Title of Invention

ANTIBODIES WITH VARIANT Fc REGIONS

Abstract The present invention relates to an antibody comprising a variant Fc region, wherein the variant Fc region comprises at least one amino acid modification including a modification at position 396 relative to a wild-type Fc region, such that the antibody specifically binds FcyRIIIA with a greater affinity than a comparable antib?dy comprising the wild-type Fc region binds FcyRIIIA.
Full Text

Documents:

1849-CHENP-2005 ABSTRACT.pdf

1849-CHENP-2005 CLAIMS.pdf

1849-CHENP-2005 CORRESPONDENCE OTHERS.pdf

1849-CHENP-2005 CORRESPONDENCE PO.pdf

1849-CHENP-2005 DESCRIPTION (COMPLETE) GRANTED.pdf

1849-CHENP-2005 DRAWINGS.pdf

1849-CHENP-2005 FORM-1.pdf

1849-CHENP-2005 FORM-18.pdf

1849-CHENP-2005 FORM-3.pdf

1849-CHENP-2005 FORM-5.pdf

1849-CHENP-2005 PCT.pdf

1849-CHENP-2005 PETITION.pdf

1849-CHENP-2005 POWER OF ATTORNEY.pdf


Patent Number 230243
Indian Patent Application Number 1849/CHENP/2005
PG Journal Number 13/2009
Publication Date 27-Mar-2009
Grant Date 25-Feb-2009
Date of Filing 08-Aug-2005
Name of Patentee MACROGENICS, INC.
Applicant Address 1500 East Gude Drive, Rockville, MD 20850-5307,
Inventors:
# Inventor's Name Inventor's Address
1 STAVENHAGEN, Jeffrey 19417 Treadway Road, Brookville, MD 20833,
2 VIJH, Sujata 912-100 Orchard Ridge Drive, Gaithersburg, MD 20878,
PCT International Classification Number C12N
PCT International Application Number PCT/US2004/000643
PCT International Filing date 2004-01-09
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 60/514,549 2003-10-23 U.S.A.
2 60/439,498 2003-01-09 U.S.A.
3 60/456,041 2003-03-19 U.S.A.