Title of Invention | ANTIBODIES WITH VARIANT Fc REGIONS |
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Abstract | The present invention relates to an antibody comprising a variant Fc region, wherein the variant Fc region comprises at least one amino acid modification including a modification at position 396 relative to a wild-type Fc region, such that the antibody specifically binds FcyRIIIA with a greater affinity than a comparable antib?dy comprising the wild-type Fc region binds FcyRIIIA. |
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1849-CHENP-2005 CORRESPONDENCE OTHERS.pdf
1849-CHENP-2005 CORRESPONDENCE PO.pdf
1849-CHENP-2005 DESCRIPTION (COMPLETE) GRANTED.pdf
1849-CHENP-2005 POWER OF ATTORNEY.pdf
Patent Number | 230243 | ||||||||||||||||
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Indian Patent Application Number | 1849/CHENP/2005 | ||||||||||||||||
PG Journal Number | 13/2009 | ||||||||||||||||
Publication Date | 27-Mar-2009 | ||||||||||||||||
Grant Date | 25-Feb-2009 | ||||||||||||||||
Date of Filing | 08-Aug-2005 | ||||||||||||||||
Name of Patentee | MACROGENICS, INC. | ||||||||||||||||
Applicant Address | 1500 East Gude Drive, Rockville, MD 20850-5307, | ||||||||||||||||
Inventors:
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PCT International Classification Number | C12N | ||||||||||||||||
PCT International Application Number | PCT/US2004/000643 | ||||||||||||||||
PCT International Filing date | 2004-01-09 | ||||||||||||||||
PCT Conventions:
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