoline-3-yl]-3,5-dihydroxy-6-heptanoate by means of the liquid chromatography using a packing material having a carrier and, carried thereon, a polysaccharide derivative, characterized in that a part or all of the hydrogen atoms of the hydroxyl groups and amino groups of the polysaccharide derivative are substituted with one or more substituents, such as a carbamoyl group wherein one hydrogen atom is substituted with an aromatic group having a specific alkyl group. The method allows the production of the above (3R, 5S, 6E) isomer with enhanced productivity compared to a conventional method. |
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3125-chenp-2005 abstract-duplicate.pdf
3125-chenp-2005 claims-duplicate.pdf
3125-chenp-2005 correspondence-others.pdf
3125-chenp-2005 correspondence-po.pdf
3125-chenp-2005 descripition(completed)-duplicate.pdf
3125-chenp-2005 descripition(completed).pdf
3125-chenp-2005 drawings-duplicate.pdf
| Patent Number | 229447 | |||||||||
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| Indian Patent Application Number | 3125/CHENP/2005 | |||||||||
| PG Journal Number | 12/2009 | |||||||||
| Publication Date | 20-Mar-2009 | |||||||||
| Grant Date | 17-Feb-2009 | |||||||||
| Date of Filing | 23-Nov-2005 | |||||||||
| Name of Patentee | DAICEL CHEMICAL INDUSTRIES, LTD. | |||||||||
| Applicant Address | MAINICHI INTECIO., 3-4-5, UMEDA, KITA-KU, OSAKA-SHI, OSAKA 530-001, | |||||||||
Inventors:
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| PCT International Classification Number | C07D 215/12 | |||||||||
| PCT International Application Number | PCT/JP04/05894 | |||||||||
| PCT International Filing date | 2004-04-23 | |||||||||
PCT Conventions:
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