Title of Invention

A METHOD FOR INDUSTRIAL PRODUCTION OF BIOCATALYSTS IN THE FORM OF ENZYMES OR MICROORGANISMS IMMOBILIZED IN POLYVINYL ALCOHOL GEL, THEIR USE DEVICES FOR THEIR PRODUCTION

Abstract A method for the industrial production of the biocatalysts with biologically active material in the form of immobilized enzymes or microorganisms which are immobilized into the polyvinyl alcohol gel, and their use based on the fact, that the active biological material, formed by the mixture of free native or pretrated (aggregated) enzyme catalyst, or production microorganism, or part of them, and the polyvinyl alcohol gel, is used for their industrial production, the mixture is gelated and shaped in a stream of drying air at the temperature of 800C to 150C, considering the extent of the biologically active material, at the biocatalyst geometrical ratio of the surface to the volume kept larger than 7 mm"1, and consequently thus prepared biocatalysts can be cultivated or stored and then use in biotechnological processes in the conditions, which ensure given biotechnological process higher productivity, higher production and enzymatic stability, long-term and repeated usage or definable process control with consequence easy separation of the biocatalyst. The industrial production device, providing optimization of the biological carrier volume and surface in dependence on biologically active material extent, consisting of a casting mechanism (17) mounted in front of a drying channel (2), through which a continuous conveyor belt (1) runs, is equipped with at least one casting head (17) with two rows of casting needle injectors connected to a pressure tempered tank (15) and a compressor (16), the conveyor belt (1) and a drying system - the source (4) of a drying air, which is blown by means of ventilator into an air distribution system (6) with incorporated heating elements (5), which runs into the upper drying channel (2), and further the lower final drying channel (3) and a reswelling tank (7), between which a wiping and collecting device (9) is mounted, designed on the basis of mechanical wiping and high-pressure rinse, which is connected to a pipeline with integrated high-pressure pump (10) and low-pressure pump (11) running into a collecting reservoir (8) with cooling and further a rinse box (13) for continuous conveyor belt (1) final cleaning by jets connected to a low- pressure pump (14), which is connected to a rinse tank (12) by pipeline.
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Documents:

http://ipindiaonline.gov.in/patentsearch/GrantedSearch/viewdoc.aspx?id=qosuMuSllUBm9UsXnDVEdQ==&loc=+mN2fYxnTC4l0fUd8W4CAA==


Patent Number 269095
Indian Patent Application Number 8320/DELNP/2008
PG Journal Number 40/2015
Publication Date 02-Oct-2015
Grant Date 30-Sep-2015
Date of Filing 01-Oct-2008
Name of Patentee LENTIKAT'S A.S
Applicant Address EVROPSKA 423/178, 160 00 PRAHA (CZ)
Inventors:
# Inventor's Name Inventor's Address
1 STOUKAL, RADEK CVIKOVSKA 2871, 470 01 CESKA LIPA (CZ)
2 ROSENBERG, MICHAL ZAHREBSKA 8, 811 05 BRATISLAVA (SK)
3 REBROS, MARTIN M.R. STEFANIKA 2560, 022 01 CADCA (SK)
PCT International Classification Number A61K 9/00
PCT International Application Number PCT/CZ2007/000015
PCT International Filing date 2007-03-06
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 PUV 2006-17510 2006-03-13 Czech Republic